Professor | Zhang Sheng | Asia Growth Partners

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Name

Zhang Sheng

Contact Information

zhang.sheng1@outlook.com

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2009-2014: PhD at Guangzhou University of Chinese Medicine Published 3 SCI papers as first author in the field of Parkinson's disease
Work Experience	2015-2022: Postdoctoral and Researcher at University of California, Davis and Mayo Clinic Led postdoctoral project at UC Davis Children's Hospital
Awards	2016: Guangdong Science and Technology Progress Award, Second Prize 2017: Chinese Association of Traditional Chinese Medicine Science and Technology Award, Third Prize 2016: Patent for a drug composition for Parkinson's disease

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

Work Experience

2015-2022: Postdoctoral and Researcher at University of California, Davis and Mayo Clinic
Led postdoctoral project at UC Davis Children's Hospital

Awards

2016: Guangdong Science and Technology Progress Award, Second Prize
2017: Chinese Association of Traditional Chinese Medicine Science and Technology Award, Third Prize
2016: Patent for a drug composition for Parkinson's disease

Areas of Focus	Mechanisms of glial cells and myelin in neurodevelopment and immune degenerative diseases
Publications	Glial cell specific regulation of CNS angiogenesis by Hifα-activated different signaling pathways, Zhang S, Kim BK, et al., and Guo FZ., 2020 The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling, Zhang S, Wang Y, et al., and Guo FZ., 2021 HIFα regulates developmental myelination independent of autocrine Wnt signaling, Zhang S, Wang Y, et al., and Guo FZ., 2021 Sox2 is essential for oligodendroglial proliferation and differentiation during postnatal brain myelination and CNS remyelination, Zhang S, Zhu XQ, et al., and Guo FZ., 2018 The Stem Cell Factor Sox2 Is a Positive Timer of Oligodendrocyte Development in the Postnatal Murine Spinal Cord, Zhang S, et al., and Guo FZ., 2018 Sox2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice, Wang Y, Zhang S, Zhaohui Lan* et al., and Guo FZ., 2022 PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination, Wang Y, Zhang YH, Zhang S, et al., and Guo FZ., 2021

Areas of Focus

Mechanisms of glial cells and myelin in neurodevelopment and immune degenerative diseases

Publications

Glial cell specific regulation of CNS angiogenesis by Hifα-activated different signaling pathways, Zhang S*, Kim BK*, et al., and Guo FZ., 2020
The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling, Zhang S*, Wang Y*, et al., and Guo FZ., 2021
HIFα regulates developmental myelination independent of autocrine Wnt signaling, Zhang S, Wang Y, et al., and Guo FZ., 2021
Sox2 is essential for oligodendroglial proliferation and differentiation during postnatal brain myelination and CNS remyelination, Zhang S*, Zhu XQ*, et al., and Guo FZ., 2018
The Stem Cell Factor Sox2 Is a Positive Timer of Oligodendrocyte Development in the Postnatal Murine Spinal Cord, Zhang S, et al., and Guo FZ., 2018
Sox2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice, Wang Y*, Zhang S*, Zhaohui Lan* et al., and Guo FZ., 2022
PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination, Wang Y, Zhang YH, Zhang S, et al., and Guo FZ., 2021

Glia Demyelination Remyelination Neurodevelopment Neurodegenerative Disease Glial Cells Myelin Immune System Cns Neuroscience

Ying Shen - Zhejiang University

Chunling Fan - Central South University

Lu Xi Wang - Zhejiang University

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