2005.9-2008.7 Doctorate: Sun Yat-sen University, Internal Medicine Endocrinology and Metabolic Diseases
2001.8-2004.7 Master's: Nanjing University Medical School, Internal Medicine Endocrinology and Metabolic Diseases
1992.9-1998.7 Bachelor's: Jilin University, Clinical Medicine
Published 88 SCI papers as first and corresponding author in journals like Cell Metabolism, Diabetes Care, Nature Communications
2023.11-present - Nanjing University Medical School Affiliated Drum Tower Hospital Clinical Medical Research Institute - Director
2022.12-present - Nanjing University Medical School Affiliated Drum Tower Hospital - Vice President
2022.11-present - Nanjing University Metabolic Disease Research Institute - Director
2022.3-2023.5 - Nanjing University Medical School Affiliated Drum Tower Hospital Endocrinology Department - Administrative Director
2021.2-present - Nanjing University Medical School Affiliated Drum Tower Hospital Science and Technology Department - Director
2016.7-present - Nanjing Medical University - Doctoral Supervisor
2015.6-present - Nanjing University - Doctoral Supervisor
2015.3-2022.2 - Nanjing University Medical School Affiliated Drum Tower Hospital Endocrinology Department - Administrative Deputy Director
2016.12-present - Nanjing University Medical School Affiliated Drum Tower Hospital - Chief Physician
2012.4-2016.4 - Nanjing University Clinical Medicine Postdoctoral Mobile Station - Postdoctoral
2010.10-2016.11 - Nanjing University Medical School Affiliated Drum Tower Hospital - Associate Chief Physician
2009.9-2010.9 - University of Sheffield, UK - Visiting Scholar
2005.1-2010.9 - Nanjing University Medical School Affiliated Drum Tower Hospital - Attending Physician
1998.8-2004.12 - Nanjing University Medical School Affiliated Drum Tower Hospital - Resident Physician
China's Top Ten Most Influential Diabetes Research Award
Jiangsu Medical Science and Technology Award First Prize
Jiangsu Province Medical New Technology Introduction First Prize
Research
Diabetes Obesity Fatty Liver
Extracellular vesicles mediate the communication of adipose tissue with brain and promote cognitive impairment associated with insulin resistance., Jin Wang, Liang Li, Zhou Zhang, Xuhong Zhang, Ye Zhu, Chenyu Zhang, Yan Bi, 2022
Enhancement of Impaired Olfactory Neural Activation and Cognitive Capacity by Liraglutide, but not Dapagliflozin or Acarbose, in Patients With Type 2 Diabetes: A 16-Week Randomized Parallel Comparative Study., Haiyan Cheng, Zhou Zhang, Bing Zhang, Wen Zhang, Jin Wang, Wenyu Ni, Yingwen Miao, Jiani Liu, Yan Bi, 2022
Harvesting stem cell exosomes from herringbone microfluidic bioreactor for wound healing., Junjie Huang, Hanxu Chen, Ning Li, Luoran Shang, Yan Bi, Yuanjin Zhao, 2023
Multiple Bio-Actives Loaded Gellan Gum Microfibers from Microfluidics for Wound Healing., Jiahui Guo, Yunru Yu, Yingbo Shen, Xiaoyan Sun, Yan Bi, Yuanjin Zhao, 2023
Gender differences in the association of body composition and biopsy-proved nonalcoholic steatohepatitis., Da Fang, Wenjuan Tang, Xiaoyu Zhao, Haixiang Sun, Tianwei Gu, Yan Bi, 2022
The association between visceral adipocyte hypertrophy and NAFLD in subjects with different degrees of adiposity., Haixiang Sun, Da Fang, Hongdong Wang, Jin Wang, Yue Yuan, Shanshan Huang, Huayang Ma, Tianwei Gu, Yan Bi, 2023
