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Peng Gu
Basic Medical Sciences
Southern Medical University
Guangdong
Language: Chinese, English
Gene Editing
Gut Microbiota
Infection
Immunology
Rare Disease
Bacteria
Organ Injury
Prevention
Treatment
Research
Areas of Focus
- Development of genetically engineered bacteria
- Prevention and treatment of gut microbiota and multi-organ injury
Work Experience
- 2021.09-2024.01 - Southern Medical University Shenzhen Hospital - Postdoctoral Researcher
- 2024.02-present - Southern Medical University, School of Basic Medical Sciences - Associate Professor
Academic Background & Achievements
- 2016.09-2021.06 Doctorate: Southern Medical University
- 2011.09-2016.06 Bachelor's: South China Agricultural University
Publications
- An engineered Escherichia coli Nissle strain prevents lethal liver injury in a mouse model of tyrosinemia type 1., Gu P, Xie L, Chen T, Yang Q, Zhang X, Liu R, Guo J, Wei, R, Li D, J, Chen Y, Gong W, Chen P., 2024
- A metabolite from commensal Candida albicans enhances the bactericidal activity of macrophages and protects against sepsis., Gu P, Liu R, Yang Q, Xie L, Wei R, Li J, Mei F, Chen T, Zeng Z, He Y, Zhou H, Peng H, Nandakumar K, Chu H, Jiang Y, Gong W, Chen Y, Schnabl B, Chen P., 2023
- Genetically blocking HPD via CRISPR-Cas9 protects against lethal liver injury in a pig model of tyrosinemia type I., Gu P, Yang Q, Chen B, Bie YN, Liu W, Tian Y, Luo H, Xu T, Liang C, Ye X, Liu Y, Tang X, Gu W., 2021
- Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection., Chen B, Gu P, Jia J, Liu W, Liu Y, Liu W, Xu T, Lin X, Lin T, Liu Y, Chen H, Xu M, Yuan J, Zhang J, Zhang Y, Xiao D, Gu W., 2019
- TZAP plays an inhibitory role in the self-renewal of porcine mesenchymal stromal cells and is implicated the regulation of premature senescence via the p53 pathway., Bie Y, Gu P, Chen Y, Zhou X, Tian Y, Yang Q, Li H, Lin X, Guan Y, Lin T, Lu X, Shen H, Fang T, Liu Y, Xiao D, Gu W., 2019
- Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis., Xie S, Li J, Lyu F, Xiong Q, Gu P, Chen Y, Chen M, Bao J, Zhang X, Wei R, Deng Y, Wang H, Zeng Z, Chen Z, Deng Y, Lian Z, Zhao J, Gong W, Chen Y, Liu KX, Duan Y, Jiang Y, Zhou HW, Chen P., 2023
- Oral magnesium prevents acetaminophen-induced acute liver injury by modulating microbial metabolism., Li D, Chen Y, Wan M, Mei F, Wang F, Gu P, Zhang X, Wei R, Zeng Y, Zheng H, Chen B, Xiong Q, Xue T, Guan T, Guo J, Tian Y, Zeng L, Liu Z, Yuan H, Yang L, Liu H, Dai L, Yu Y, Qiu Y, Wu P, Win S, Than T, Wei R, Schnabl B, Kaplowitz N, Jiang Y, Ma Q, Chen P., 2024
