Professor | Peng Gu | Asia Growth Partners

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Name	Peng Gu
Contact Information	kupper@smu.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Peng Gu

Contact Information

kupper@smu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2016.09-2021.06 Doctorate: Southern Medical University 2011.09-2016.06 Bachelor's: South China Agricultural University
Work Experience	2021.09-2024.01 - Southern Medical University Shenzhen Hospital - Postdoctoral Researcher 2024.02-present - Southern Medical University, School of Basic Medical Sciences - Associate Professor

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2016.09-2021.06 Doctorate: Southern Medical University
2011.09-2016.06 Bachelor's: South China Agricultural University

Work Experience

2021.09-2024.01 - Southern Medical University Shenzhen Hospital - Postdoctoral Researcher
2024.02-present - Southern Medical University, School of Basic Medical Sciences - Associate Professor

Areas of Focus	Development of genetically engineered bacteria Prevention and treatment of gut microbiota and multi-organ injury
Publications	An engineered Escherichia coli Nissle strain prevents lethal liver injury in a mouse model of tyrosinemia type 1., Gu P, Xie L, Chen T, Yang Q, Zhang X, Liu R, Guo J, Wei, R, Li D, J, Chen Y, Gong W, Chen P., 2024 A metabolite from commensal Candida albicans enhances the bactericidal activity of macrophages and protects against sepsis., Gu P, Liu R, Yang Q, Xie L, Wei R, Li J, Mei F, Chen T, Zeng Z, He Y, Zhou H, Peng H, Nandakumar K, Chu H, Jiang Y, Gong W, Chen Y, Schnabl B, Chen P., 2023 Genetically blocking HPD via CRISPR-Cas9 protects against lethal liver injury in a pig model of tyrosinemia type I., Gu P, Yang Q, Chen B, Bie YN, Liu W, Tian Y, Luo H, Xu T, Liang C, Ye X, Liu Y, Tang X, Gu W., 2021 Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection., Chen B, Gu P, Jia J, Liu W, Liu Y, Liu W, Xu T, Lin X, Lin T, Liu Y, Chen H, Xu M, Yuan J, Zhang J, Zhang Y, Xiao D, Gu W., 2019 TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway., Bie Y, Gu P, Chen Y, Zhou X, Tian Y, Yang Q, Li H, Lin X, Guan Y, Lin T, Lu X, Shen H, Fang T, Liu Y, Xiao D, Gu W., 2019 Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis., Xie S, Li J, Lyu F, Xiong Q, Gu P, Chen Y, Chen M, Bao J, Zhang X, Wei R, Deng Y, Wang H, Zeng Z, Chen Z, Deng Y, Lian Z, Zhao J, Gong W, Chen Y, Liu KX, Duan Y, Jiang Y, Zhou HW, Chen P., 2023 Oral magnesium prevents acetaminophen-induced acute liver injury by modulating microbial metabolism., Li D, Chen Y, Wan M, Mei F, Wang F, Gu P, Zhang X, Wei R, Zeng Y, Zheng H, Chen B, Xiong Q, Xue T, Guan T, Guo J, Tian Y, Zeng L, Liu Z, Yuan H, Yang L, Liu H, Dai L, Yu Y, Qiu Y, Wu P, Win S, Than T, Wei R, Schnabl B, Kaplowitz N, Jiang Y, Ma Q, Chen P., 2024

Areas of Focus

Development of genetically engineered bacteria
Prevention and treatment of gut microbiota and multi-organ injury

Publications

An engineered Escherichia coli Nissle strain prevents lethal liver injury in a mouse model of tyrosinemia type 1., Gu P, Xie L, Chen T, Yang Q, Zhang X, Liu R, Guo J, Wei, R, Li D, J, Chen Y, Gong W, Chen P., 2024
A metabolite from commensal Candida albicans enhances the bactericidal activity of macrophages and protects against sepsis., Gu P, Liu R, Yang Q, Xie L, Wei R, Li J, Mei F, Chen T, Zeng Z, He Y, Zhou H, Peng H, Nandakumar K, Chu H, Jiang Y, Gong W, Chen Y, Schnabl B, Chen P., 2023
Genetically blocking HPD via CRISPR-Cas9 protects against lethal liver injury in a pig model of tyrosinemia type I., Gu P, Yang Q, Chen B, Bie YN, Liu W, Tian Y, Luo H, Xu T, Liang C, Ye X, Liu Y, Tang X, Gu W., 2021
Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection., Chen B, Gu P, Jia J, Liu W, Liu Y, Liu W, Xu T, Lin X, Lin T, Liu Y, Chen H, Xu M, Yuan J, Zhang J, Zhang Y, Xiao D, Gu W., 2019
TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway., Bie Y, Gu P, Chen Y, Zhou X, Tian Y, Yang Q, Li H, Lin X, Guan Y, Lin T, Lu X, Shen H, Fang T, Liu Y, Xiao D, Gu W., 2019
Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis., Xie S, Li J, Lyu F, Xiong Q, Gu P, Chen Y, Chen M, Bao J, Zhang X, Wei R, Deng Y, Wang H, Zeng Z, Chen Z, Deng Y, Lian Z, Zhao J, Gong W, Chen Y, Liu KX, Duan Y, Jiang Y, Zhou HW, Chen P., 2023
Oral magnesium prevents acetaminophen-induced acute liver injury by modulating microbial metabolism., Li D, Chen Y, Wan M, Mei F, Wang F, Gu P, Zhang X, Wei R, Zeng Y, Zheng H, Chen B, Xiong Q, Xue T, Guan T, Guo J, Tian Y, Zeng L, Liu Z, Yuan H, Yang L, Liu H, Dai L, Yu Y, Qiu Y, Wu P, Win S, Than T, Wei R, Schnabl B, Kaplowitz N, Jiang Y, Ma Q, Chen P., 2024

Gene Editing Gut Microbiota Infection Immunology Rare Disease Bacteria Organ Injury Prevention Treatment Research

Kong Wei - Peking University

Li-Hua Qin - Peking University

Xiaoyan Qiu - Peking University

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