Professor | Shuai Zhang | Asia Growth Partners

Name	Shuai Zhang
Contact Information	shuaizhang@mail.hzau.edu.cn
Language ability	English, Chinese
Province	Hubei

Name

Shuai Zhang

Contact Information

shuaizhang@mail.hzau.edu.cn

Language ability

English, Chinese

Province

Hubei

University/Lab Affiliation and Title	Huazhong Agricultural University
Faculty	Life Sciences
Academic Background & Achievements	2011/9-2016/11 Doctorate: Peking University, College of Chemistry and Molecular Engineering, Chemical Biology 2007/09-2011/06 Bachelor's: Wuhan University, College of Chemistry and Molecular Sciences, Applied Chemistry
Work Experience	2022/06-present - Huazhong Agricultural University, College of Biomedical and Health Sciences - Researcher and Doctoral Supervisor 2017/02-2022/04 - Cornell University, Department of Chemistry and Chemical Biology/Howard Hughes Medical Institute - Postdoctoral Researcher

University/Lab Affiliation and Title

Huazhong Agricultural University

Faculty

Life Sciences

Academic Background & Achievements

2011/9-2016/11 Doctorate: Peking University, College of Chemistry and Molecular Engineering, Chemical Biology
2007/09-2011/06 Bachelor's: Wuhan University, College of Chemistry and Molecular Sciences, Applied Chemistry

Work Experience

2022/06-present - Huazhong Agricultural University, College of Biomedical and Health Sciences - Researcher and Doctoral Supervisor
2017/02-2022/04 - Cornell University, Department of Chemistry and Chemical Biology/Howard Hughes Medical Institute - Postdoctoral Researcher

Areas of Focus	Development of precise regulation strategies for protein lipidation to combat aging and age-related diseases Identification of therapeutic lipidation targets related to aging and age-related diseases Creation of small molecule-based strategies for precise regulation of protein lipidation Establishment of new functional proteomics methods to characterize active small molecules and elucidate their mechanisms
Publications	Long-Chain Fatty Acyl Coenzyme A inhibits NME1/2 and regulates cancer metastasis, S Zhang, O. D. Nelson, I. R. Price, C. Zhu, I. R. Fernandez, X. Lu, R. S. Weiss, H. Lin, 2022 Comparative proteomics reveal distinct chaperone-client interactions in supporting bacterial acid resistance, S. Zhang, D. He, Y. Yang, S. Lin, M. Zhang, S. Dai, P. R. Chen, 2016 Conditional chaperone–client interactions revealed by genetically encoded photo-cross-linkers, S. Zhang, D. He, Z. Lin, Y. Yang, H. Song, P. R. Chen, 2017 Global Profiling of Sirtuin Deacylase Substrates Using a Chemical Proteomic Strategy and Validation by Fluorescent Labeling, S. Zhang, N. A. Spiegelman, H. N. Lin, 2019 NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle, Kosciuk, T., I. R. Price, X. Zhang, C. Zhu, K. N. Johnson, S. Zhang, S. L. Halaby, G. P. Komaniecki, M. Yang, C. J. DeHart, P. M. Thomas, N. L. Kelleher, J. C. Fromme, H. Lin, 2020 Genetically encoded cleavable and mass spectrometry-identifiable Protein photocrosslinker, Y. Yang, H. Song, D. He, S. Zhang, S. Lin, S. Dai, R. Meng, C. Wang, P. R. Chen, 2016 Genetically encoded releasable photo-cross-linking strategies for studying protein–protein interactions in living cells, Y. Yang, H. Song, D. He, S. Zhang, S. Dai, X. Xie, P. R. Chen, 2017 Genetically encoded cleavable protein photocrosslinker, S. Lin, D. He, T. Long, S. Zhang, R. Meng, P. R. Chen, 2014 First implementation of alkaline polymer electrolyte water electrolysis working only with pure water, L. Xiao, S. Zhang, J. Pan, C. Yang, M. He, L Zhuang, J. Lu, 2012

Areas of Focus

Development of precise regulation strategies for protein lipidation to combat aging and age-related diseases
Identification of therapeutic lipidation targets related to aging and age-related diseases
Creation of small molecule-based strategies for precise regulation of protein lipidation
Establishment of new functional proteomics methods to characterize active small molecules and elucidate their mechanisms

Publications

Long-Chain Fatty Acyl Coenzyme A inhibits NME1/2 and regulates cancer metastasis, S Zhang, O. D. Nelson, I. R. Price, C. Zhu, I. R. Fernandez, X. Lu, R. S. Weiss, H. Lin, 2022
Comparative proteomics reveal distinct chaperone-client interactions in supporting bacterial acid resistance, S. Zhang, D. He, Y. Yang, S. Lin, M. Zhang, S. Dai, P. R. Chen, 2016
Conditional chaperone–client interactions revealed by genetically encoded photo-cross-linkers, S. Zhang, D. He, Z. Lin, Y. Yang, H. Song, P. R. Chen, 2017
Global Profiling of Sirtuin Deacylase Substrates Using a Chemical Proteomic Strategy and Validation by Fluorescent Labeling, S. Zhang, N. A. Spiegelman, H. N. Lin, 2019
NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle, Kosciuk, T., I. R. Price, X. Zhang, C. Zhu, K. N. Johnson, S. Zhang, S. L. Halaby, G. P. Komaniecki, M. Yang, C. J. DeHart, P. M. Thomas, N. L. Kelleher, J. C. Fromme, H. Lin, 2020
Genetically encoded cleavable and mass spectrometry-identifiable Protein photocrosslinker, Y. Yang, H. Song, D. He, S. Zhang, S. Lin, S. Dai, R. Meng, C. Wang, P. R. Chen, 2016
Genetically encoded releasable photo-cross-linking strategies for studying protein–protein interactions in living cells, Y. Yang, H. Song, D. He, S. Zhang, S. Dai, X. Xie, P. R. Chen, 2017
Genetically encoded cleavable protein photocrosslinker, S. Lin, D. He, T. Long, S. Zhang, R. Meng, P. R. Chen, 2014
First implementation of alkaline polymer electrolyte water electrolysis working only with pure water, L. Xiao, S. Zhang, J. Pan, C. Yang, M. He, L Zhuang, J. Lu, 2012

Protein Lipidation Aging Age-Related Diseases Therapeutic Targets Small Molecules Functional Proteomics Regulation Strategies Health Aging Intervention Treatment

Hongbing Wang - Tongji University

Hongbing Wang - Tongji University

Hongbing Wang - Tongji University

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