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Xuefei Gao
Basic Medical Sciences
Southern Medical University
Guangdong
Language: English, Chinese
Human Pluripotent Stem Cell
Pluripotent Maintenance
Trophoblasts
Lineage Specification
Fate Commitment
Stem Cell
Differentiation
Regulation
Biology
Research
Areas of Focus
- Maintenance of pluripotency in human pluripotent stem cells and regulation of trophoblast lineage differentiation
Work Experience
- 2011.09-2018.07 - Sanger Institute, Cambridge - Senior Staff Scientist
- 2018.07-2019.08 - University of Hong Kong - Research Assistant Professor
- 2019.09-present - Southern Medical University - Professor
Academic Background & Achievements
- 2006.08-2011.08 PhD in Biochemistry and Molecular Biology: Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
- Achievement: Senior Staff Scientist at Sanger Institute, Cambridge
Publications
- SP6 controls human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements., Chen Y, Ye X, Zhong Y, Kang X, Tang Y, Zhu H, Pang C, Ning S, Liang S, Zhang F, Li C, Li J, Gu C, Cheng Y, Kuang Z, Qiu J, Jin J, Luo H, Fu M, Hui HX, Li L, Ruan D, Liu P, Chen X, Sun L, Ai S, Gao X., 2024
- An optimized culture system for efficient derivation of porcine expanded potential stem cells from preimplantation embryos and by reprogramming somatic cells., Ruan D, Xuan Y, Tam TTK, Li Z, Wang X, Xu S, Herrmann D, Niemann H, Lai L, Gao X, Nowak-Imialek M, Liu P., 2024
- Establishment of bovine expanded potential stem cells., Zhao L, Gao X, Zheng Y, Wang Z, Zhao G, Ren J, Zhang J, Wu J, Wu B, Chen Y, Sun W, Li Y, Su J, Ding Y, Gao Y, Liu M, Bai X, Sun L, Cao G, Tang F, Bao S, Liu P, Li X., 2021
- Establishment of Porcine and Human Expanded Potential Stem Cells., Gao X, Nowak-Imialek M, Chen X, Chen D, Herrmann D, Ruan D, Andy Chen CH Andy, Eckersley-Maslin M, Shakil A, Lee YL, Kobayashi T, Ryan D, Tam PL P, Ahmed A, Wu D, Nie T, Pei D, Surani A, Shang Z, Lai L, Yeung SBW, Teichmann S, Niemann H, Liu P., 2019
- Comparison of TALE Designer Transcription Factors and the CRISPR/dCas9 in Regulation of Gene Expression by Targeting Enhancers., Gao X, Jason CH Tsang, Fortis Gaba, Donghai Wu, Pentao Liu., 2014
- Reprogramming to Pluripotency Using Designer TALE Transcription Factors Targeting Enhancers., Gao X, Yang J, Tsang JC, Ooi Jolene, Wu D, Liu P., 2013
- Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase., Gao X, Li K, Hui X, Kong X, Sweeney G, Wang Y, Xu A, Teng M, Liu P, Wu D., 2011
- Enhanced susceptibility of Cpt1c knockout mice to glucose intolerance induced by a high-fat diet involves elevated hepatic gluconeogenesis and decreased skeletal muscle glucose uptake., Gao X, Chen W, Kong XP, Xu AM, Wang ZG, Sweeney G, Wu D., 2009
