Professor | Xudong Wu | Asia Growth Partners

Name	Xudong Wu
Contact Information	xudongwu@nju.edu.cn
Language ability	English, Chinese
Province	Jiangsu

Name

Xudong Wu

Contact Information

xudongwu@nju.edu.cn

Language ability

English, Chinese

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Life Sciences
Academic Background & Achievements	2007.1-2009.9 Joint Ph.D. Program: Virginia Commonwealth University, School of Medicine, Department of Microbiology and Immunology 2004.9-2009.7 Ph.D. in Pharmacology: China Pharmaceutical University 1998.9-2003.7 Bachelor's in Pharmacology: China Pharmaceutical University
Work Experience	2018-present - Nanjing University, School of Life Sciences - Professor and Doctoral Supervisor 2012-2018 - Nanjing University, School of Life Sciences - Associate Professor and Master's Supervisor 2009-2011 - Nanjing University, School of Life Sciences - Lecturer
Awards	Jiangsu Province Education and Teaching Research Achievement Award (2018): Second Prize Nanjing City 12th Excellent Academic Paper Award in Natural Science (2018): Second Prize Nanjing City 8th Excellent Academic Paper Award in Natural Science (2009): Second Prize American Society for Biochemistry and Molecular Biology (ASBMB) Travel Award (2008) Nanjing University Xinhua News Agency Teaching Award Fund (2019)

University/Lab Affiliation and Title

Nanjing University

Faculty

Life Sciences

Academic Background & Achievements

2007.1-2009.9 Joint Ph.D. Program: Virginia Commonwealth University, School of Medicine, Department of Microbiology and Immunology
2004.9-2009.7 Ph.D. in Pharmacology: China Pharmaceutical University
1998.9-2003.7 Bachelor's in Pharmacology: China Pharmaceutical University

Work Experience

2018-present - Nanjing University, School of Life Sciences - Professor and Doctoral Supervisor
2012-2018 - Nanjing University, School of Life Sciences - Associate Professor and Master's Supervisor
2009-2011 - Nanjing University, School of Life Sciences - Lecturer

Awards

Jiangsu Province Education and Teaching Research Achievement Award (2018): Second Prize
Nanjing City 12th Excellent Academic Paper Award in Natural Science (2018): Second Prize
Nanjing City 8th Excellent Academic Paper Award in Natural Science (2009): Second Prize
American Society for Biochemistry and Molecular Biology (ASBMB) Travel Award (2008)
Nanjing University Xinhua News Agency Teaching Award Fund (2019)

Areas of Focus	New pathogenesis of inflammatory and metabolic diseases, identification of new therapeutic targets
Publications	CUG-binding protein 1 regulates HSC activation and liver fibrogenesis., Wu Xingxin, Wu Xudong, Ma Yuxiang, Shao Fenli, Tan Yang, Tan Tao, Gu Liyun, Zhou Yang, Sun Beicheng, Sun Yang, Wu Xuefeng, Xu Qiang, 2016 HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells., Wu Xudong, Sun Lixin, Zha Weibin, Studer Elaine, Gurley Emily, Chen Li, Wang Xuan, Hylemon PB, Pandak WM Jr, Sanyal AJ, Zhang Luyong, Wang Guangji, Chen Jie, Wang Jian-Ying, Zhou Huiping, 2010 Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways., Wu Xudong, Zhang Luyong, Gurley Emily, Studer Elaine, Shang Jing, Wang Tao, Wang Cuifen, Yan Ming, Jiang Zhenzhou, Hylemon PB, Sanyal AJ, Pandak WM Jr, Zhou Huiping, 2008 Cis-khellactone inhibited the proinflammatory macrophages via promoting autophagy to ameliorate imiquimod-induced psoriasis., Feng Lili, Song Pingping, Xu Fang, Xu Lisha, Shao Fenli, Guo Mengmeng, Huang Wei, Kong Lingdong, Wu Xudong, Xu Qiang, 2019 Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages., Feng Lili, Sun Yi, Song Pingping, Xu Lisha, Wu Xingxin, Wu Xuefeng, Shen Yan, Sun Yang, Kong Lingdong, Wu Xudong, Xu Qiang, 2019 HIV protease inhibitors in gut barrier dysfunction and liver injury., Wu Xudong, Li Yunzhou, Peng Kesong, Zhou Huiping, 2014 A novel combination of astilbin and low-dose methotrexate respectively targeting A2AAR and its ligand adenosine for the treatment of collagen-induced arthritis., Ma Yuxiang, Gao Zhe, Xu Fang, Liu Li, Luo Qiong, Shen Yan, Wu Xuefeng, Wu Xingxin, Sun Yang, Wu Xudong, Xu Qiang, 2018 Neochromine S5 improves contact hypersensitivity through a selective effect on activated T lymphocytes., Gao Zhe, Ma Yuxiang, Zhao Dan, Zhang Xiong, Zhou Hang, Liu Hailiang, Zhou Yang, Wu Xuefeng, Shen Yang, Sun Yang, Li Jianxin, Wu Xudong, Xu Qiang, 2014 Pentamethoxyflavanone regulates macrophage polarization and ameliorates sepsis in mice., Feng Lili, Song Pingping, Zhou Hang, Li Ang, Ma Yuxiang, Zhang Xiong, Liu Hailiang, Xu Ge, Zhou Yang, Wu Xuefeng, Shen Yan, Sun Yang, Wu Xudong, Xu Qiang, 2014 CPT-11 activates NLRP3 inflammasome through JNK and NF-κB signalings., Li Qian, Zhang Xiong, Wang Weicheng, Li Li, Xu Qiang, Wu Xudong, Gu Yanhong, 2015 The role of CCAAT enhancer-binding protein homologous protein in human immunodeficiency virus protease-inhibitor-induced hepatic lipotoxicity in mice., Wang Yun, Zhang Luyong, Wu Xudong, Gurley EC, Kennedy E, Hylemon PB, Pandak WM, Sanyal AJ, Zhou H, 2013

