Professor | Yuan Kai | Asia Growth Partners

Name	Yuan Kai
Contact Information	yuankai@csu.edu.cn
Language ability	Chinese, English
Province	Hunan

Name

Yuan Kai

Contact Information

yuankai@csu.edu.cn

Language ability

Chinese, English

Province

Hunan

University/Lab Affiliation and Title	Central South University
Faculty	Life Sciences
Academic Background & Achievements	2000.9-2004.7 Bachelor of Science, School of Life Sciences, University of Science and Technology of China 2004.9-2009.12 Doctor of Science, Department of Cell and Molecular Biology, University of Science and Technology of China
Work Experience	2010.4-2016.3 Postdoctoral Researcher, Department of Biochemistry, University of California, San Francisco 2016.4-2017.1 Specialist, Department of Biochemistry, University of California, San Francisco 2017.2-present Researcher, Institute of Precision Molecular Medicine, Xiangya Hospital, Central South University 2019.11-present Director, Clinical Biosample Center, Xiangya Hospital, Central South University
Awards	2019: Member of the Innovation Team of Hunan High-level Talent Gathering Project 2017: National Overseas High-level Talent Introduction Plan 2017: Hunan Science and Technology Innovation Platform and Talent Plan - Outstanding Talent 2017: Hunan Youth Talent 2014: CTSI-SOS Award for Junior Investigator – UCSF 2014: PBBR Award – UCSF 2009: Chinese Academy of Sciences President's Award (Excellence) 2008: Zhu Li Yuehua Scholarship for Doctoral Students, Chinese Academy of Sciences 2007: Hong Kong 'Qiushi' Scholarship

University/Lab Affiliation and Title

Central South University

Faculty

Life Sciences

Academic Background & Achievements

2000.9-2004.7 Bachelor of Science, School of Life Sciences, University of Science and Technology of China
2004.9-2009.12 Doctor of Science, Department of Cell and Molecular Biology, University of Science and Technology of China

Work Experience

2010.4-2016.3 Postdoctoral Researcher, Department of Biochemistry, University of California, San Francisco
2016.4-2017.1 Specialist, Department of Biochemistry, University of California, San Francisco
2017.2-present Researcher, Institute of Precision Molecular Medicine, Xiangya Hospital, Central South University
2019.11-present Director, Clinical Biosample Center, Xiangya Hospital, Central South University

Awards

2019: Member of the Innovation Team of Hunan High-level Talent Gathering Project
2017: National Overseas High-level Talent Introduction Plan
2017: Hunan Science and Technology Innovation Platform and Talent Plan - Outstanding Talent
2017: Hunan Youth Talent
2014: CTSI-SOS Award for Junior Investigator – UCSF
2014: PBBR Award – UCSF
2009: Chinese Academy of Sciences President's Award (Excellence)
2008: Zhu Li Yuehua Scholarship for Doctoral Students, Chinese Academy of Sciences
2007: Hong Kong 'Qiushi' Scholarship

Areas of Focus	Tumor Cell Biology Developmental Cell Biology Epigenetics
Publications	Functional reciprocity of proteins involved in mitosis and endocytosis, Yu H, Li Y, Li L, Huang J, Wang X, Tang R, Jiang Z, Lv L, Chen F, Yu C, Yuan K, 2020 Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate Mid-Blastula Transition events at a low nuclear-cytoplasmic ratio, Strong I, Lei X, Chen F, Yuan K, O’Farrell P, 2020 The kinase activity of Drosophila BubR1 is required for insulin signaling-dependent stem cell maintenance, Tang R, Jiang Z, Chen F, Yu W, Fan K, Tan J, Zhang Z, Liu X, Li P, Yuan K, 2020 Timing the Drosophila Mid-Blastula Transition: a cell cycle-centered view, Yuan K, Seller CA, Shermoen AW, O’Farrell PH, 2016 TALE-light imaging reveals maternally-guided, H3K9me2/3-independent emergence of functional heterochromatin in Drosophila embryos, Yuan K, O’Farrell PH, 2016 Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition, Yuan K, O’Farrell PH, 2015 Illuminating DNA replication during Drosophila development using TALE-lights, Yuan K, Shermoen AW, O’Farrell PH, 2014 Different cyclin-types collaborate to reverse the S phase checkpoint and permit prompt mitosis, Yuan K, Farrell JA, O’Farrell PH, 2012 Illumination of mitotic orchestra during cell division: A polo view, Yuan K, Huang Y, Yao X, 2011 PinX1 is a Novel Microtubule-binding Protein Essential for Accurate Chromosome Segregation, Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw AP, Thomas K, Zhang J, Mann D, Liao J, Jin C, Yao X, 2009 Recruitment of separase to mitotic chromosomes is regulated by Aurora B, Yuan K, Li N, Huo Y, Yan F, Yang Y, Ward T, Jin C, Yao X, 2009 Phospho-regulation of HsCDC14A by polo-like kinase 1 is essential for mitotic progression, Yuan K, Hu H, Guo Z, Fu G, Shaw AP, Hu R, Yao X, 2007

Areas of Focus

Tumor Cell Biology
Developmental Cell Biology
Epigenetics

Publications

Functional reciprocity of proteins involved in mitosis and endocytosis, Yu H, Li Y, Li L, Huang J, Wang X, Tang R, Jiang Z, Lv L, Chen F, Yu C, Yuan K, 2020
Interphase-arrested Drosophila embryos activate zygotic gene expression and initiate Mid-Blastula Transition events at a low nuclear-cytoplasmic ratio, Strong I, Lei X, Chen F, Yuan K, O’Farrell P, 2020
The kinase activity of Drosophila BubR1 is required for insulin signaling-dependent stem cell maintenance, Tang R, Jiang Z, Chen F, Yu W, Fan K, Tan J, Zhang Z, Liu X, Li P, Yuan K, 2020
Timing the Drosophila Mid-Blastula Transition: a cell cycle-centered view, Yuan K, Seller CA, Shermoen AW, O’Farrell PH, 2016
TALE-light imaging reveals maternally-guided, H3K9me2/3-independent emergence of functional heterochromatin in Drosophila embryos, Yuan K, O’Farrell PH, 2016
Cyclin B3 is a mitotic cyclin that promotes the metaphase-anaphase transition, Yuan K, O’Farrell PH, 2015
Illuminating DNA replication during Drosophila development using TALE-lights, Yuan K, Shermoen AW, O’Farrell PH, 2014
Different cyclin-types collaborate to reverse the S phase checkpoint and permit prompt mitosis, Yuan K, Farrell JA, O’Farrell PH, 2012
Illumination of mitotic orchestra during cell division: A polo view, Yuan K, Huang Y, Yao X, 2011
PinX1 is a Novel Microtubule-binding Protein Essential for Accurate Chromosome Segregation, Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw AP, Thomas K, Zhang J, Mann D, Liao J, Jin C, Yao X, 2009
Recruitment of separase to mitotic chromosomes is regulated by Aurora B, Yuan K, Li N, Huo Y, Yan F, Yang Y, Ward T, Jin C, Yao X, 2009
Phospho-regulation of HsCDC14A by polo-like kinase 1 is essential for mitotic progression, Yuan K, Hu H, Guo Z, Fu G, Shaw AP, Hu R, Yao X, 2007

Cancer Cell Signaling Gene Regulation Embryonic Development High-Throughput Screening Genomics Crispr Disease Intervention Molecular Mechanisms Biological Regulation

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