Professor | Shuyu Zhang | Asia Growth Partners

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Name	Shuyu Zhang
Contact Information	zhangshuyu@scu.edu.cn
Language ability	Chinese, English
Province	Sichuan

Upload Avatar (500 x 500)

Name

Shuyu Zhang

Contact Information

zhangshuyu@scu.edu.cn

Language ability

Chinese, English

Province

Sichuan

University/Lab Affiliation and Title	Sichuan University
Faculty	West China Institute of Basic Medicine and Forensic Medicine
Work Experience	2010-2018 - Suzhou University, School of Radiation Medicine and Protection - Faculty 2019-present - Sichuan University - Established Radiation Medicine Research Laboratory
Awards	2015: National Natural Science Foundation of China Excellent Young Scientist Fund Sichuan Province Second Prize Ministry of Education Second Prize Chinese Society for Radiation Protection Second Prize China Nuclear Energy Industry Association Second Prize Sichuan Province Teaching Achievement First Prize Chinese Society of Toxicology Outstanding Young Scientist Award

University/Lab Affiliation and Title

Sichuan University

Faculty

West China Institute of Basic Medicine and Forensic Medicine

Work Experience

2010-2018 - Suzhou University, School of Radiation Medicine and Protection - Faculty
2019-present - Sichuan University - Established Radiation Medicine Research Laboratory

Awards

2015: National Natural Science Foundation of China Excellent Young Scientist Fund
Sichuan Province Second Prize
Ministry of Education Second Prize
Chinese Society for Radiation Protection Second Prize
China Nuclear Energy Industry Association Second Prize
Sichuan Province Teaching Achievement First Prize
Chinese Society of Toxicology Outstanding Young Scientist Award

Areas of Focus	Tumor radiosensitivity mechanisms Nuclear radiation injury prevention strategies
Publications	Chaperone- and PTM-mediated activation of IRF1 tames radiation-induced cell death and inflammation response., Geng F, Chen J, Yang T, Tang Z, Song B, Yan T, Liu Y, Sun C, Tan L, Yu D, Cao J, Zhang S., 2024 Single-cell RNA-Seq analysis of molecular changes during radiation-induced skin injury: the radioprotective role of Nur77., Tao Yan, Ping Yang, Hao Bai, Bin Song, Yulan Liu, Jiajia Wang, Yuehua Zhang, Tu W, Yu D, Zhang S., 2024 UV radiation-induced peptides in frog skin confer protection against cutaneous photodamage through suppressing MAPK signaling., Yang T, Geng F, Tang X, Yu Z, Liu Y, Song B, Tang Z, Wang B, Ye B, Yu D, Zhang S., 2024 Tetrahydrobiopterin metabolism attenuates ROS generation and radiosensitivity through LDHA S-nitrosylation: novel insight into radiogenic lung injury., Feng Y#, Feng Y, Gu L, Mo W, Wang X, Song B, Hong M, Geng F, Huang P, Zhu W, Jiao Y, Zhang Q, Ding WQ, Cao J, Zhang S., 2024 A frog skin-derived peptide targeting SCD1 exerts radioprotective effects against skin injury by inhibiting STING-mediated inflammation., Geng F#, Zhong L#, Yang T#, Chen J, Yang P, Jiang F, Yan T, Song B, Yu Z, Yu D. Zhang J, Cao J, Zhang S., 2024 Current insights and future perspectives of ultraviolet radiation (UV) exposure: Friends and foes to the skin and beyond the skin., Tang X, Yang T, Yu D, Xiong H, Zhang S., 2024 Cell fate regulation governed by p53: Friends or reversible foes in cancer therapy., Song B, Yang P, Zhang S., 2024 Tissue fibrosis induced by radiotherapy: current understanding of the molecular mechanisms, diagnosis and therapeutic advances., Yu Z, Xu C, Song B, Zhang S, Chen C, Li C, Zhang S., 2023 PPARα activation by fenofibrate ameliorates radiation‐induced skin injury., Liu P, Yu D, Sheng W, Geng F, Zhang J, Zhang S., 2022 Interferon regulatory factor 1-triggered free ubiquitin protects the intestines against radiation-induced injury via CXCR4/FGF2 signaling., Jiao Y, Xu J, Song B, Wu A, Pan L, Xu Y, Geng F, Li X, Zhao C, Hong M, Meng X, Luo J, Liu P, Li M, Zhu W, Cao J, Zhang S., 2022 Additional Evidence for Commonalities between COVID-19 and Radiation Injury: Novel Insight into COVID-19 Candidate Drugs., Geng F, Chen J, Tang S, Azzam EI, Zhang J, Zhang S., 2022 Genome-wide analysis reveals zinc transporter ZIP9 regulated by DNA methylation promotes radiation-induced skin fibrosis via the TGF-β signaling pathway., Qiu Y, Gao Y, Yu D, Zhong L, Cai W, Ji J, Geng F, Tang G, Zhang H, Cao J, Zhang J, Zhang S., 2020 Activation of PPARα by clofibrate sensitizes pancreatic cancer cells to radiation through the Wnt/β-catenin pathway., Xue J, Zhu W, Song J, Jiao Y, Luo J, Yu C, Zhou J, Wu J, Chen M, Ding WQ, Cao J, Zhang S., 2018 The Nrf2/GCH1/BH4 axis ameliorates radiation-induced skin injury by modulating the ROS cascade., Xue J, Yu C, Sheng W, Zhu W, Luo J, Zhang Q, Yang H, Cao H, Wang W, Zhou J, Wu J, Cao P, Chen M, Ding WQ, Cao J, Zhang S., 2017 Proteomic profiling of radiation-induced skin fibrosis in rats: targeting the ubiquitin-proteasome system., Wang W, Luo J, Sheng W, Xue J, Li M, Ji J, Liu P, Zhang X, Cao J, Zhang S., 2016

