2012-present - Chinese Neuroscience Society - Member
Reviewer for journals such as FEBS J, Journal of Neuroinflammation, Neurobiology of Aging
Shanghai Medical Science Award (2008): Second Prize
Chinese Medical Award (2008): Second Prize
Research
Mechanisms of neurodegenerative diseases Mechanisms and interventions of glioma
Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis., Xu Z, Chen S, Li X, Luo G, Li L, Le W., 2006
Proteasome inhibitor lactacystin disturbs the intracellular calcium homeostasis of dopamine neurons in ventral mesencephalic cultures., Li X, Yang D, Li L, Peng C, Chen S, Le W., 2007
Glial cell-derived neurotrophic factor protects against proteasome inhibition-induced dopamine neuron degeneration by suppression of endoplasmic reticulum stress and caspase-3 activation., Li X, Peng C, Li L, Ming M, Yang D, Le W., 2007
Hypoxia increases Abeta generation by altering beta- and gamma-cleavage of APP., Li L, Zhang X, Yang D, Luo G, Chen S, Le W., 2007
Altered macroautophagy in the spinal cord of SOD1 mutant mice., Li L, Zhang X, Le W., 2008
D2/D3 receptor agonist ropinirole protects dopaminergic cell line against rotenone-induced apoptosis through inhibition of caspase- and JNK-dependent pathways., Chen S, Zhang X, Yang D, Du Y, Li L, Li X, Ming M, Le W., 2008
Folic acid protects motor neurons against the increased homocysteine, inflammation and apoptosis in SOD1 G93A transgenic mice., Zhang X, Chen S, Li L, Wang Q, Le W., 2008
Current experimental therapy for Alzheimer's disease., Chen S, Zhang XJ, Li L, Le WD., 2007
Pitx3-transfected astrocytes secrete brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor and protect dopamine neurons in mesencephalon cultures., Yang D, Peng C, Li X, Fan X, Li L, Ming M, Chen S, Le W., 2008
Nurr1 expression and its modulation in microglia., Fan X, Luo G, Ming M, Pu P, Li L, Yang D, Le W., 2009
An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity., Du Y, Yang D, Li L, Luo G, Li T, Fan X, Wang Q, Zhang X, Wang Y, Le W., 2009
Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease., Ming M, Li X, Fan X, Yang D, Li L, Chen S, Gu Q, Le W., 2009
Decreased level of 5-methyltetrahydrofolate: a potential biomarker for pre-symptomatic amyotrophic lateral sclerosis., Zhang X, Chen S, Li L, Wang Q, Le W., 2010
Autophagy dysfunction in Alzheimer's disease., Li L, Zhang X, Le W., 2010
Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis., Zhang X, Li L, Chen S, Yang D, Wang Y, Zhang X, Wang Z, Le W., 2011
Prenatal hypoxia may aggravate the cognitive impairment and Alzheimer's disease neuropathology in APPSwe/PS1A246E transgenic mice., Zhang X, Li L, Zhang X, Xie W, Li L, Yang D, Heng X, Du Y, Doody RS, Le W., 2012
MicroRNA-23a/b and microRNA-27a/b suppress Apaf-1 protein and alleviate hypoxia-induced neuronal apoptosis., Chen Q, Xu J, Li L, Li H, Mao S, Zhang F, Zen K, Zhang CY, Zhang Q., 2014
Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth., Yin Y, Cai X, Chen X, Liang H, Zhang Y, Li J, Wang Z, Chen X, Zhang W, Yokoyama S, Wang C, Li L, Li L, Hou D, Dong L, Xu T, Hiroi T, Yang F, Ji H, Zhang J, Zen K, Zhang CY., 2014
Immune modulatory function of abundant immune-related microRNAs in microvesicles from bovine colostrum., Sun Q, Chen X, Yu J, Zen K, Zhang CY, Li L., 2013
MicroRNA-29a modulates axon branching by targeting doublecortin in primary neurons., Li H, Mao S, Wang H, Zen K, Zhang C, Li L., 2014
miR-17 regulates the proliferation and differentiation of the neural precursor cells during mouse corticogenesis., Mao S, Li H, Sun Q, Zen K, Zhang CY, Li L., 2014
Role of miR-17 family in the negative feedback loop of bone morphogenetic protein signaling in neuron., Sun Q, Mao S, Li H, Zen K, Zhang CY, Li L., 2013
Secreted miR-34a in astrocytic shedding vesicles enhanced the vulnerability of dopaminergic neurons to neurotoxins by targeting Bcl-2., Mao S, Sun Q, Xiao H, Zhang C, Li L., 2015
miR-17-92 facilitates neuronal differentiation of transplanted neural stem/precursor cells under neuroinflammatory conditions., Mao S, Li X, Wang J, Ding X, Zhang C, Li L., 2016
Zika virus infected primary microglia impairs NPCs proliferation and differentiation., Wang J, Liu J, Zhou R, Ding X, Zhang Q, Zhang C, Li L., 2018
Dendritic targeted mRNA expression via a cis-acting RNA UTR element., Lu L, Zhang F, Li Y, Yang A, Guan C, Ding X, Liu Y, Liu Y, Zhang CY, Li L, Zhang Q., 2018
A Simple System for Differentiation of Functional Intestinal Stem Cell-like Cells from Bone Marrow Mesenchymal Stem Cells., Ye L, Sun LX, Wu MH, Wang J, Ding X, Shi H, Lu SL, Wu L, Wei J, Li L, Wang YF., 2018
SIRP alpha deficiency accelerates the pathologic process in models of Parkinson disease., Wang, Jin; Ding, Xin; Wu, Xiangyu; Liu, Jing; Zhou, Rui; Wei, Pingxuan; Zhang, Qipeng; Zhang, Chenyu; Zen, Ke*; Li, Liang*, 2019
Decreased HD-MIR2911 absorption in human subjects with the SIDT1 polymorphism fails to inhibit SARS-CoV-2 replication., Zhen Zhou, Yu Zhou, Xia-Ming Jiang, Yanbo Wang, Xi Chen, Gengfu Xiao, Chen-Yu Zhang, Yongxiang Yi, Lei-Ke Zhang and Liang Li, 2020
Loss of microglial SIRPα promotes synaptic pruning in preclinical models of neurodegeneration., Ding, Xin; Wang, Jin; Huang, Miaoxin; Chen, Zhangpeng; Liu, Jing; Zhang, Qipeng; Zhang, Chenyu; Xiang, Yang; Zen, Ke*; Li, Liang*, 2021
