1988.9-1992.7 Bachelor's Degree: Peking University, Department of Biology
1992.8-1995.7 Master's Degree: Chinese Academy of Medical Sciences, Institute of Basic Medical Sciences
1995.8-2000.12 PhD: University of Texas Southwestern Medical Center
2001.1-2002.12 Postdoctoral Researcher: University of Texas Southwestern Medical Center
2003.1-2009.8 Postdoctoral Researcher: Massachusetts Institute of Technology, Department of Biology
2009.8-present Professor: Central South University, School of Life Sciences
The Charles A. King Medical Foundation Fellowship, 2004-2005
Ministry of Education New Century Excellent Talents, 2010
Research
Genetics Molecular Biology Neurobiology Molecular genetic mechanisms and animal model studies of human diseases
Neuronal NT-3 is not required for synaptic transmission or long-term potentiation in area CA1 of the adult mouse hippocampus, Ma L., Reis G., Parada LF., Schuman EM., 1999
Molecular characterization of the TrkA/NGF receptor minimal enhancer reveals regulation by multiple cis elements to drive embryonic neuron expression, Ma L., Merenmies J., Parada LF., 2000
mKLF7, a potential transcriptional regulator of TrkA nerve growth factor receptor expression in sensory and sympathetic neurons, Lei L., Ma L., Nef S., Thai T., Parada LF., 2001
Neurotrophin-3 is required for appropriate establishment of thalamocortical connections, Ma L., Harada T., Harada C., Romero MI., Hebert JM., McConnell, SK., Parada, LF., 2002
Brn3a regulation of TrkA/NGF receptor expression in developing sensory neurons, Ma L., Lei L., Raisa Eng S., Turner E., Parada LF., 2003
TrkB signaling regulates the developmental maturation of the somatosensory cortex, Lush M., Ma L. Parada LF., 2005
Mutations in the Caenorhabditis elegans U2AF large subunit UAF-1 alter the choice of a 3′ splice site in vivo, Ma L., Horvitz HR., 2009
Caenorhabditis elegans operons contain a higher proportion of genes with multiple transcripts and use 3′ splice sites differentially, Wang F., Huang S., Ma L., 2010
In vivo effects on intron retention and exon skipping by the U2AF large subunit and SF1/BBP in the nematode Caenorhabditis elegans, Ma L., Tan Z., Teng Y., Hoersch S., Horvitz HR., 2011
Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy, Lu J, Tan J, Durairajan S, Liu L, Zhang Z, Ma L, Shen H, Chan H, Li M., 2012
The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing, Ma L., Gao X., Luo J., Huang L., Teng Y., Horvitz HR., 2012
The Caenorhabditis elegans iodotyrosine deiodinase ortholog SUP-18 functions through a conserved channel SC-box to regulate the muscle two-pore domain potassium channel SUP-9, de la Cruz IP., Ma L., Horvitz HR., 2014
Scoring the collective effects of SNPs: associations of minor alleles with complex traits in model organisms, Yuan, D., Zhu, Z., Tan, X., Liang, J., Zeng, C., Zhang, J., Chen, J., Ma, L., Dogan, A., Brockmann, G., Medina, E., Rice, A.D., Moyer, R.W., Man, X., Yi, K., Li, Y., Lu, Q., Huang, Y., and Huang, S., 2014
Molecular mechanisms and animal models of spinal muscular atrophy, Edens BM., Ajroud-Driss S., Ma L., Ma Y., 2014
The survival motor neuron gene smn-1 interacts with the U2AF large subunit gene uaf-1 to regulate Caenorhabditis elegans lifespan and motor functions, Gao X., Teng Y., Luo J., Huang L., Li M., Zhang Z., Ma Y., Ma L., 2014
The BLI-3/TSP-15/DOXA-1 dual oxidase complex is required for iodide toxicity in C. elegans, Xu Z., Luo J., Li Y., Ma L., 2015
Neuropeptide receptors NPR-1 and NPR-2 regulate C. elegans avoidance response to the plant stress hormone methyl salicylate, Luo J., Xu Z., Tan Z., Zhang Z., Ma L., 2015
Non-aggregating tau phosphorylation by Cdk5 contributes to motor neuron degeneration in spinal muscular atrophy, Miller N., Feng Z., Edens B., Yang B., Shi H., Sze C., Hong B., Su S., Cantu J., Topczewski J., Crawford T., Ko CP., Sumner C., Ma L., Ma Y., 2015
Altered expression of EPO might underlie hepatic hemangiomas in LRRK2 knockout mice, Wu B., Xiao K., Zhang Z., Ma L., 2016
Contra-directional coupling of Nur77 and Nurr1 in neurodegeneration: A novel mechanism for memantine-induced anti-inflammation and anti-mitochondrial Impairment, Wei X., Gao H., Zou J., Liu X., Chen D., Liao J., Xu Y., Ma L., Tang B., Zhang Z., Cai X., Jin K., Xia Y., Wang Q., 2016
Identification of ANKDD1B variants in an ankylosing spondylitis pedigree and a sporadic patient, Tan Z.*, Zeng H., Xu Z., Tian Q., Gao X., Zhou C., Zheng Y., Wang J., Ling G., Wang B., Yang Y., Ma L., 2018
