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Zichun Hua
huazc@nju.edu.cn
Chinese, English
Jiangsu

Academic Information

Nanjing University
Life Sciences
  • National Technological Invention Second Prize (2013): Detail
  • National Natural Science Second Prize (2000): Detail
  • Jiangsu Province First Prize (2004, 2011, 2014, 2017): Detail
  • Ministry of Education First Prize (1998, 2018, 2023): Detail
  • National Disruptive Technology Innovation Competition Finalist Award: Detail
  • China Patent Excellence Award: Detail
  • China International Industry Fair Silver Award: Detail
  • China Industry-University-Research Cooperation Innovation Achievement First Prize: Detail
  • Invention and Entrepreneurship Achievement Award First Prize (2 items): Detail
  • China Overseas Chinese Contribution Award - Innovation Achievement Award: Detail
  • First Jiangsu Innovation and Entrepreneurship Competition First Prize: Detail

Research

Intelligent live microbial drugs
New methods of tumor immunotherapy
Peptide and protein engineering
Protein structure and function
New functions of cell apoptosis signaling and related new drug development
  • Inflammation-oriented montmorillonite adjuvant enhanced oral delivery of anti-TNF-α nanobody against inflammatory bowel disease, Baolian Huang, Te Yin, Shuilian Fu, Lina Liu, Chen Yang, Lulu Zhou, Xing Liu, Hongqin Zhuang, Zhiting Cao, Zichun Hua, 2024
  • Dual-Engineered Macrophage-Microbe Encapsulation for Metastasis Immunotherapy, Leyang Wu, Liyuan Qiao, Shuhui Zhang, Jiahui Qiu, Zengzheng Du, Ying Sun, Xiaoyao Chang, Lin Li, Chenyang Li, Xinyue Qiao, Xingpeng Yin, Zichun Hua, 2024
  • Programmable Bacteria with Dynamic Virulence Modulation System for Precision Antitumor Immunity, Leyang Wu, Lin Li, Liyuan Qiao, Chenyang Li, Shuhui Zhang, Xingpeng Yin, Zengzheng Du, Ying Sun, Jiahui Qiu, Xiaoyao Chang, Bohao Wang, Zichun Hua, 2024
  • Camouflaging attenuated Salmonella by cryo-shocked macrophages for tumor-targeted therapy, Leyang Wu, Zengzheng Du, Lin Li, Liyuan Qiao, Shuhui Zhang, Xingpeng Yin, Xiaoyao Chang, Chenyang Li, Zichun Hua, 2024
  • A bacteria-based system expressing anti-TNF-α nanobody for enhanced cancer immunotherapy, Lina Liu, Xing Liu, Wenjie Xin, Lulu Zhou, Baolian Huang, Chao Han, Zhiting Cao, Zichun Hua, 2023
  • Tannic acid assisted anti-TNF-α nanobody assembly modulating the epithelial barrier dysregulation of allergic rhinitis, Shuilian Fu, Zhiting Cao, Baolian Huang, Te Yin, Chujun Huang, Zhiqian Bi, Yingying Yao, Xiaoyao Chang, Hongqin Zhuang, Zichun Hua, 2023
  • Neutrophil-Mediated Tumor-Targeting Delivery System of Oncolytic Bacteria Combined with ICB for Melanoma Lung Metastasis Therapy, Lina Liu, Wenjie Xin, Qiang Li, Baolian Huang, Te Yin, Siqi Hua, Chen Yang, Chen Chen, Chao Han, Zichun Hua, 2023
  • Oncogenic KRAS effector USP13 promotes metastasis in non-small cell lung cancer through deubiquitinating b-catenin, Yanguan Guo, Jiaxin Tian, Yongjian Guo, Cong Wang, Congcong Chen, Songwang Cai, Wenliang Yu, Binghe Sun, Jin Yan, Zhonghua Li, Jun Fan, Qi Qi, Dongmei Zhang, Weilin Jin, Zichun Hua, Guo Chen, 2023
  • Macrophage-mediated tumor-targeted delivery of engineered Salmonella typhimurium VNP20009 in anti–PD1 therapy against melanoma, Leyang Wu, Lin Li, Shufeng Li, Lina Liu, Wenjie Xin, Chenyang Li, Xingpeng Yin, Xuebo Xu, Feifei Bao, Zichun Hua, 2022
  • Bacterially mediated drug delivery and therapeutics: Strategies and advancements, Leyang Wu, Feifei Bao, Lin Li, Xingpeng Yin, Zichun Hua, 2022
  • RIP3 deficiency attenuated hepatic stellate cell activation and liver fibrosis in schistosomiasis through JNK-cJUN/Egr1 downregulation, Li-Jun Song, Xu-Ren Yin, Sheng-Wen Guan, Hong Gao, Pan-Pan Dong, Cong-Jin Mei, Ying-Ying Yang, Ying Zhang, Chuan-Xin Yu, Zi-Chun Hua, 2022
  • Combined Cellular Thermometry Reveals That Salmonella typhimurium Warms Macrophages by Inducing a Pyroptosis-like Phenotype, Leyang Wu, Feng Chen, Xiaoyao Chang, Lin Li, Xingpeng Yin, Can Li, Fangxu Wang, Chenyang Li, Qin Xu, Hongqin Zhuang, Ning Gu, Zi-Chun Hua, 2022
Keywords
Microbial Drugs Tumor Immunotherapy Peptide Engineering Protein Structure Cell Apoptosis Drug Development Biotechnology Nanomedicine Cancer Therapy Biopharmaceuticals
Related Professors
Hua Gu - Tongji University
Area of Focus
Biopharmaceuticals | Antitumor | Autoimmune Diseases | Drug Development | Molecular Biology | Angiogenesis | Tumor | Regulation | Molecular Mechanisms | Therapeutics
Rongxiu Li - Shanghai Jiao Tong University
Area of Focus
Biopharmaceuticals | Drug Design | Research Development | Purification Technologies | Biomanufacturing | Scale-Up Studies | Biological Engineering | Biotechnology | Scientific Research | Pilot Studies
Jianming Zhu - Huazhong University of Science and Technology
Area of Focus
Biopharmaceuticals | Innovation | Drug Development | Biotechnology | Pharmaceutical Industry | Healthcare | Medical Research | Economic Impact | Policy Research | Industry Development
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