Professor | Yajun Jiang | Asia Growth Partners

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Name	Yajun Jiang
Contact Information	yajunjiang@nju.edu.cn
Language ability	Chinese, English
Province	Jiangsu

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Name

Yajun Jiang

Contact Information

yajunjiang@nju.edu.cn

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Life Sciences
Academic Background & Achievements	2001.9-2005.6 Bachelor: Nanjing University, School of Life Sciences 2005.9-2012.1 Doctorate: Shanghai Institute of Life Sciences, Chinese Academy of Sciences
Work Experience	2012.9-2015.7 Rutgers University, Department of Chemistry and Chemical Biology - Postdoctoral Researcher 2015.8-2017.7 University of Minnesota, Department of Biochemistry, Molecular Biology, and Biophysics - Postdoctoral Researcher 2017.8-2021.1 St. Jude Children's Research Hospital, Department of Structural Biology - Postdoctoral Researcher 2021.2- Nanjing University, School of Life Sciences - Distinguished Researcher 2021.2- Nanjing University, Institute of Chemistry and Biomedical Innovation - Distinguished Researcher
Awards	National Youth Talent Program

University/Lab Affiliation and Title

Nanjing University

Faculty

Life Sciences

Academic Background & Achievements

2001.9-2005.6 Bachelor: Nanjing University, School of Life Sciences
2005.9-2012.1 Doctorate: Shanghai Institute of Life Sciences, Chinese Academy of Sciences

Work Experience

2012.9-2015.7 Rutgers University, Department of Chemistry and Chemical Biology - Postdoctoral Researcher
2015.8-2017.7 University of Minnesota, Department of Biochemistry, Molecular Biology, and Biophysics - Postdoctoral Researcher
2017.8-2021.1 St. Jude Children's Research Hospital, Department of Structural Biology - Postdoctoral Researcher
2021.2- Nanjing University, School of Life Sciences - Distinguished Researcher
2021.2- Nanjing University, Institute of Chemistry and Biomedical Innovation - Distinguished Researcher

Awards

National Youth Talent Program

Areas of Focus	Molecular mechanisms of neurodegenerative diseases Dynamic working principles of protein machines Application of ultra-large molecular biological NMR technology
Publications	Structural basis for client recognition and activity of Hsp40 chaperones, Jiang Y, Rossi P, Kalodimos CG, 2019 Confirmation for conformational selection, Jiang Y, Kalodimos CG, 2018 Automatic methyl assignment in large proteins by the MAGIC algorithm, Monneau YR, Rossi P, Bhaumik A, Huang C, Jiang Y, Saleh T, Xie T, Xing Q, Kalodimos CG, 2017 NMR Studies of Large Proteins, Jiang Y, Kalodimos CG, 2017 TDP-35 sequesters TDP-43 into cytoplasmic inclusions through binding with RNA, Che MX, Jiang LL, Li HY, Jiang YJ, Hu HY, 2015 Aggregation of polyglutamine-expanded ataxin-3 sequesters its specific interacting partners into inclusions: Implication in a loss-of-function pathology, Yang H, Li JJ, Liu S, Zhao J, Jiang YJ, Song AX, Hu HY, 2014 Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin, Gao YG, Yang H, Zhao J, Jiang YJ, Hu HY, 2014 Structural basis for recognition of the third SH3 domain of Full-length R85(R85FL)/Ponsin by Ataxin-7, Jiang YJ, Zhou CJ, Zhou ZR, Wu M, and Hu HY, 2013 Interaction with Polyglutamine-expanded Huntingtin Alters Cellular Distribution and RNA Processing of Huntingtin Yeast Two-hybrid Protein A (HYPA), Jiang YJ, Che MX, Yuan JQ, Xie YY, Yan XZ, Hu HY, 2011 Aggregation of the 35-kDa fragment of TDP-43 causes formation of cytoplasmic inclusions and alteration of RNA processing, Che MX, Jiang YJ, Xie YY, Jiang LL, Hu HY, 2011 Structural basis for ubiquitin recognition by a novel domain from human phospholipase A2-activating protein, Fu QS, Zhou CJ, Gao HC, Jiang YJ, Zhou ZR, Hong J, Yao WM, Song AX, Lin DH, Hu HY, 2009

Areas of Focus

Molecular mechanisms of neurodegenerative diseases
Dynamic working principles of protein machines
Application of ultra-large molecular biological NMR technology

Publications

Structural basis for client recognition and activity of Hsp40 chaperones, Jiang Y, Rossi P, Kalodimos CG, 2019
Confirmation for conformational selection, Jiang Y, Kalodimos CG, 2018
Automatic methyl assignment in large proteins by the MAGIC algorithm, Monneau YR, Rossi P, Bhaumik A, Huang C, Jiang Y, Saleh T, Xie T, Xing Q, Kalodimos CG, 2017
NMR Studies of Large Proteins, Jiang Y, Kalodimos CG, 2017
TDP-35 sequesters TDP-43 into cytoplasmic inclusions through binding with RNA, Che MX, Jiang LL, Li HY, Jiang YJ, Hu HY, 2015
Aggregation of polyglutamine-expanded ataxin-3 sequesters its specific interacting partners into inclusions: Implication in a loss-of-function pathology, Yang H, Li JJ, Liu S, Zhao J, Jiang YJ, Song AX, Hu HY, 2014
Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin, Gao YG, Yang H, Zhao J, Jiang YJ, Hu HY, 2014
Structural basis for recognition of the third SH3 domain of Full-length R85(R85FL)/Ponsin by Ataxin-7, Jiang YJ, Zhou CJ, Zhou ZR, Wu M, and Hu HY, 2013
Interaction with Polyglutamine-expanded Huntingtin Alters Cellular Distribution and RNA Processing of Huntingtin Yeast Two-hybrid Protein A (HYPA), Jiang YJ, Che MX, Yuan JQ, Xie YY, Yan XZ, Hu HY, 2011
Aggregation of the 35-kDa fragment of TDP-43 causes formation of cytoplasmic inclusions and alteration of RNA processing, Che MX, Jiang YJ, Xie YY, Jiang LL, Hu HY, 2011
Structural basis for ubiquitin recognition by a novel domain from human phospholipase A2-activating protein, Fu QS, Zhou CJ, Gao HC, Jiang YJ, Zhou ZR, Hong J, Yao WM, Song AX, Lin DH, Hu HY, 2009

Neurodegenerative Diseases Molecular Mechanisms Protein Machines Dynamic Principles Nmr Technology Biological Research Molecular Biology Protein Dynamics Disease Regulation Small Molecule Compounds

Jianhuang Xue - Tongji University

Hua Yang - Tongji University

Chong Wang - Shanghai Normal University

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