Altered brain spontaneous and synchronization activity in latent autoimmune diabetes in adults: A resting-state functional MRI study., Yingwen Miao, Jin Wang, Bing Zhang, Wen Zhang, Xiang Xu, Yingjiao Hou, Qun Ding, Congcong Yu, Zhou Zhang, Yan Bi, Dalong Zhu, 2023
Low levels of osteocalcin, but not CTX or P1NP, are associated with nonalcoholic hepatic steatosis and steatohepatitis., Da Fang, Hongli Yin, Xinlu Ji, Haixiang Sun, Xiaoyu Zhao, Yan Bi, Tianwei Gu, 2023
Comparison on cognitive outcomes of antidiabetic agents for type 2 diabetes: A systematic review and network meta-analysis., Sai Tian, Jiaxuan Jiang, Jin Wang, Zhou Zhang, Yingwen Miao, Xinlu Ji, Yan Bi, 2023
Th1 bias of liver mucosal-associated invariant T cells promotes hepatic gluconeogenesis in type 2 diabetes mellitus., Wenjuan Tang, Kang Ge, Lei Shen, Hongdong Wang, Wenhuan Feng, Xitai Sun, Xuehui Chu, Dalong Zhu, Hongli Yin, Yan Bi, 2023
The role of miRNAs carried by extracellular vesicles in type 2 diabetes and its complications., Yining Chao, Tianwei Gu, Zhou Zhang, Tianyu Wu, Jin Wang, Yan Bi, 2023
The presence and severity of NAFLD are associated with cognitive impairment and hippocampal damage., Yingwen Miao, Bing Zhang, Xitai Sun, Xuelin Ma, Da Fang, Wen Zhang, Tianyu Wu, Xiang Xu, Congcong Yu, Yinjiao Hou, Qun Ding, Sijue Yang, Linqing Fu, Zhou Zhang, Yan Bi, 2023
Increased plasmablasts enhance T cell-mediated beta cell destruction and promote the development of type 1 diabetes., Qing Ling, Lei Shen, Wei Zhang, DuoDuo Qu, Hongdong Wang, Bin Wang, Yong Liu, Jing Lu, Dalong Zhu, Yan Bi, 2022
Expression and clinical significance of VISTA and PD-L1 in adrenocortical carcinoma., Ziwei Zhang, Menglian Li, Jianjun Wang, Mengsi Liu, Huan Chen, Yuan Lou, Yijie Wang, Qi Sun, Dalong Zhu, Ping Li, Yan Bi, 2022
The correlation of the neutrophil-lymphocyte ratio to clinical and imaging parameters in patients with thyroid eye disease., Xiaowen Zhang, Chen Han, Hongwei Wang, Xinghong Sun, Xin Dou, Xueying He, Di Wu, Shanmei Shen, Dalong Zhu, Xinlin Zhang, Yan Bi, 2022
Associations Between Obesity and Kidney Disease in Chinese Men and Women With Type 2 Diabetes: A Retrospective Cohort Study., Yangyang Xia, Chunming Jiang, Jing Lu, Jie Liu, Tianwei Gu, Yan Bi, 2022
Association of Omental Adipocyte Hypertrophy and Fibrosis with Human Obesity and Type 2 Diabetes., Fangcen Liu, Jielei He, Boxun Liu, Pengzi Zhang, Hongdong Wang, Xitai Sun, Xuehui Chu, Wenxian Guan, Wenhuan Feng, Yan Bi, Dalong Zhu, 2021
Risk Prediction Model of Gestational Diabetes Mellitus in a Chinese Population Based on a Risk Scoring System., Yanmei Wang, Zhijuan Ge, Lei Chen, Jun Hu, Wenting Zhou, Shanmei Shen, Dalong Zhu, Yan Bi, 2021
Are Chinese Patients with Type 2 Diabetes and a Body Mass Index of 27.5-32.5 kg/m2 Suitable for Metabolic Surgery? A One-Year Post-Surgery Study., Ning-Jing Zhang, Yu-Zhe Fu, Xiao-Dong Shan, Ning Zhang, Xi-Tai Sun, Xue-Hui Chu, Yan Bi, Da-Long Zhu, Wen-Huan Feng, 2021
One repeated transplantation of allogeneic umbilical cord mesenchymal stromal cells in type 1 diabetes: an open parallel controlled clinical study., Jing Lu, Shan-Mei Shen, Qing Ling, Bin Wang, Li-Rong Li, Wei Zhang, Duo-Duo Qu, Yan Bi, Da-Long Zhu, 2021
Corneal confocal microscopy: A useful tool for diagnosis of small fiber neuropathy in type 2 diabetes., Yu Jin, Weimin Wang, Wei Chen, Simin Guo, Chenxi Li, Dalong Zhu, Yan Bi, 2021
Body Adiposity Index Is Predictive of Weight Loss after Roux-en-Y Gastric Bypass., Fangcen Liu, Jielei He, Ye Zhu, Hongdong Wang, Wenhuan Feng, Xitai Sun, Yan Bi, Dalong Zhu, 2021
