Areas of Focus
- Relationship between innate immunity and inflammatory diseases
- Innate immune characteristics of the digestive system
- Relationship between metabolism and inflammatory immunity
Academic Background & Achievements
- 1999.9-2003.7 Bachelor: First Military Medical University, Medical Laboratory Technology
- 2003.9-2006.7 Master: First Military Medical University, Immunology
- 2008.9-2012.7 Doctorate: Southern Medical University, Immunology
Publications
- Macrophage scavenger receptor 1 contributes to pathogenesis of fulminant hepatitis via neutrophil mediated complement activation., Tang Y, Li H, Li J, Liu Y, Li Y, Zhou J, Zhou Jia, Lu X, Zhao W, Hou J, Wang XY, Chen Z*, Zuo D*., 2018
- Scavenger receptor SRA/CD204 restrains T cell activation and protects against concanavalin A-induced hepatic injury., Zuo D, Yu X, Guo C, Yi H, Lu X, Lv ZP, Subjeck JR, Zhou H, Sanyal AJ, Chen Z, Wang XY., 2013
- Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis., Dong L, Jiang H, Chen K, Xie J, An Q, Deng F, Sun Z, Liu Y, Zhou J, Zhang L, Lu X, Wang M, Chen Z*, Zou X*, Zuo D*., 2022
- Mannan-Binding Lectin via Interaction With Cell Surface Calreticulin Promotes Senescence of Activated Hepatic Stellate Cells to Limit Liver Fibrosis Progression., Luo J, Li L, Chang B, Zhu Z, Deng F, Hu M, Yu Y, Lu X, Chen Z, Zuo D*, Zhou J*., 2022
- Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release., Chen Y, Hu M, Deng F, Wang P, Lin J, Zheng Z, Liu Y, Dong L, Lu X, Chen Z, Zhou J, Zuo D*., 2021
- Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1., Xie M, Yin Y, Chen L, Yin A, Liu Y, Liu Y, Dong L, Lai Q, Zhou J, Zhang L, Xu M, Chen Z, Zuo D*., 2020
- Gender difference in the effect of omega-3 polyunsaturated fatty acids on acetaminophen-induced acute liver failure., Liu Y, Chen Y, Yin A, Xie X, Yin Y, Liu Y, Dong L, Zhou J, Lu X, Chen Z*, Wen K*, and Zuo D*., 2020
- Mannan-binding lectin attenuates acetaminophen-induced hepatotoxicity by regulating CYP2E1 expression via ROS-dependent JNK/SP1 pathway., Li H, Liu Y, Li J, Liu Y, Dong L, Yin Y, Yu Y, Zhou J, Zhang L, Lu X, Chen Z*, Zuo D*., 2019
- Mannan-binding lectin suppresses growth of hepatocellular carcinoma by regulating hepatic stellate cell activation via the ERK/COX-2/PGE2 pathway., Li J, Li H, Yu Y, Liu Y, Liu Y, Ma Q, Zhang L, Lu X, Wang XY, Chen Z*, Zuo D*, Zhou J*., 2018
- Mannan-binding lectin, a serum collectin, suppresses T-cell proliferation via direct interaction with cell surface calreticulin and inhibition of proximal T-cell receptor signaling., Zhao N, Wu J, Xiong S, Zhang L, Lu X, Chen S, Wu Q, Wang H, Liu Y, Chen Z*, Zuo D*., 2017
Awards
- 2016: Guangdong Special Support Plan 'Hundred, Thousand, and Ten Thousand Talents Project' Young Top Talent, Guangdong Provincial Party Committee Organization Department
- 2013: Guangdong Province Higher Education Outstanding Young Teacher Training Program, Guangdong Provincial Department of Education