Professor | Rui-Yuan Pan | Asia Growth Partners

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Name	Rui-Yuan Pan
Contact Information	panruiyuan168@sina.com
Language ability	Chinese, English
Province	Guangdong

Upload Avatar (500 x 500)

Name

Rui-Yuan Pan

Contact Information

panruiyuan168@sina.com

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	PhD: Institute of Biophysics, Chinese Academy of Sciences Postdoctoral: Academy of Military Medical Sciences 2022: Selected for the China Association for Science and Technology Youth Talent Support Project 2023: High-level talent introduction at Southern Medical University
Work Experience	2023 - Present: Southern Medical University - High-level talent introduction 2020 - 2022: Academy of Military Medical Sciences - Postdoctoral Researcher
Awards	2022: Selected for the China Association for Science and Technology Youth Talent Support Project

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

PhD: Institute of Biophysics, Chinese Academy of Sciences
Postdoctoral: Academy of Military Medical Sciences
2022: Selected for the China Association for Science and Technology Youth Talent Support Project
2023: High-level talent introduction at Southern Medical University

Work Experience

2023 - Present: Southern Medical University - High-level talent introduction
2020 - 2022: Academy of Military Medical Sciences - Postdoctoral Researcher

Awards

2022: Selected for the China Association for Science and Technology Youth Talent Support Project

Areas of Focus	Pathogenesis and intervention strategies of Alzheimer's disease Molecular mechanisms of glial cell metabolism and neuroinflammation regulation Role and mechanisms of the gut-brain axis in neurological diseases
Publications	Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease, Rui-Yuan Pan, Lin He, Jing Zhang, Xinhua Liu, Yajin Liao, Ju Gao, Yang Liao, Yuhan Yan, Qianqian Li, Xuehong Zhou, Jinbo Cheng, Qu Xing, Fangxia Guan, Jie Zhang, Luyang Sun, Zengqiang Yuan, 2022 Intermittent fasting protects against Alzheimer’s disease in mice by altering metabolism through remodeling of the gut microbiota, Rui-Yuan Pan, Jing Zhang, Jinlei Wang, Yingyi Wang, Zhihui Li, Yang Liao, Yajin Liao, Chenggang Zhang, Zhiqiang Liu, Lijuan Song, Jiezhong Yu, Zengqiang Yuan, 2022 Nao Tan Qing ameliorates Alzheimer's disease-like pathology by regulating glycolipid metabolism and neuroinflammation: A network pharmacology analysis and biological validation, Qianqian Li, Caixia Jia, Hongxing Wu, Yajin Liao, Ke Yang, Shuoshuo Li, Jing Zhang, Jinlei Wang, Guo Li, Fangxia Guan, Elaine Leung, Zengqiang Yuan, Qian Hua, Rui-Yuan Pan, 2022 Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance, Lige Leng, Ziqi Yuan, Rui-Yuan Pan, Xiao Su, Han Wang, Jin Xue, Kai Zhuang, Ju Gao, Zhenlei Chen, Hui Lin, Wenting Xie, Huifang Li, Zhenyi Chen, Keke Ren, Xiao Zhang, Wenting Wang, Zi-Bing Jin, Shengxi Wu, Xinglong Wang, Zengqiang Yuan, Huaxi Xu, Hei-Man Chow, Jie Zhang, 2022 1,2,4-Trimethoxybenzene selectively inhibits NLRP3 inflammasome activation and attenuates experimental autoimmune encephalomyelitis, Rui-Yuan Pan, Xiang-xi Kong, Yong Cheng, Lu Du, Zhen-chao Wang, Chao Yuan, Jin-bo Cheng, Zeng-qiang Yuan, Hai-yan Zhang, Ya-jin Liao, 2021 Astrocytes in depression and Alzheimer’s disease, Yang Liao, Qu Xing, Qianqian Li, Jing Zhang, Rui-Yuan Pan, Zengqiang Yuan, 2021 Sodium rutin extends lifespan and health span in mice including positive impacts on liver health., Shuoshuo Li, Jun Li, Rui-Yuan Pan, Jinbo Cheng, Qinghua Cui, Jianxin Chen, Zengqiang Yuan, 2021 Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology., Jinbo Cheng, Yuan Dong, Jun Ma, Rui-Yuan Pan, Yajin Liao, Xiangxi Kong, Xiaoheng Li, Shuoshuo Li, Pingfang Chen, Liang Wang, Ye Yu, Zengqiang Yuan, 2021 Sodium rutin ameliorates Alzheimer’s disease–like pathology by enhancing microglial amyloid-β clearance, Rui-Yuan Pan, Jun Ma, Xiang-Xi Kong, Xiao-Feng Wang, Shuo-Shuo Li, Xiao-Long Qi, Yu-Han Yan, Jinbo Cheng, Qingsong Liu, Wanzhu Jin, Chang-Heng Tan, Zengqiang Yuan, 2019 Calhm2 governs astrocytic ATP releasing in the development of depression-like behaviors, Jun Ma, Xiaolong Qi, Chaojuan Yang, Rui-Yuan Pan, Shukun Wang, Junbing Wu, Li Huang, Hong Chen, Jinbo Cheng, Rong Wu, Yajin Liao, Lanqun Mao, Fengchao Wang, Zhiying Wu, Jianxiong An, Yun Wang, Xia Zhang, Chen Zhang, Zengqiang Yuan, 2018

