Areas of Focus
- Gene expression regulation in human brain tissue and pathogenic mechanisms of psychiatric diseases
- Algorithm research on large-scale multi-omics data using AI and machine learning for health big data analysis
- Phenomics research related to human brain development and neuropsychiatric genetic diseases
Academic Background & Achievements
- PhD under the guidance of domestic genetics master Zhang Yaping and Jin Li, and international psychiatric genetics authority Elliot Gershon.
- Vice Dean of the School of Life Sciences.
Publications
- Sex-differential DNA methylation and associated regulation networks in human brain implicated in the sex-biased risks of psychiatric disorder, Yan Xia, Rujia Dai, Kangli Wang, Chuan Jiao, Yuchen Xu, Honglei Li, Xi Jing, Yu Chen, Richard Kopp, Gina Giase, Chunling Zhang, Yi Jiang, Chao Chen*, Chunyu Liu*, 2019
- The DGCR5 long noncoding RNA may regulate expression of several schizophrenia-related genes, Qingtuan Meng, Kangli Wang, Tonya Brunetti, Yan Xia, Chuan Jiao, Dominic Fitzgerald, Amber Thomas, Lindsey Jay, Heather Eckart, Kay Grennan, Kevin P. White, The PsychENCODE Consortium, Chao Chen*, Chunyu Liu*, 2018
- The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders, Chao Chen*, Qingtuan Meng, Yan Xia, Chaodong Ding, Lijun Cheng, Preethi Gunaratne, Richard A. Gibbs, Shishi Min, Rujia Dai, Le Wang, Cristian Coarfa, Jeffrey G. Reid, Chunling Zhang, Chuan Jiao, Yi Jiang, Gina Giase, Amber Thomas, Dominic Fitzgerald, Tonya Brunetti, Annie Shieh, Cuihua Xia, Yongjun Wang, Yunpeng Wang, Judith A. Badner, Elliot S. Gershon, Kevin P White, Chunyu Liu*, 2018
- Brain Banks Spur New Frontiers in Neuropsychiatric Research and Strategies for Analysis and Validation, Le Wang, Yan Xia, Yu Chen, Rujia Dai, Wenying Qiu, Chao Chen*, 2019
- Positional effects revealed in Illumina Methylation Array and the impact on analysis, Chuan Jiao, Zhang C, Dai R, Xia Yan, Wang Kangli, Giase Gina, Chen Chao*, Liu Chunyu*, 2018
- BrainEXP: a database featuring with spatiotemporal expression variations and co-expression organizations in human brains, Chuan Jiao, Lingling Huang, Rujia Dai, Yu Wei, Cuihua Xia, Jiacheng Dai, Yan Xia, Shunan Zhao, Liu Yi, Qingtuan Meng, Kangli Wang, Chunyu Liu*, Chao Chen*, 2019
- Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia, C Chen, Zhang C, Cheng L, Reilly JL, Bishop JR, Sweeney JA, Chen H-Y, Gershon ES, Liu C, 2014
- Two gene co-expression modules differentiate psychotics and controls, Chao Chen, L Cheng, K Grennan, F Pibiri, C Zhang, J A Badner, Members of the Bipolar Disorder Genome Study (BiGS) Consortium, E S Gershon and C Liu, 2013
Awards
- Charles J. Epstein Award (2017, 2018)
- Hugh Gurling Award (2016, 2018)
- Outstanding Presentation Award from the North American Chinese Genetics Association (2017, 2018)
