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Hongsheng Dai
Basic Medical Sciences
Southern Medical University
Guangdong
Language: English, Chinese
Vaccine
Virus
Immunology
Therapy
Nk Cells
Immune Response
Treatment
Innovation
Research
Health
Areas of Focus
- Novel Viral Vaccines
- NK Cell Function
- Novel Immunotherapy
Work Experience
- From December 2019 - Southern Medical University, Professor, Doctoral Supervisor
- July 2018 - October 2019 - City of Hope National Medical Center, Assistant Research Professor
- November 2017 - June 2018 - The Ohio State University, Research Scientist
- June 2013 - October 2017 - The Ohio State University, Postdoctoral Researcher
Academic Background & Achievements
- 2008-2012 Ph.D. in Molecular Virology: Purdue University
- 2000-2007 Bachelor's and Master's in Clinical Medicine: Nankai University
Publications
- The Fc Domain of Immunoglobulin Is Sufficient to Bridge NK Cells with Virally Infected Cells, Dai HS*, Griffin N, Bolyard C, Mao C, Zhang J, Cripe T, Suenaga T, Arase H, Nakano I, Chiocca E, Kaur B, Yu J, Caligiuri MA*, 2017
- Molecular basis for the recognition of HSV1 infection by human NK cells, Dai HS* and Caligiuri MA*, 2018
- Directed evolution of a virus exclusively utilizing human epidermal growth factor receptor as the entry receptor, Dai HS*, Liu Z, Jiang W, Kuhn RJ*, 2013
- An oncolytic herpesvirus expressing E-cadherin improves survival in mouse models of glioblastoma, Xu B, Ma R, Russell L, Yoo JY, Han J, Cui H, Yi P, Zhang J, Nakashima H, Dai HS, Chiocca EA, Kaur B, Caligiuri MA, Yu J, 2019
- Bortezomib Treatment Sensitizes Oncolytic HSV-1-Treated Tumors to NK Cell Immunotherapy, Yoo JY, Jaime-Ramirez AC, Bolyard C, Dai HS, Nallanagulagari T, Wojton J, Hurwitz BS, Relation T, Lee TJ, Lotze MT, Yu JG, Zhang J, Croce CM, Yu J, Caligiuri MA, Old M, Kaur B, 2016
- Oncolytic HSV infected glioma cells activate NOTCH in adjacent tumor cells sensitizing tumors to gamma secretase inhibition, Otani Y, Yoo JY, Chao S, Liu J, Jaime-Ramirez AC, Lee TJ, Hurwitz B, Yan Y, Dai HS, Glorioso JC, Caligiuri MA, Yu J, Kaur B, 2020
Awards
- Immunology 2020, Travel Grant, AAI ($1500)
