Professor | Liang Li | Asia Growth Partners

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Name	Liang Li
Contact Information	liliang@smu.edu.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Liang Li

Contact Information

liliang@smu.edu.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	Southern Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2003 - Bachelor's degree in Medical Experimental Technology: First Military Medical University 2006 - Master's degree in Cell Biology: First Military Medical University 2009 - PhD in Cell Biology: Southern Medical University 2006 - Awarded 'Outstanding Graduate Student of Nanyue' 2009 - Awarded 'Outstanding Doctoral Dissertation of Southern Medical University'
Work Experience	2006-present - Southern Medical University - Associate Professor in Medical Genetics 2015-2016 - The Ohio State University - Visiting Scholar at the Center for Pharmacogenomics
Awards	2007 - Outstanding Communist Party Member of the Basic Medical College, Southern Medical University 2009 - Second Prize for Teaching Excellence, Southern Medical University 2013 - Guangzhou 'Pearl River Science and Technology New Star' 2014 - Selected for the First 'Outstanding Young Teacher Training Program' of Southern Medical University

University/Lab Affiliation and Title

Southern Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2003 - Bachelor's degree in Medical Experimental Technology: First Military Medical University
2006 - Master's degree in Cell Biology: First Military Medical University
2009 - PhD in Cell Biology: Southern Medical University
2006 - Awarded 'Outstanding Graduate Student of Nanyue'
2009 - Awarded 'Outstanding Doctoral Dissertation of Southern Medical University'

Work Experience

2006-present - Southern Medical University - Associate Professor in Medical Genetics
2015-2016 - The Ohio State University - Visiting Scholar at the Center for Pharmacogenomics

Awards

2007 - Outstanding Communist Party Member of the Basic Medical College, Southern Medical University
2009 - Second Prize for Teaching Excellence, Southern Medical University
2013 - Guangzhou 'Pearl River Science and Technology New Star'
2014 - Selected for the First 'Outstanding Young Teacher Training Program' of Southern Medical University

Areas of Focus	Molecular basis diagnosis and molecular diagnosis of genetic diseases Pharmacogenetics and pharmacogenomics Identification and mechanism analysis of regulatory SNPs
Publications	Transcription Factors and ncRNAs Associated with CYP3A Expression in Human Liver and Small Intestine Assessed with Weighted Gene Co-Expression Network Analysis., Huang H, Zhang S, Wen X, Sadee W, Wang D, Yang S, Li L, 2022 Genomewide association study identifies a novel variant associated with tacrolimus trough concentration in Chinese renal transplant recipients., Yang S, Jiang H, Li C, Lu H, Li C, Ye D, Qi H, Xu W, Bao X, Maseko N, Zhang S, Shao R, Li L, 2022 Trans-eQTLs of the CYP3A4 and CYP3A5 associated with tacrolimus trough blood concentration in Chinese renal transplant patients., Lu H, Jiang H, Yang S, Li C, Li C, Shao R, Zhang P, Wang D, Liu Z, Qi H, Cai Y, Xu W, Bao X, Wang H, Li L, 2022 Functional CYP3A variants affecting tacrolimus trough blood concentrations in Chinese renal transplant recipients., Chen D, Lu H, Sui W, Li L, Xu J, Yang T, Yang S, Zheng P, Chen Y, Chen J, Xue W, Li Q, Zheng Q, Ye D, Sadee W, Wang D, Qian W, Lai L, Li C, Li L, 2021 Partial thyroxine‑binding globulin deficiency in a family with coding region mutations in the TBG gene., Chen LD, Lu HJ, Gan YL, Pang SW, Zheng Q, Ye DM, Huang XY, Qi HN, Xu WB, Wen XZ, Li LH, Li L, 2020 Impact of UGT2B7 and ABCC2 genetic polymorphisms on mycophenolic acid metabolism in Chinese renal transplant recipients., Li LQ, Chen DN, Li CJ, Li QP, Chen Y, Fang P, Zheng P, Lu HJ, Ye DM, Wan HY, Li J, Li L, 2018 Evaluation and comparison of three assays for molecular detection of spinal muscular atrophy., Li L, Zhou WJ, Fang P, Zhong ZY, Xie JS, Yan TZ, Zeng J, Tan XH, Xu XM, 2017 Regulatory Variants Modulate Protein Kinase C α (PRKCA) Gene Expression in Human Heart., Li L, Zhang L, Binkley PF, Sadee W, Wang D, 2017 Tacrolimus in preventing transplant rejection in Chinese patients--optimizing use., Li CJ, Li L, 2015 Molecular characterization and copy number of SMN1, SMN2 and NAIP in Chinese patients with spinal muscular atrophy and unrelated healthy controls., Fang P, Li L, Zeng J, Zhou WJ, Wu WQ, Zhong ZY, Yan TZ, Xie JS, Huang J, Lin L, Zhao Y, Xu XM, 2015 Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR Genetic Polymorphisms on Tacrolimus Metabolism in Chinese Renal Transplant Recipients., Li CJ, Li L, Lin L, Jiang HX, Zhong ZY, Li WM, Zhang YJ, Zheng P, Tan XH, Zhou L, 2014 Tacrolimus dosing in Chinese renal transplant recipients: a population-based pharmacogenetics study., Li L, Li CJ, Zheng L, Zhang YJ, Jiang HX, Si-Tu B, Li ZH, 2011 Rapid, accurate detection of TMPRSS6 gene causative mutations with a high-resolution melting assay., Wu HM, Li L, Yuan XW, Zhou YQ, Xiao QZ, Liu WY, Zhou WJ, Xu XM, 2011 Simultaneous detection of CYP3A5 and MDR1 polymorphisms based on the SNaPshot assay., Li L, Li CJ, Zhang YJ, Zheng L, Jiang HX, Si-Tu B, 2011 Development and evaluation of a reverse dot blot assay for the simultaneous detection of six common Chinese G6PD mutations and one polymorphism., Li L, Zhou YQ, Xiao QZ, Yan TZ, Xu XM, 2008 Rapid, accurate genotyping of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 based on the use of denaturing HPLC., Li L, Mo QH, Xu XM*, 2005

