Areas of Focus
- Magnetic Resonance Imaging Contrast Agents
- Molecular Imaging Probes
- Biomedical Nanomaterials
- Tumor Targeted Diagnosis and Therapy
Work Experience
- 2008.09-2010.03 - Gunma University, Japan - Postdoctoral Researcher
- 2010.05-2012.04 - University of Adelaide, Australia - Postdoctoral Researcher
- 2012.04-2015.12 - Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences - Associate Researcher, Master's Supervisor
- 2015.12-2019.07 - Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences - Researcher, Doctoral Supervisor
- 2016.07-2019.07 - National Institutes of Health (NIH), USA - Senior Visiting Scholar
- 2019.08-present - Southern Medical University - Professor, Doctoral Supervisor
Academic Background & Achievements
- 1998.09-2002.07 Bachelor: Beijing Technology and Business University, Biochemical Engineering
- 2002.09-2008.07 Doctorate: Institute of Process Engineering, Chinese Academy of Sciences, Biochemical Engineering
- 2004.10-2006.03 Joint Training: Gunma University, Japan, Biomaterials
Publications
- Double-Layered Hollow Mesoporous Cuprous Oxide Nanoparticles for Double Drug Sequential Therapy of Tumors., Zongheng Li, Jing Yang, Bin Ren, Qingdeng Fan, Lin Huang, Shuai Guo, RuiLong Zhou, Sijin Chen, Jie Feng, Chenggong Yan, Xiaoyuan Chen, Zheyu Shen, 2024
- MRI-guided tumor therapy based on synergy of ferroptosis, immunosuppression reversal and disulfidptosis., Shuai Guo, Zongheng Li, Ruilong Zhou, Jie Feng, Lin Huang, Bin Ren, Jiaoyang Zhu, Ya Huang, Guochao Wu, Haobin Cai, Qianqian Zhang, Yushen Ke, Tianwang Guan, Peier Chen, Yikai Xu, Chenggong Yan, Caiwen Ou, Zheyu Shen, 2024
- Ultrathin clay nanoparticles-mediated mutual reinforcement of ferroptosis and cancer immunotherapy., Jianping Liu, Jiezhao Zhan, Ye Zhang, Lin Huang, Jing Yang, Jie Feng, Lingwen Ding, Zheyu Shen, Xiaoyuan Chen, 2024
- Synergistic Glutathione Depletion and STING Activation to Potentiate Dendritic Cell Maturation and Cancer Vaccine Efficacy., Jianping Liu, Ye Zhang, Bowei Yang, Yingbo Jia, Rui-tian Liu, Lingwen Ding, Zheyu Shen, Xiaoyuan Chen, 2024
- A Mesoporous Superparamagnetic Iron Oxide Nanoparticle as a Generic Drug Delivery System for Tumor Ferroptosis Therapy., Jing Yang, Wei Xiong, Lin Huang, Zongheng Li, Qingdeng Fan, Fang Hu, Xiaopin Duan, Junbing Fan, Bo Li, Jie Feng, Yikai Xu, Xiaoyuan Chen, Zheyu Shen, 2024
- Kilogram Scale Facile Synthesis and Systematic Characterization of a Gd-Macrochelate as T1-Weighted Magnetic Resonance Imaging Contrast Agent., Meng Shi, Wei Xiong, Jie Feng, Lihe Wu, Jing Yang, Yudie Lu, Xuanyi Lu, Qingdeng Fan, Hemin Nie, Yunlu Dai, Chenggong Yan, Ye Tian, Zheyu Shen, 2024
- Kilogram-Scale Synthesis of Extremely Small Gadolinium Oxide Nanoparticles as a T1-Weighted Contrast Agent for Magnetic Resonance Imaging., Lihe Wu, Xuanyi Lu, Yudie Lu, Meng Shi, Shuai Guo, Jie Feng, Sugeun Yang, Wei Xiong, Yikai Xu, Chenggong Yan, Zheyu Shen, 2024
- An AND logic gate for magnetic resonance imaging-guided ferroptosis therapy of tumors., Qingdeng Fan, Wei Xiong, Huimin Zhou, Jing Yang, Jie Feng, Zongheng Li, Lihe Wu, Fang Hu, Xiaopin Duan, Bo Li, Junbing Fan, Yikai Xu, Xiaoyuan Chen, Zheyu Shen, 2023
