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Zhou Xinying
Laboratory Medicine and Biotechnology
Southern Medical University
Guangdong
Language: English, Chinese
Interferon
Gene Regulation
Tuberculosis
Immune Activity
Antigen Presentation
Cell Signaling
Pathway Regulation
Infection
Immunology
Mycobacterium
Areas of Focus
- Tuberculosis Infection Immunity
Academic Background & Achievements
- 2005.09-2009.07 Bachelor: Hunan University of Science and Technology, Bioengineering
- 2009.09-2012.07 Master: South China University of Technology, Biochemistry and Molecular Biology
- 2012.10-2016.09 PhD: Erasmus University Rotterdam, Biomedical Sciences
Publications
- GSK-3α/β Activity Negatively Regulates MMP-1/9 Expression to Suppress Mycobacterium tuberculosis Infection., Zhou X#, Lie L#, Liang Y, Xu H, Zhu B, Huang Y, Zhang L, Zhang Z, Li Q, Wang Q, Han Z, Huang Y, Liu H, Hu S, Zhou C, Wen Q, Ma L*., 2022
- MxA suppresses TAK1-IKKα/β-NF-κB mediated inflammatory cytokine production to facilitate Mycobacterium tuberculosis infection., Zhou X#, Zhang L#, Lie L, Zhang Z, Zhu B, Yang J, Gao Y, Li P, Huang Y, Xu H, Li Y, Du X, Zhou C, Hu S, Wen Q, Zhong X, Ma L*., 2020
- Interferon regulatory factor 1 eliminates mycobacteria by suppressing p70 S6 kinase via mechanistic target of rapamycin signaling., Zhou X#, Yang J#, Zhang Z, Zhang L, Lie L, Zhu B, Gao Y, Du X, Huang Y, Wang R, Liu H, Li Y, Hu S, Zhou C, Wen Q, Pan Q, Ma L*., 2019
- Different signaling pathways define Different interferon-stimulated gene expression during mycobacteria infection in macrophages., Zhou X#, Yang J#, Zhang Z, Zhang L, Zhu B, Lie L, Huang Y, Ma R, Zhou C, Hu S, Wen Q, Pan Q, Ma L*., 2019
- Hepatitis E virus infects neurons and brains., Zhou X#, Huang F#*, Xu L, Lin Z, de Vrij FMS, Ayo-Martin AC, van der Kroeg M, Zhao M, Yin Y, Wang W, Cao W, Wang Y, Kushner SA, Marie Peron J, Alric L, de Man RA, Jacobs BC, van Eijk JJ, Aronica EMA, Sprengers D, Metselaar HJ, de Zeeuw CI, Dalton HR, Kamar N, Peppelenbosch MP, Pan Q*., 2017
- Rapamycin and everolimus facilitate hepatitis E virus replication: revealing a basal defense mechanism of PI3K-PKB-mTOR pathway., Zhou X, Wang Y, Metselaar HJ, Janssen HL, Peppelenbosch MP, Pan Q*., 2014
- Disparity of basal and therapeutically activated interferon signalling in constraining hepatitis E virus infection., Zhou X, Xu L, Wang W, Watashi K, Wang Y, Sprengers D, de Ruiter PE, van der Laan LJ, Metselaar HJ, Kamar N, Peppelenbosch MP, Pan Q*., 2016
- Requirement of the eukaryotic translation initiation factor 4F complex in hepatitis E virus replication., Zhou X, Xu L, Wang Y, Wang W, Sprengers D, Metselaar HJ, Peppelenbosch MP, Pan Q*., 2015
- Epidemiology and management of chronic hepatitis E infection in solid organ transplantation: a comprehensive literature review., Zhou X, de Man RA, de Knegt RJ, Metselaar HJ, Peppelenbosch MP, Pan Q*., 2013
Awards
- 2016: Young Investigator Award, 51st The International Liver Congress, Barcelona, Spain
- 2015: Young Investigator Award, 50th The International Liver Congress, Vienna, Austria
- 2014: Young Investigator Award, 49th The International Liver Congress, London, England
- 2017: Guangdong Province Higher Education Pearl River Scholar 'Young Scholar'