Peripheral Administration of NMU Promotes White Adipose Tissue Beiging and Improves Glucose Tolerance., Yue Yuan, Hongdong Wang, Jielei He, Haixiang Sun, Dalong Zhu, Yan Bi, 2021
Better Islet Function and Cardiovascular Autonomic Function in Chinese Type 2 Diabetic Patients with Pure Small Fiber Neuropathy than with Mixed Neuropathy., Chenxi Li, Weimin Wang, Wenyu Ni, Yu Jin, Simin Guo, Jiewen Jin, Chuhui Chen, Wei Chen, Yan Bi, Dalong Zhu, 2021
Connecting Peripheral to Central Neuropathy: Examination of Nerve Conduction Combined with Olfactory Tests in Patients with Type 2 Diabetes., Wenyu Ni, Zhou Zhang, Bing Zhang, Wen Zhang, Haiyan Cheng, Yingwen Miao, Wei Chen, Jiani Liu, Dalong Zhu, Yan Bi, 2021
Modulation of gut microbiota contributes to effects of intensive insulin therapy on intestinal morphological alteration in high fat-diet treated mice., Wang HD, Tang WJ, Zhang PZ, Zhang Z, He J, Zhu DL, Bi Y, 2020
Influence of Fetal Sex on Perinatal Outcomes in Women With Gestational Diabetes Mellitus., Jun Hu, Zhijuan Ge, Qianyue Xu, Shanmei Shen, Yanmei Wang, Dalong Zhu, Yan Bi, 2020
Oxygen Therapy Alleviates Hepatic Steatosis by Inhibiting Hypoxia-Inducible factor-2α., Lei Yu, Haoran Wang, Xiaoxue Han, Honghui Liu, Dalong Zhu, Wenhuan Feng, Jinhui Wu, Yan Bi, 2020
Adipose Morphology: a Critical Factor in Regulation of Human Metabolic Diseases and Adipose Tissue Dysfunction., Fangcen Liu, Jielei He, Hongdong Wang, Dalong Zhu, Yan Bi, 2020
Nocturnal ventricular arrhythmias are associated with the severity of cardiovascular autonomic neuropathy in type 2 diabetes., Chen C, Wang W, Zhou W, Jin J, Chen W, Zhu D, Bi Y, 2019
Low serum bilirubin levels contribute to the presence and progression of distal symmetrical polyneuropathy in Chinese patients with type 2 diabetes., Jin J, Wang W, Gu T, Chen C, Sun J, Chen W, Bi Y, Zhu D, 2019
Metabolic effects and safety of Roux-en-Y gastric bypass surgery vs. conventional medication in obese Chinese patients with type 2 diabetes., Feng W, Yin T, Chu X, Shan X, Jiang C, Wang Y, Qian Y, Zhu D, Sun X, Bi Y, 2019
Olfactory Dysfunction Mediates Adiposity in Cognitive Impairment of Type 2 Diabetes: Insights From Clinical and Functional Neuroimaging Studies., Zhang Z, Zhang B, Wang X, Zhang X, Yang QX, Qing Z, Zhang W, Zhu D, Bi Y, 2019
Adipose group 1 innate lymphoid cells promote adipose tissue fibrosis and diabetes in obesity., Wang H, Shen L, Sun X, Liu F, Feng W, Jiang C, Chu X, Ye X, Jiang C, Wang Y, Zhang P, Zang M, Zhu D, Bi Y, 2019
Comparative effect of saxagliptin and glimepiride with a composite endpoint of adequate glycaemic control without hypoglycaemia and without weight gain in patients uncontrolled with metformin therapy: Results from the SPECIFY study, a 48-week, multi-centre, randomized, controlled trial., Gu T, Ma J, Zhang Q, Zhu L, Zhang H, Xu L, Cheng J, Shi B, Li D, Shao J, Sun Z, Zhong S, Bi Y, Zhu D, 2019
Improved skeletal muscle energy metabolism relates to the recovery of β cell function by intensive insulin therapy in drug naïve type 2 diabetes., Tang W, Zhang B, Wang H, Li M, Wang H, Liu F, Zhu D, Bi Y, 2019
The Association of gestational weight gain and adverse pregnancy outcomes in women with gestational diabetes mellitus., Xu Q, Ge Z, Hu J, Shen S, Bi Y, Zhu D, 2019
Increased circulating conjugated primary bile acids are associated with hyperandrogenism in women with polycystic ovary syndrome., Zhang B, Shen S, Gu T, Hong T, Liu J, Sun J, Wang H, Bi Y, Zhu D, 2019