- Tumor-generated reactive oxygen species storm for high-performance ferroptosis therapy., Lin Huang, Jiaoyang Zhu, Wei Xiong, Jie Feng, Jing Yang, Xuanyi Lu, Yudie Lu, Qianqian Zhang, Peiwei Yi, Yanqiu Feng, Shuai Guo, Xiaozhong Qiu, Yikai Xu, Zheyu Shen, 2023
- A strategy of limited-space controlled aggregation for generic enhancement of drug loading capability., Lin Huang, Yudie Lu, Shuai Guo, Jing Yang, Zhiyu Liang, Qianqian Zhang, Peiwei Yi, Yanqiu Feng, Yan Li, Yikai Xu, Xiaozhong Qiu, Jie Feng, Zheyu Shen, 2023
- Facile synthesis of weakly ferromagnetic organogadolinium macrochelates-based T1-weighted magnetic resonance imaging contrast agents., Yudie Lu, Zhiyu Liang, Jie Feng, Lin Huang, Shuai Guo, Peiwei Yi, Wei Xiong, Sijin Chen, Sugeun Yang, Yikai Xu, Yan Li, Xiaoyuan Chen, Zheyu Shen, 2023
- A STING pathway-activatable contrast agent for MRI-guided tumor immunoferroptosis synergistic therapy., Shuai Guo, Wei Xiong, Jiaoyang Zhu, Jie Feng, Ruilong Zhou, Qingdeng Fan, Qianqian Zhang, Zongheng Li, Jing Yang, Huimin Zhou, Peiwei Yi, Yanqiu Feng, Sugeun Yang, Xiaozhong Qiu, Yikai Xu, Zheyu Shen, 2023
- Exceedingly small magnetic iron oxide nanoparticles for T1-weighted magnetic resonance imaging and imaging-guided therapy of tumors., Jing Yang, Jie Feng, Sugeun Yang, Yikai Xu, Zheyu Shen, 2023
- Targeted Magnetic Resonance Imaging/Near-Infrared Dual-Modal Imaging and Ferroptosis/Starvation Therapy of Gastric Cancer with Peritoneal Metastasis., Weihong Guo, Yingxin Ren, Zhian Chen, Guodong Shen, Yudie Lu, Huimin Zhou, Zhenyuan Li, Zhenhao Li, Xuanyi Lu, Guoxin Li, Zheyu Shen, Yanfeng Hu, 2023
- A strategy of Fenton reaction cycloacceleration for high performance ferroptosis therapy initiated by tumor microenvironment remodeling., Lin Huang, Jie Feng, Jiaoyang Zhu, Jing Yang, Wei Xiong, Xuanyi Lu, Sijin Chen, Sugeun Yang, Yan Li, Yikai Xu, Zheyu Shen, 2023
- Cycloacceleration of ferroptosis and calcicoptosis for magnetic resonance imaging-guided colorectal cancer therapy., Shuai Guo, Zongheng Li, Jie Feng, Wei Xiong, Jing Yang, Xuanyi Lu, Sugeun Yang, Yikai Xu, Aiguo Wu, Zheyu Shen, 2022
- Cycloacceleration of reactive oxygen species generation based on exceedingly small magnetic iron oxide nanoparticles for tumor ferroptosis therapy., Huimin Zhou, Xuanyi Lu, Chao Du, Zijian Zhou, Jie Feng, Zhiyu Liang, Yikai Xu, Xiaozhong Qiu, Zheyu Shen, 2022
- Biodegradable and biocompatible exceedingly small magnetic iron oxide nanoparticles for T1-weighted magnetic resonance imaging of tumors., Xuanyi Lu, Huimin Zhou, Zhiyu Liang, Jie Feng, Yudie Lu, Lin Huang, Xiaozhong Qiu, Yikai Xu, Zheyu Shen, 2022
Awards
- Recent 3 years: Listed in the top 2% of global scientists (Elsevier)
- 2021: Ningbo Science and Technology Award, Third Prize
- 2018: Zhejiang Provincial Natural Science Foundation Outstanding Youth Science Fund
- 2017: Ningbo Science and Technology Award, First Prize
- 2017: Ningbo Leading and Top Talent (Second Level)
- 2016: Member of the Youth Innovation Promotion Association, Chinese Academy of Sciences