Areas of Focus

New pathogenesis of inflammatory and metabolic diseases, identification of new therapeutic targets

Publications

CUG-binding protein 1 regulates HSC activation and liver fibrogenesis., Wu Xingxin, Wu Xudong, Ma Yuxiang, Shao Fenli, Tan Yang, Tan Tao, Gu Liyun, Zhou Yang, Sun Beicheng, Sun Yang, Wu Xuefeng, Xu Qiang, 2016
HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells., Wu Xudong, Sun Lixin, Zha Weibin, Studer Elaine, Gurley Emily, Chen Li, Wang Xuan, Hylemon PB, Pandak WM Jr, Sanyal AJ, Zhang Luyong, Wang Guangji, Chen Jie, Wang Jian-Ying, Zhou Huiping, 2010
Prevention of free fatty acid-induced hepatic lipotoxicity by 18beta-glycyrrhetinic acid through lysosomal and mitochondrial pathways., Wu Xudong, Zhang Luyong, Gurley Emily, Studer Elaine, Shang Jing, Wang Tao, Wang Cuifen, Yan Ming, Jiang Zhenzhou, Hylemon PB, Sanyal AJ, Pandak WM Jr, Zhou Huiping, 2008
Cis-khellactone inhibited the proinflammatory macrophages via promoting autophagy to ameliorate imiquimod-induced psoriasis., Feng Lili, Song Pingping, Xu Fang, Xu Lisha, Shao Fenli, Guo Mengmeng, Huang Wei, Kong Lingdong, Wu Xudong, Xu Qiang, 2019
Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages., Feng Lili, Sun Yi, Song Pingping, Xu Lisha, Wu Xingxin, Wu Xuefeng, Shen Yan, Sun Yang, Kong Lingdong, Wu Xudong, Xu Qiang, 2019
HIV protease inhibitors in gut barrier dysfunction and liver injury., Wu Xudong, Li Yunzhou, Peng Kesong, Zhou Huiping, 2014
A novel combination of astilbin and low-dose methotrexate respectively targeting A2AAR and its ligand adenosine for the treatment of collagen-induced arthritis., Ma Yuxiang, Gao Zhe, Xu Fang, Liu Li, Luo Qiong, Shen Yan, Wu Xuefeng, Wu Xingxin, Sun Yang, Wu Xudong, Xu Qiang, 2018
Neochromine S5 improves contact hypersensitivity through a selective effect on activated T lymphocytes., Gao Zhe, Ma Yuxiang, Zhao Dan, Zhang Xiong, Zhou Hang, Liu Hailiang, Zhou Yang, Wu Xuefeng, Shen Yang, Sun Yang, Li Jianxin, Wu Xudong, Xu Qiang, 2014
Pentamethoxyflavanone regulates macrophage polarization and ameliorates sepsis in mice., Feng Lili, Song Pingping, Zhou Hang, Li Ang, Ma Yuxiang, Zhang Xiong, Liu Hailiang, Xu Ge, Zhou Yang, Wu Xuefeng, Shen Yan, Sun Yang, Wu Xudong, Xu Qiang, 2014
CPT-11 activates NLRP3 inflammasome through JNK and NF-κB signalings., Li Qian, Zhang Xiong, Wang Weicheng, Li Li, Xu Qiang, Wu Xudong, Gu Yanhong, 2015
The role of CCAAT enhancer-binding protein homologous protein in human immunodeficiency virus protease-inhibitor-induced hepatic lipotoxicity in mice., Wang Yun, Zhang Luyong, Wu Xudong, Gurley EC, Kennedy E, Hylemon PB, Pandak WM, Sanyal AJ, Zhou H, 2013

Inflammation Metabolic Diseases Pathogenesis Therapeutic Targets Immune Cells Metabolic Syndrome Autoimmune Diseases Macrophages Nafld Triglyceride Metabolism

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