Areas of Focus

Pathogenesis and intervention strategies of Alzheimer's disease
Molecular mechanisms of glial cell metabolism and neuroinflammation regulation
Role and mechanisms of the gut-brain axis in neurological diseases

Publications

Positive feedback regulation of microglial glucose metabolism by histone H4 lysine 12 lactylation in Alzheimer’s disease, Rui-Yuan Pan, Lin He, Jing Zhang, Xinhua Liu, Yajin Liao, Ju Gao, Yang Liao, Yuhan Yan, Qianqian Li, Xuehong Zhou, Jinbo Cheng, Qu Xing, Fangxia Guan, Jie Zhang, Luyang Sun, Zengqiang Yuan, 2022
Intermittent fasting protects against Alzheimer’s disease in mice by altering metabolism through remodeling of the gut microbiota, Rui-Yuan Pan, Jing Zhang, Jinlei Wang, Yingyi Wang, Zhihui Li, Yang Liao, Yajin Liao, Chenggang Zhang, Zhiqiang Liu, Lijuan Song, Jiezhong Yu, Zengqiang Yuan, 2022
Nao Tan Qing ameliorates Alzheimer's disease-like pathology by regulating glycolipid metabolism and neuroinflammation: A network pharmacology analysis and biological validation, Qianqian Li, Caixia Jia, Hongxing Wu, Yajin Liao, Ke Yang, Shuoshuo Li, Jing Zhang, Jinlei Wang, Guo Li, Fangxia Guan, Elaine Leung, Zengqiang Yuan, Qian Hua, Rui-Yuan Pan, 2022
Microglial hexokinase 2 deficiency increases ATP generation through lipid metabolism leading to β-amyloid clearance, Lige Leng, Ziqi Yuan, Rui-Yuan Pan, Xiao Su, Han Wang, Jin Xue, Kai Zhuang, Ju Gao, Zhenlei Chen, Hui Lin, Wenting Xie, Huifang Li, Zhenyi Chen, Keke Ren, Xiao Zhang, Wenting Wang, Zi-Bing Jin, Shengxi Wu, Xinglong Wang, Zengqiang Yuan, Huaxi Xu, Hei-Man Chow, Jie Zhang, 2022
1,2,4-Trimethoxybenzene selectively inhibits NLRP3 inflammasome activation and attenuates experimental autoimmune encephalomyelitis, Rui-Yuan Pan, Xiang-xi Kong, Yong Cheng, Lu Du, Zhen-chao Wang, Chao Yuan, Jin-bo Cheng, Zeng-qiang Yuan, Hai-yan Zhang, Ya-jin Liao, 2021
Astrocytes in depression and Alzheimer’s disease, Yang Liao, Qu Xing, Qianqian Li, Jing Zhang, Rui-Yuan Pan, Zengqiang Yuan, 2021
Sodium rutin extends lifespan and health span in mice including positive impacts on liver health., Shuoshuo Li, Jun Li, Rui-Yuan Pan, Jinbo Cheng, Qinghua Cui, Jianxin Chen, Zengqiang Yuan, 2021
Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer's disease pathology., Jinbo Cheng, Yuan Dong, Jun Ma, Rui-Yuan Pan, Yajin Liao, Xiangxi Kong, Xiaoheng Li, Shuoshuo Li, Pingfang Chen, Liang Wang, Ye Yu, Zengqiang Yuan, 2021
Sodium rutin ameliorates Alzheimer’s disease–like pathology by enhancing microglial amyloid-β clearance, Rui-Yuan Pan, Jun Ma, Xiang-Xi Kong, Xiao-Feng Wang, Shuo-Shuo Li, Xiao-Long Qi, Yu-Han Yan, Jinbo Cheng, Qingsong Liu, Wanzhu Jin, Chang-Heng Tan, Zengqiang Yuan, 2019
Calhm2 governs astrocytic ATP releasing in the development of depression-like behaviors, Jun Ma, Xiaolong Qi, Chaojuan Yang, Rui-Yuan Pan, Shukun Wang, Junbing Wu, Li Huang, Hong Chen, Jinbo Cheng, Rong Wu, Yajin Liao, Lanqun Mao, Fengchao Wang, Zhiying Wu, Jianxiong An, Yun Wang, Xia Zhang, Chen Zhang, Zengqiang Yuan, 2018

Alzheimer'S Disease Glial Cells Neuroinflammation Energy Metabolism Epigenetics Gut-Brain Axis Pathogenesis Intervention Strategies Molecular Mechanisms Neurological Diseases

Ma Rong Fang - Zhejiang University

Xiaomin Wang - Capital Medical University

Zhilin Li - Guangzhou Medical University

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