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Xialin Du
Laboratory Medicine and Biotechnology
Southern Medical University
Guangdong
Language: Chinese, English
Tuberculosis
Immunity
Molecular Regulation
Infection
Mechanisms
Ferroptosis
Breast Cancer
Metastasis
Inhibition
Research
Areas of Focus
- Molecular regulatory mechanisms of anti-tuberculosis infection immunity
- Mechanisms of ferroptosis inhibition in breast cancer metastasis
Work Experience
- 2021.07-2023.12 - Sun Yat-sen University Cancer Prevention and Treatment Center - Postdoctoral Researcher
Academic Background & Achievements
- 2012.9-2016.7 Bachelor in Biotechnology: Southern Medical University
- 2016.9-2021.7 PhD in Immunology: Southern Medical University
- 2021.07-2023.12 Postdoctoral in Oncology: Sun Yat-sen University Cancer Prevention and Treatment Center
Publications
- The E3 ligase HERC5 promotes antimycobacterial responses in macrophages by ISGylating the phosphatase PTEN, Du, X., Sheng, J., Chen, Y., He, S., Yang, Y., Huang, Y., Fu, Y., Lie, L., Han, Z., Zhu, B., Liu, H., Wen, Q., Zhou, X., Zhou, C., Hu, S. and Ma, L., 2023
- Vitamin B6 prevents excessive inflammation by reducing accumulation of sphingosine-1-phosphate in a sphingosine-1-phosphatelyase-dependent manner, Du, X.; Yang, Y.; Zhan, X.; Huang, Y.; Fu, Y.; Zhang, Z.; Liu, H.; Zhang, L.; Li, Y.;Wen, Q.; Zhou, X.; Zuo, D.; Zhou, C.; Li, L.; Hu, S.; Ma, L., 2020
- NLRC3 negatively regulates CD4+ T cells and impacts protective immunity during Mycobacterium tuberculosis infection, Hu, S.; Du, X.; Huang, Y.; Fu, Y.; Yang, Y.; Zhan, X.; He, W.; Wen, Q.; Zhou, X.; Zhou,C.; Zhong, X.P.; Yang, J.; Xiong, W.; Wang, R.; Gao, Y.; Ma, L., 2018
- IL-17 Production of Neutrophils Enhances Antibacteria Ability but Promotes Arthritis Development During Mycobacterium tuberculosis Infection, Hu, S.; He, W.; Du, X.; Yang, J.; Wen, Q.; Zhong, X.P.; Ma, L., 2017
- Novel Function of Cyclooxygenase-2: Suppressing Mycobacteria by Promoting Autophagy via the Protein Kinase B/Mammalian Target of Rapamycin Pathway, Xiong W, Wen Q, Du X, Wang J, He W, Wang R, Hu S, Zhou X, Yang J, Gao Y, Ma L., 2018
- Vitamin B5 reduces bacterial growth via regulating innate immunity and adaptive immunity in mice infected with mycobacterium tuberculosis, He W, Hu S, Du X, Wen Q, Zhong XP, Zhou X, Zhou C, Xiong W, Gao Y, Zhang S, Wang R, Yang J, Ma L., 2018
- Vitamin B1 Helps to Limit Mycobacterium tuberculosis Growth via Regulating Innate Immunity in a Peroxisome Proliferator-Activated Receptor-γ-Dependent Manner, Hu S, He W, Du X, Huang Y, Fu Y, Yang Y, Hu C, Li S, Wang Q, Wen Q, Zhou X, Zhou C, Zhong XP, Ma L., 2018
Awards
- 2021: Outstanding Graduate Student, Southern Medical University
- 2020: National Scholarship for Doctoral Students, Ministry of Education of the People's Republic of China
- 2020: Outstanding Graduate Student, Southern Medical University
- 2019: Outstanding Graduate Student, Southern Medical University
