1995-1999: Bachelor's in Biochemistry, Sun Yat-sen University
1999-2002: Master's in Biochemistry and Molecular Biology, Sun Yat-sen University
2002-2005: PhD in Biochemistry and Molecular Biology, Sun Yat-sen University
Published 44 papers in SCI journals as corresponding or first author
2003-2004: Visiting Scholar, Hong Kong University of Science and Technology
2005.11-2008.10: Postdoctoral Researcher, University of Tennessee, USA
2008.11-2014.8: Research Fellow, Harvard Medical School/Massachusetts General Hospital, USA
2014-present: Professor and Doctoral Supervisor, School of Life Sciences, Sun Yat-sen University
2018-present: Head of Department of Biological Sciences and Technology
2014: National 'Overseas High-level Talent Introduction Program' Youth Project
2015: National Excellent Young Scientists Fund
2021: National Outstanding Youth Science Fund
Research
Plant immune signal transduction Plant targeted gene regulation technology
A dual-function selection system enables positive selection of multigene CRISPR mutants and negative selection of Cas9-free progeny in Arabidopsis., Wang FZ, Bao Y, Li Z, Xiong X, Li JF, 2024
Identification and application of an exocarp-preferential promoter for genetic engineering of tomato fruit., Ruan XM, Xiong X, Li JF, 2024
Hidden prevalence of deletion-inversion bi-alleles in CRISPR-mediated deletions of tandemly arrayed genes in plants., Liu J, Wang FZ, Li C, Li Y, Li JF, 2023
Split complementation of base editors to minimize off-target edits., Xiong X, Liu K, Li Z, Xia FN, Ruan XM, He X, Li JF, 2023
WeiTsing: a new face of Ca2+-permeable channels in plant immunity., Wang FZ, Li JF, 2023
Plasma membrane-nucleo-cytoplasmic coordination of a receptor-like cytoplasmic kinase promotes EDS1-dependent plant immunity., Li Y, Xue J, Wang FZ, Huang X, Gong BQ, Tao Y, Shen W, Tao K, Yao N, Xiao S, Zhou JM, Li JF, 2022
A cytosine base editor toolkit with varying activity windows and target scopes for versatile gene manipulation in plants., Xiong X, Li Z, Liang J, Liu K, Li C, Li JF, 2022
Plant elicitor peptide signalling confers rice resistance to piercing-sucking insect herbivores and pathogens., Shen W, Zhang X, Liu J, Tao K, Li C, Xiao S, Zhang W, Li JF, 2022
Overexpression of an Osa-miR162a derivative in rice confers cross-kingdom RNA interference-mediated brown planthopper resistance without perturbing host development., Shen W, Cao S, Liu J, Zhang W, Chen J, Li JF, 2021
Receptor-like cytoplasmic kinase CDG1 negatively regulates Arabidopsis pattern-triggered immunity and is involved in AvrRpm1-induced RIN4 phosphorylation., Yang Q, Guo J, Zeng H, Xu L, Xue J, Xiao S, Li JF, 2021
Arabidopsis lysin motif/F-box-containing protein InLYP1 fine-tunes glycine metabolism by degrading glycine decarboxylase GLDP2., Guo J, Gong BQ, Li JF, 2021
Multiplex and optimization of dCas9-TV-mediated gene activation in plants., Xiong X, Liang J, Li Z, Gong BQ, Li JF, 2021
Hide-and-seek: Chitin-triggered plant immunity and fungal counterstrategies., Gong BQ, Wang FZ, Li JF, 2020
Split Nano luciferase complementation for probing protein-protein interactions in plant cells., Wang FZ, Zhang N, Guo Y, Gong BQ, Li JF, 2020
Engineering plants to secrete affinity-tagged pathogen elicitors for deciphering immune receptor complex or inducing enhanced immunity., Miao S, Liu J, Guo J, Li JF, 2020
BAK1-mediated phosphorylation of canonical G protein alpha during flagellin signaling in Arabidopsis., Xue J, Gong BQ, Yao X, Huang X, Li JF, 2020
The working dead: repurposing inactive CRISPR-associated nucleases as programmable transcriptional regulators in plants., Li Z, Xiong X, Li JF, 2020
Cross-microbial protection via priming a conserved immune co-receptor through juxtamembrane phosphorylation in plants., Gong BQ, Guo J, Zhang N, Yao X, Wang HB, Li JF, 2019
Type-II metacaspases mediate the processing of plant elicitor peptides in Arabidopsis., Shen W, Liu J, Li JF, 2019
Engineered artificial microRNA precursors facilitate cloning and gene silencing in Arabidopsis and rice., Zhang D, Zhang N, Shen W, Li JF, 2019
Gene disruption through base editing-induced messenger RNA missplicing in plants., Li Z, Xiong X, Wang F, Liang J, Li JF, 2019
Dynamic G protein alpha signaling in Arabidopsis innate immunity., Xu L, Yao X, Zhang N, Gong BQ, Li JF, 2019