Erythropoietin suppresses hepatic steatosis and obesity by inhibiting endoplasmic reticulum stress and upregulating fibroblast growth factor 21., Hong T, Ge Z, Zhang B, Meng R, Zhu D, Bi Y, 2019
Type 1 innate lymphoid cells are associated with type 2 diabetes., Liu F, Wang H, Feng W, Ye X, Sun X, Jiang C, Chu X, Zhang P, Jiang C, Wang Y, Zhu D, Bi Y, 2019
Active Surveillance of Low-risk Papillary Thyroid Carcinoma: A Promising Strategy Requiring Additional Evidence., Yuyang Ze, Xiaowen Zhang, Fei Shao, Lin Zhu, Shanmei Shen, Dalong Zhu, Yan Bi, 2019
Risk of beta-cell antoimmunity presence of progression to type 1 diabetes: a systemic review and meta-analysis., Ling Q, Lu J, Li J, Xu Q, Zhu D, Bi Y, 2018
Association of Androgen Excess with Glucose Intolerance in Women with Polycystic Ovary Syndrome., Zhang B, Wang J, Shen S, Liu J, Sun J, Gu T, Ye X, Zhu D, Bi Y, 2018
Prolactin improves hepatic steatosis via CD36 pathway., Zhang P, Ge Z, Wang H, Feng W, Sun X, Chu X, Jiang C, Wang Y, Zhu D, Bi Y, 2018
Altered Odor-Induced Brain Activity as an Early Manifestation of Cognitive Decline in Patients with Type 2 Diabetes., Zhang Z, Zhang B, Wang X, Zhang X, Yang QX, Qing Z, Lu J, Bi Y, Zhu D, 2018
Erythropoietin alleviates hepatic steatosis by activating SIRT1-mediated autophagy., Hong T, Ge Z, Meng R, Wang H, Zhang P, Tang S, Lu J, Gu T, Zhu D, Bi Y, 2018
A retrospective study on association between obesity and cardiovascular risk diseases with aging in Chinese adults., Sun J, Zhou W, Gu T, Zhu D, Bi Y, 2018
Cardiovascular and microvascular outcomes of glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized controlled cardiovascular outcome trials with trial sequential analysis., Zhang X, Shao F, Zhu L, Ze Y, Zhu D, Bi Y, 2018
Suppression of Rho-kinase 1 is responsible for insulin regulation of the AMPK/SREBP-1c pathway in skeletal muscle cells exposed to palmitate., Tang S, Wu W, Tang W, Ge Z, Wang H, Hong T, Zhu D, Bi Y, 2017
Modulation of gut microbiota contributes to curcumin-mediated attenuation of hepatic steatosis in rats., Feng W, Wang H, Zhang P, Gao C, Tao J, Ge Z, Zhu D, Bi Y, 2017
Global Epidemiology of Diabetic Foot Ulceration: A Systematic Review and Meta-Analysis., Zhang P, Lu J, Jing Y, Tang S, Zhu D, Bi Y, 2017
Insulin restores UCP3 activity and decreases energy surfeit to alleviate lipotoxicity in skeletal muscle., Tang W, Tang S, Wang H, Ge Z, Zhu D, Bi Y, 2017
Comparative efficacy of anti-diabetic agents on nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized and non-randomized studies., Tang W, Xu Q, Hong T, Tong G, Feng W, Shen S, Bi Y, Zhu D, 2016
Erythropoietin alleviates hepatic insulin resistance via PPARγ-dependent AKT activation., Ge Z, Zhang P, Hong T, Meng R, Bi Y, Zhu D, 2015
Comparison of the effects on glycaemic control and β-cell function in newly diagnosed type 2 diabetes patients treated with exenatide, insulin or pioglitazone: a multicentre randomized parallel-group trial (the CONFIDENCE study)., Xu W, Bi Y, Sun Z, Li J, Guo L, Yang T, Wu G, Shi L, Feng Z, Qin L, Guo X, Luo Z, Lu J, Shan Z, Yang W, Ji Q, Yan L, Li H, Yu X, Li S, Zhou Z, Lv X, Liang Z, Lin S, Zeng L, Yan J, Ji L, Weng J, 2015
Metformin attenuates palmitic acid-induced insulin resistance in L6 cells through the AMP-activated protein kinase/sterol regulatory element-binding protein-1c pathway., Wu W, Tang S, Shi J, Yin W, Cao S, Bu R, Zhu D, Bi Y, 2015
