Upload Avatar (500 x 500)
Hongchi Yu
Basic Medicine and Forensic Medicine
Sichuan University
Sichuan
Language: Chinese, English
Biomechanics
Tumor
Cardiovascular
Disease
Mechanoreceptors
Signal Transduction
Therapeutic Systems
Proteolytic Targeting
Chimeras
Development
Areas of Focus
- Biomechanical regulation mechanisms in tumor/cardiovascular disease development
- Screening of novel cellular mechanoreceptors and their signal transduction mechanisms
- Development of therapeutic systems based on proteolytic targeting chimeras of cellular mechanoreceptors
Academic Background & Achievements
- 2017 - PhD in Biomedical Engineering: Sichuan University
- Postdoctoral Research: National Engineering Research Center for Biomaterials
Publications
- Interstitial Fluid Shear Stress Induces the Synthetic Phenotype Switching of Vsmcs to Release Pro-Calcified Extracellular Vesicles Via Egfr-Mapk-Klf5 Pathway, GaoWenbo, Gu Kaiyun, Ma Lunjie, Yang Fan, Deng Li, Zhang Yaojia, Miao Michael Z, Li Wenjun, Li Gang, Qian Hong, Zhang Zhen, Wang Guixue, Yu Hongchi, Liu Xiaoheng, 2024
- Integrating Anion–π+ Interaction and Crowded Conformation to Develop Multifunctional NIR AIEgen for Effective Tumor Theranostics via Hippo–YAP Pathway, Shiping Yang, Hongchi Yu, Junkai Liu, Lunjie Ma, Zhe Hou, Jia Ma, Michael Z. Miao, Ryan T. K. Kwok, Jianwei Sun, Herman H. Y. Sung, Ian D. Williams, Jacky W. Y. Lam, Xiaoheng Liu, Ben Zhong Tang, 2023
- Arsenic Trioxide Activates Yes-associated Protein by Lysophosphatidic Acid Metabolism to Selectively Induce Apoptosis of Vascular Smooth Muscle Cells, Hongchi Yu, Zhe Hou, Maolong Xiang, Fan Yang, Jia Ma, Li Yang, Xiaoyi Ma, Lifeng Zhou, Fugui He, Michael Miao, Xiaoheng Liu, Yunbing Wang, 2022
- Yes-associated Protein Contributes to Magnesium Alloy-derived Inflammation in Endothelial Cells, Hongchi Yu, Zhe Hou, Nuoya Chen, Rifang Luo, Li Yang, Michael Miao, Xiaoyi Ma, Lifeng Zhou, Fugui He, Yang Shen, Xiaoheng Liu, Yunbing Wang, 2022
- Fluid Shear Stress Activates YAP to Promote Epithelial-mesenchymal Transition in Hepatocellular Carcinoma, Hongchi Yu, Jia He, Guanyue Su, Yuelong Wang, Fei Fang, Wenxing Yang, Kaiyun Gu, Nai Yang Fu, Yunbing Wang, Yang Shen, Xiaoheng Liu, 2021