Enhanced protoplast assay by transfecting PCR-assembled gene expression cassettes with telomeric repeats and thiophosphate modifications., Huang X, Xue J, Wang F, Li JF, 2019
New cytosine base editor for plant genome editing., Li Z, Xiong X, Li JF, 2018
Engineering artificial microRNAs for multiplex gene silencing and simplified transgenic screen., Zhang N, Zhang D, Chen SL, Gong BQ, Guo Y, Xu L, Zhang XN, Li JF, 2018
A tyrosine phosphorylation cycle regulates fungal activation of a plant receptor Ser/Thr kinase., Liu J, Liu B, Chen S, Gong BQ, Chen L, Zhou Q, Xiong F, Wang M, Feng D, Li JF, Wang HB, Wang J, 2018
A potent Cas9-derived gene activator for plant and mammalian cells., Li Z, Zhang D, Xiong X, Yan B, Xie W, Sheen J, Li JF, 2017
Rice chitin receptor OsCEBiP is not a transmembrane protein but targets to plasma membrane via a GPI anchor., Gong BQ, Xue J, Zhang N, Xu L, Yao X, Yang QJ, Yu Y, Wang HB, Zhang D, Li JF, 2017
A novel RNA-guided RNA-targeting CRISPR tool., Zhang D, Li Z, Yan B, Li JF, 2016
DNA-guided genome editing tool., Zhang D, Li JF, 2016
Targeted gene manipulation in plants using the CRISPR/Cas technology., Zhang D, Li Z, Li JF, 2016
Genome editing: New antiviral weapon for plants., Zhang D, Li Z, Li JF, 2015
Pathogen-secreted proteases activate a novel plant immune pathway., Cheng ZY, Li JF, Niu Y, Zhang XC, Woody OZ, Xiong Y, Djonovic S, Millet Y, Bush J, McConkey BJ, Sheen J, Ausubel FM, 2015
Epitope-tagged protein-based artificial microRNA screens for optimized gene silencing in plants., Li JF, Zhang D, Sheen J, 2014
Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9., Li JF, Norville JE, Aach J, McCormack M, Zhang DD, Bush J, Church GM, Sheen J, 2013
Comprehensive artificial microRNA screens for effective gene silencing in plants., Li JF, Chung HS, Niu Y, Bush J, Sheen J, 2013
Lysin motif-containing proteins LYP4 and LYP6 play dual roles in peptidoglycan and chitin perception in rice innate immunity., Liu B, Li JF, Ao Y, Qu J, Li Z, Su J, Zhang Y, Liu J, Feng D, Qi K, He Y, Wang J, Wang HB, 2012
High-throughput protein-protein interaction analysis in Arabidopsis mesophyll protoplasts by split firefly luciferase complementation., Li JF, Bush J, Xiong Y, Li L, McCormack M, 2011
A rapid and economical procedure for purification of plasmid or plant DNA with diverse applications in plant biology., Li JF, Li L, Sheen J, 2010
The FAST technique: a simplified Agrobacterium-based transformation method for transient gene expression analysis in seedlings of Arabidopsis and other plant species., Li JF, Park E, von Arnim AG, Nebenführ A, 2009
Interdependence of dimerization and organelle binding in myosin XI., Li JF, Nebenführ A, 2008
The tail that wags the dog: the globular tail domain defines the function of myosin V/XI., Li JF, Nebenführ A, 2008
Organelle targeting of myosin XI is mediated by two globular tail subdomains with separate cargo binding sites., Li JF, Nebenführ A, 2007
Tyr152 plays a central role in catalysis of 1-aminocyclopropane-1-carboxylate synthase., Li JF, Qu LH, Li N, 2005
Cleavages of the carboxyl-terminus of LeACS2, a tomato ACC synthase isomer, by a 64-kDa tomato metalloprotease produce a truncated but active enzyme., Li JF, Qi R, Qu LH, Mattoo AK, Li N, 2005
Isolation of a tomato protease that may be involved in proteolysis of 1-aminocyclopropane-1-carboxylate synthase., Li JF, Qu LH, Li N, 2005
Targeted transcriptional activation in plants using a potent dead Cas9-derived synthetic gene activator., Li Z, Wang F, Li JF, 2019
A simple protoplast-based method for screening potent artificial miRNA for maximal gene silencing in Arabidopsis., Zhang N, Zhang D, Li JF, 2016
Targeted plant genome editing via the CRISPR/Cas9 technology., Li JF, Zhang D, Sheen J, 2015
Quantitative protein-protein interaction analysis by split firefly luciferase complementation in plant protoplasts., Li JF, Zhang D, Sheen J, 2014
Cas9-based genome editing in Arabidopsis and Tobacco., Li JF, Zhang D, Sheen J, 2014
DNA purification from multiple sources in plant research with homemade silica resins., Li JF, Sheen J, 2012
FAST technique for Agrobacterium-mediated transient gene expression in seedlings of Arabidopsis and other plant species., Li JF, Nebenführ A, 2010
Area of Focus
Peptides | Biochemistry | Pharmaceuticals | Drug Development | Pdt | Cancer Research | Molecular Biology | Chemical Synthesis | Protein Engineering | Therapeutics
