1994 - Present: Research in pathogen infection, innate immunity, and inflammation
2007: Ministry of Education Specially Appointed Professor
2009: National Outstanding Youth Talent Program
2012: Tan Jiazhen Life Science Innovation Award
Research
Pathogen infection Innate immunity and inflammation microRNA and immunity
Human cytomegalovirus reprogrammes haematopoietic progenitor cells into immunosuppressive monocytes to achieve latency, Zhu D, Pan C, Sheng J, Liang H, Bian Z, Liu Y, Trang P, Wu J, Liu F, Zhang CY, Zen K, 2018
H5N1 influenza virus-specific miRNA-like small RNA increases cytokine production and mouse mortality via targeting poly(rC) binding protein 2, Li X, Fu Z, Liang H, Wang Y, Qi X, Ding M, Sun X, Zhou Z, Huang Y, Gu H, Li L, Chen X, Li D, Zhao Q, Liu F, Wang H, Wang J, Zen K, Zhang CY, 2018
Nuclear miR-122 directly regulates the biogenesis of cell survival oncomiR miR-21 at the posttranscriptional level, Wang D, Sun X, Wei Y, Liang H, Yuan M, Jin F, Chen X, Liu Y, Zhang CY, Li L, Zen K, 2018
Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23, Wei Y, Wang D, Jin F, Bian Z, Li L, Liang H, Li M, Shi L, Pan C, Zhu D, Chen X, Hu G, Liu Y, Zhang CY, Zen K, 2017
Human Cytomegalovirus miR-UL148D Facilitates Latent Viral Infection by Targeting Host Cell Immediate Early Response Gene 5, Pan C, Zhu D, Wang Y, Li L, Li D, Liu F, Zhang CY, Zen K, 2016
Hepatitis B virus-human chimeric transcript HBx-LINE1 promotes hepatic injury via sequestering cellular microRNA-122, Liang H, Wang N, Wang Y, Wang F, Fu Z, Yan X, Zhu H, Diao W, Ding Y, Chen X, Zhang CY, Zen K, 2015
CD47 deficiency ameliorates autoimmune nephritis in Fas(lpr) mice by suppressing IgG autoantibody production, Shi L, Bian Z, Chen CX, Guo YN, Lv Z, Zeng C, Liu Z, Zen K, Liu Y, 2015
Role of myeloid-derived suppressor cells in glucocorticoid-mediated amelioration of focal segmental glomerulosclerosis, Li L, Zhang T, Diao, W, Jin F, Shi L, Meng J, Liu H, Zhang J, Zeng C, Zhang M, Liang S, Liu Y, Zhang CY, Liu ZH, Zen K, 2015
Protein Tyrosine Phosphatase 1B Impairs Diabetic Wound Healing Through Vascular Endothelial Growth Factor Receptor 2 Dephosphorylation, Zhang J, Li L, Li J, Liu Y, Zhang CY, Zhang Y, Zen K, 2014
Honeysuckle-encoded atypical microRNA2911 directly targets influenza A viruses, Zhou Z, Li X, Liu J, Dong L, Chen Q, Liu J, Kong H, Zhang Q, Qi X, Hou D, Zhang L, Zhang G, Liu Y, Zhang Y, Li J, Wang J, Chen X, Wang H, Zhang J, Chen H, Zen K, Zhang CY, 2014
Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth, Yin Y, Cai X, Chen X, Liang H, Zhang Y, Li J, Wang Z, Chen X, Zhang W, Yokoyama S, Wang C, Li L, Li L, Hou D, Dong L, Xu T, Hiroi T, Yang F, Ji H, Zhang J, Zen K, Zhang CY, 2014
Microvesicle-mediated delivery of transforming growth factor β1 siRNA for the suppression of tumor growth in mice, Zhang Y, Li L, Yu J, Zhu D, Zhang Y, Li X, Gu H, Zhang CY, Zen K, 2014
MicroRNA-17/20a -/106a modulate macrophage inflammatory responses through targeting signal- regulatory protein α, Zhu D, Pan C, Li L, Bian Z, Lv Z, Shi L, Zhang J, Li D, Gu H, Zhang CY, Liu Y, Zen K, 2013
Inflammation-induced proteolytic processing of the SIRPα cytoplasmic ITIM in neutrophils propagates a proinflammatory state, Zen K, Guo Y, Bian Z, Lv Z, Zhu D, Ohnishi H, Matozaki T, Liu Y, 2013
Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA, Zhang L, Hou D, Chen X, Li D, Zhu L, Zhang Y, Li J, Bian Z, Liang X, Cai X, Yin Y, Wang C, Zhang T, Zhu D, Zhang D, Xu J, Chen Q, Ba Y, Liu J, Wang Q, Chen J, Wang J, Wang M, Zhang Q, Zhang J, Zen K, Zhang CY, 2012
Cleavage of the CD11b extracellular domain by the leukocyte serprocidins is critical for neutrophil detachment during chemotaxis, Zen K, Guo YL, Li LM, Bian Z, Zhang CY, Liu Y, 2011
Role of miR-150-targeting c-Myb in colonic epithelial disruption during dextran sulphate sodium-induced murine experimental colitis and human ulcerative colitis, Bian Z, Li L, Cui J, Zhang H, Liu Y, Zhang CY, Zen K, 2011
Mouse miRNA-709 directly regulates miRNA-15a/16-1 biogenesis at the posttranscriptional level in the nucleus: evidence for a microRNA hierarchy system, Tang R, Li L, Zhu D, Hou D, Cao T, Gu H, Zhang J, Chen J, Zhang CY, Zen K, 2011
Identification of mouse liver mitochondria -associated miRNAs and their potential biological functions, Bian Z, Li LM, Tang R, Hou DX, Chen X, Zhang CY, Zen K, 2010
Secreted monocytic miR-150 enhances targeted endothelial cell migration, Zhang Y, Liu D, Chen X, Li J, Li L, Bian Z, Sun F, Lu J, Yin Y, Cai X, Sun Q, Wang K, Ba Y, Wang Q, Wang D, Yang J, Liu P, Xu T, Yan Q, Zhang J, Zen K, Zhang CY, 2010
Uncoupling protein-2 negatively regulates polymorphonuclear leukocytes chemotaxis via modulating [Ca2+] influx, Liu DQ, Guo YL, Bian Z, Chen YY, Chen X, Liu Y, Zhang CY, Zen K, 2010
Role of junctional adhesion molecule-like protein in mediating monocyte transendothelial migration, Guo YL, Bai R, Chen CX, Liu DQ, Liu Y, Zhang CY, Zen K, 2009
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases, Chen X, Ba Y, Ma L, Cai X, Yin Y, Wang K, Guo J, Zhang Y, Chen J, Guo X, Li Q, Li X, Wang W, Zhang Y, Wang J, Jiang X, Xiang Y, Xu C, Zheng P, Zhang J, Li R, Zhang H, Shang X, Gong T, Ning G, Wang J, Zen K, Zhang J, Zhang CY, 2008
