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Xu Chenguang
Laboratory Medicine and Biotechnology
Southern Medical University
Guangdong
Language: Chinese, English
Car-T
Signal Activation
Regulation Mechanisms
Immunotherapy
Biotechnology
Genetic Engineering
Cell Therapy
Cancer Treatment
Immune Response
Therapeutic Strategies
Areas of Focus
- Research on CAR-T signal activation and regulation mechanisms
- Research on new CAR designs and strategies
Academic Background & Achievements
- 2005.9-2009.7 Bachelor's in Biotechnology: Henan Agricultural University
- 2009.9-2012.7 Master's in Genetics: Capital Normal University
- 2012.9-2018.1 PhD in Biology: Tsinghua University
Publications
- Mechanical force determines chimeric antigen receptor microclustering and signaling, Qiu Y, Xiao QY, Wang YC, Cao YC, Wang J, Wan ZP, Chen XJ, Liu WL, Ma L, Xu CG, 2024
- Imaging PIP2 and BCR microclusters in B cell immunological synapse, Qiu Y, Liu S, Ji X, Gao J, Liu WL, Xu CG, 2023
- New strategy for promoting vascularization in tumor spheroids in a microfluidic assay, Wan Z, Floryan MA, Coughlin MF, Zhang S, Zhong AX, Shelton SE, Wang X, Xu CG, Barbie DA, Kamm RD, 2023
- A PI(4,5)P2 derived “gasoline engine model” for the sustained B cell receptor activation, Xu CG, Wan ZP, Shaheen S, Wang J, Yang ZY, Liu WL, 2019
- MARCKS regulates tonic and chronic active B cell receptor signaling, Xu CG, Fang Y, Yang ZY, Jing YK, Zhang YH, Liu CH, Liu WL, 2019
- A PIP2 derived amplification loop fuels the sustained initiation of B cell activation, Xu CG, Xie HY, Guo XD, Gong HP, Liu L, Qi H, Xu CQ, Liu WL, 2017
