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Liu Hao
Basic Medicine and Forensic Medicine
Sichuan University
Sichuan
Language: English, Chinese
Metabolism
Tumor
Cancer
Development
Mechanism
Research
Oncology
Biochemistry
Molecular Biology
Cellular Processes
Areas of Focus
- Role and mechanism of metabolism in tumor occurrence and development
Work Experience
- 2002-present - Sichuan University - Faculty member
- 2008-2011 - University of South Alabama Mitchell Cancer Institute - Postdoctoral research
Academic Background & Achievements
- 2002 - PhD in Biochemistry and Molecular Biology: Sichuan University Huaxi Medical Center
- Completed a Youth Science Fund project and a National Natural Science Foundation Youth Fund project as project leader
- Published 18 papers in renowned journals, 12 as first author, 12 indexed by SCI
Publications
- Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1a., Lim S, Liu H, Madeira da Silva L, Arora R, Liu Z, Phillips JB, Schmitt DC, Vu T, McClellan S, Lin Y, Lin W, Piazza GA, Fodstad O, Tan M., 2016
- miR-125b functions as a key mediator for snail-induced stem cell propagation and chemoresistance., Liu Z, Liu H, Desai S, Schmitt DC, Zhou M, Khong HT, Klos KS, McClellan S, Fodstad O, Tan M., 2013
- Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism., Ding Y, Liu Z, Desai S, Zhao Y, Liu H, Pannell LK, Yi H, Wright ER, Owen LB, Dean-Colomb W, Fodstad O, Lu J, LeDoux SP, Wilson GL, Tan M., 2012
- Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism., Zhao Y, Liu H, Liu Z, Ding Y, LeDoux SP, Wilson GL, Voellmy R, Lin Y, Lin W, Nahta R, Liu B, Fodstad O, Chen J, Wu Y, Price JE, Tan M., 2011
- B7-H3 silencing increases paclitaxel sensitivity by abrogating Jak2/Stat3 phosphorylation., Liu H, Tekle C, Chen YW, Kristian A, Zhao YH, Zhou M, Liu ZX, Ding Y, Wang B, M?landsmo GM, Fodstad O, Tan M., 2011
- Emerging metabolic targets in cancer therapy., Zhao Y, Liu H, Riker AI, Fodstad O, Ledoux SP, Wilson GL, Tan M., 2011
- Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth., Zhao YH, Zhou M, Liu H, Ding Y, Khong HT, Yu D, Fodstad O, Tan M., 2009
- Inhibition of lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol., Zhou M, Zhao Y, Ding Y, Liu H, Liu Z, Fodstad O, Riker AI, Kamarajugadda S, Lu J, Owen LB, Ledoux SP, Tan M., 2010
- MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic BCL-2 antagonist killer 1 (BAK1) expression., Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y, Xiong W, Li G, Lu J, Fodstad O, Riker AI, Tan M., 2010
Awards
- Sichuan University Young Backbone Teacher Award
- Sichuan University Excellent Quality of Classroom Teaching Award