Areas of Focus

Tumor radiosensitivity mechanisms
Nuclear radiation injury prevention strategies

Publications

Chaperone- and PTM-mediated activation of IRF1 tames radiation-induced cell death and inflammation response., Geng F, Chen J, Yang T, Tang Z, Song B, Yan T, Liu Y, Sun C, Tan L, Yu D, Cao J, Zhang S*., 2024
Single-cell RNA-Seq analysis of molecular changes during radiation-induced skin injury: the radioprotective role of Nur77., Tao Yan, Ping Yang, Hao Bai, Bin Song, Yulan Liu, Jiajia Wang, Yuehua Zhang, Tu W*, Yu D*, Zhang S*., 2024
UV radiation-induced peptides in frog skin confer protection against cutaneous photodamage through suppressing MAPK signaling., Yang T, Geng F, Tang X, Yu Z, Liu Y, Song B, Tang Z, Wang B, Ye B, Yu D, Zhang S*., 2024
Tetrahydrobiopterin metabolism attenuates ROS generation and radiosensitivity through LDHA S-nitrosylation: novel insight into radiogenic lung injury., Feng Y#, Feng Y, Gu L, Mo W, Wang X, Song B, Hong M, Geng F, Huang P, Zhu W, Jiao Y, Zhang Q, Ding WQ, Cao J*, Zhang S*., 2024
A frog skin-derived peptide targeting SCD1 exerts radioprotective effects against skin injury by inhibiting STING-mediated inflammation., Geng F#, Zhong L#, Yang T#, Chen J, Yang P, Jiang F, Yan T, Song B, Yu Z, Yu D. Zhang J*, Cao J*, Zhang S*., 2024
Current insights and future perspectives of ultraviolet radiation (UV) exposure: Friends and foes to the skin and beyond the skin., Tang X, Yang T, Yu D, Xiong H*, Zhang S*., 2024
Cell fate regulation governed by p53: Friends or reversible foes in cancer therapy., Song B, Yang P, Zhang S*., 2024
Tissue fibrosis induced by radiotherapy: current understanding of the molecular mechanisms, diagnosis and therapeutic advances., Yu Z, Xu C, Song B, Zhang S, Chen C, Li C*, Zhang S*., 2023
PPARα activation by fenofibrate ameliorates radiation‐induced skin injury., Liu P, Yu D, Sheng W, Geng F, Zhang J*, Zhang S*., 2022
Interferon regulatory factor 1-triggered free ubiquitin protects the intestines against radiation-induced injury via CXCR4/FGF2 signaling., Jiao Y, Xu J, Song B, Wu A, Pan L, Xu Y, Geng F, Li X, Zhao C, Hong M, Meng X, Luo J, Liu P, Li M, Zhu W, Cao J*, Zhang S*., 2022
Additional Evidence for Commonalities between COVID-19 and Radiation Injury: Novel Insight into COVID-19 Candidate Drugs., Geng F, Chen J, Tang S, Azzam EI, Zhang J*, Zhang S*., 2022
Genome-wide analysis reveals zinc transporter ZIP9 regulated by DNA methylation promotes radiation-induced skin fibrosis via the TGF-β signaling pathway., Qiu Y, Gao Y, Yu D, Zhong L, Cai W, Ji J, Geng F, Tang G, Zhang H, Cao J, Zhang J*, Zhang S*., 2020
Activation of PPARα by clofibrate sensitizes pancreatic cancer cells to radiation through the Wnt/β-catenin pathway., Xue J, Zhu W, Song J, Jiao Y, Luo J, Yu C, Zhou J, Wu J, Chen M, Ding WQ, Cao J*, Zhang S*., 2018
The Nrf2/GCH1/BH4 axis ameliorates radiation-induced skin injury by modulating the ROS cascade., Xue J, Yu C, Sheng W, Zhu W, Luo J, Zhang Q, Yang H, Cao H, Wang W, Zhou J, Wu J, Cao P, Chen M, Ding WQ, Cao J*, Zhang S*., 2017
Proteomic profiling of radiation-induced skin fibrosis in rats: targeting the ubiquitin-proteasome system., Wang W, Luo J, Sheng W, Xue J, Li M, Ji J, Liu P, Zhang X, Cao J, Zhang S*., 2016

Radiation Tumor Sensitivity Mechanism Nuclear Injury Prevention Strategy Research Oncology

Zhenhua Deng - Sichuan University

Changlong Li - Sichuan University

Ji Liu - Sichuan University

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