Areas of Focus

Molecular basis diagnosis and molecular diagnosis of genetic diseases
Pharmacogenetics and pharmacogenomics
Identification and mechanism analysis of regulatory SNPs

Publications

Transcription Factors and ncRNAs Associated with CYP3A Expression in Human Liver and Small Intestine Assessed with Weighted Gene Co-Expression Network Analysis., Huang H, Zhang S, Wen X, Sadee W, Wang D, Yang S, Li L*, 2022
Genomewide association study identifies a novel variant associated with tacrolimus trough concentration in Chinese renal transplant recipients., Yang S, Jiang H, Li C, Lu H, Li C, Ye D, Qi H, Xu W, Bao X, Maseko N, Zhang S, Shao R, Li L*, 2022
Trans-eQTLs of the CYP3A4 and CYP3A5 associated with tacrolimus trough blood concentration in Chinese renal transplant patients., Lu H, Jiang H, Yang S, Li C, Li C, Shao R, Zhang P, Wang D, Liu Z, Qi H, Cai Y, Xu W, Bao X, Wang H, Li L*, 2022
Functional CYP3A variants affecting tacrolimus trough blood concentrations in Chinese renal transplant recipients., Chen D, Lu H, Sui W, Li L, Xu J, Yang T, Yang S, Zheng P, Chen Y, Chen J, Xue W, Li Q, Zheng Q, Ye D, Sadee W, Wang D, Qian W, Lai L, Li C, Li L*, 2021
Partial thyroxine‑binding globulin deficiency in a family with coding region mutations in the TBG gene., Chen LD, Lu HJ, Gan YL, Pang SW, Zheng Q, Ye DM, Huang XY, Qi HN, Xu WB, Wen XZ, Li LH*, Li L*, 2020
Impact of UGT2B7 and ABCC2 genetic polymorphisms on mycophenolic acid metabolism in Chinese renal transplant recipients., Li LQ, Chen DN, Li CJ, Li QP, Chen Y, Fang P, Zheng P, Lu HJ, Ye DM, Wan HY, Li J, Li L*, 2018
Evaluation and comparison of three assays for molecular detection of spinal muscular atrophy., Li L, Zhou WJ, Fang P, Zhong ZY, Xie JS, Yan TZ, Zeng J, Tan XH, Xu XM*, 2017
Regulatory Variants Modulate Protein Kinase C α (PRKCA) Gene Expression in Human Heart., Li L, Zhang L, Binkley PF, Sadee W, Wang D*, 2017
Tacrolimus in preventing transplant rejection in Chinese patients--optimizing use., Li CJ, Li L*, 2015
Molecular characterization and copy number of SMN1, SMN2 and NAIP in Chinese patients with spinal muscular atrophy and unrelated healthy controls., Fang P, Li L, Zeng J, Zhou WJ, Wu WQ, Zhong ZY, Yan TZ, Xie JS, Huang J, Lin L, Zhao Y, Xu XM*, 2015
Impact of the CYP3A5, CYP3A4, COMT, IL-10 and POR Genetic Polymorphisms on Tacrolimus Metabolism in Chinese Renal Transplant Recipients., Li CJ, Li L*, Lin L, Jiang HX, Zhong ZY, Li WM, Zhang YJ, Zheng P, Tan XH, Zhou L, 2014
Tacrolimus dosing in Chinese renal transplant recipients: a population-based pharmacogenetics study., Li L, Li CJ*, Zheng L, Zhang YJ, Jiang HX, Si-Tu B, Li ZH, 2011
Rapid, accurate detection of TMPRSS6 gene causative mutations with a high-resolution melting assay., Wu HM, Li L, Yuan XW, Zhou YQ, Xiao QZ, Liu WY, Zhou WJ, Xu XM*, 2011
Simultaneous detection of CYP3A5 and MDR1 polymorphisms based on the SNaPshot assay., Li L, Li CJ*, Zhang YJ, Zheng L, Jiang HX, Si-Tu B, 2011
Development and evaluation of a reverse dot blot assay for the simultaneous detection of six common Chinese G6PD mutations and one polymorphism., Li L, Zhou YQ, Xiao QZ, Yan TZ, Xu XM*, 2008
Rapid, accurate genotyping of alcohol dehydrogenase-1B and aldehyde dehydrogenase-2 based on the use of denaturing HPLC., Li L, Mo QH, Xu XM*, 2005

Genetic Diseases Molecular Diagnosis Pharmacogenetics Pharmacogenomics Regulatory Snps Gwas Gtex Drug Metabolism Personalized Medicine Bioinformatics

Jian Zhang - Southern Medical University

Zhijie Han - Chongqing Medical University

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