Elevated Plasma level of Pigment Epithelium-Derived Factor in type 2 diabetic patients is reduced by metformin treatment in association with weight loss., Ge Z, Zhang P, Bi Y, Li C, Yang H, Zhu D, 2015
Role for sterol regulatory element binding protein-1c activation in mediating skeletal muscle insulin resistance via repression of rat insulin receptor substrate-1 transcription., Bi Y, Wu W, Shi J, Liang H, Yin W, Chen Y, Tang S, Cao S, Cai M, Shen S, Gao Q, Weng J, Zhu D, 2014
Effects of exenatide, insulin, and pioglitazone on liver fat content and body fat distributions in drug-naive subjects with type 2 diabetes., Bi Y, Zhang B, Xu W, Yang H, Feng W, Li M, Tong G, Shen S, Wang X, Zhu B, Weng J, Zhu D, 2014
Correlations between A1c, fasting glucose, 2h postload glucose, and β-cell function in the Chinese populations., Li C, Yang H, Tong G, Shen S, Hu Y, Feng W, Bi Y, Zhu D, 2014
The effect of metformin on β-cell function in non-obese Chinese subjects with newly diagnosed type 2 diabetes., Bi Y, Tong G, Yang H, Cai M, Ma J, Liang J, Xin B, Miao H, Peng Z, Zhu D, 2013
Prevalence of hypoglycemia by intensive bedside glucose monitoring among hospitalized patients with diabetes mellitus in China., Bi Y, Yan J, Tang W, Yang J, Weng J, 2013
Association of β-cell function and insulin sensitivity with fasting and 2h plasma glucose in a large Chinese population., Bi Y, Zeng L, Zhu D, Yan J, Zhang Y, Tong G, Mu P, Shen S, Hu Y, Yu Q, Liang H, Weng J, 2012
Decreased beta cell function and insulin sensitivity contributed to increasing fasting glucose in Chinese., Bi Y, Zhu D, Jing Y, Hu Y, Feng W, Shen S, Tong G, Shen X, Yu T, Song D, Yang D, 2012
Comparative efficacy and safety of long-acting insulin analogs in patients with type 2 diabetes failing on oral therapy: systemic review and meta-analyses., Bi Y, Li X, Yang D, Hao Y, Liang H, Zhu D, Weng J, 2012
SLC30A8 polymorphism and type 2 diabetes risk: Evidence from 27 study groups., Jing Y, Sun Q, Bi Y, Shen S, Zhu D, 2011
Inhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic rats., Sun W, Bi Y, Liang H, Cai M, Chen X, Zhu Y, Li M, Xu F, Yu Q, He X, Ye J, Weng J, 2011
The status of glycemic control: a cross-sectional survey in outpatients with type 2 diabetes mellitus across tertiary, secondary and primary hospitals in Jiangsu Province of China., Bi Y, Zhu D, Cheng J, Zhu Y, Xu N, Cui S, Li W, Cheng X, Wang F, Hu Y, Shen S, Weng J, 2010
Increased CPT-1 expression and decreased SREBP-1c expression is associated with reduced intramuscular triglyceride accumulation after insulin therapy in high fat diet and streptozotocin induced diabetic rats., Bi Y, Cai M, Liang H, Sun W, Li X, Wang C, Zhu Y, Chen X, Li M, Weng J, 2009
A single nucleotide polymorphism (SNP) rs2072907 in the adiponutrin gene (ADPN) was not associated with obesity and type 2 diabetes in Chinese Population., Liang H, Cai M, Bi Y, Zhu Y, Yan J, Weng J, 2009
Effects of early insulin therapy on nuclear factor kB and cytokine gene expressions in the liver and muscle of fat-fed, streptozocin-treated diabetic SD rats., Bi Y, Sun W, Chen X, Li M, Liang H, Cai M, Zhu Y, He X, Xu F, Weng J, 2008
Inadequate glycaemic control and antidiabetic therapy among inpatients with type 2 diabetes in Guangdong Province of China., Bi Y, Yan J, Liao Z, Li Y, Tang K, Xue Y, Yang H, Li L, Cai D, Wu G, Zhang F, Lin S, Xiao Z, Zhu D, Weng J, 2008
