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Bo Peng
Life Sciences
Sun Yat-Sen University
Guangdong
Language: Chinese, English
Contact
Bacterial Resistance Metabolic Regulation Antibiotic Sensitivity Metabolomics Metabolic State Antibiotic Entry Intracellular Concentration Bacterial Killing Host Biomarkers Energy Cycle
Areas of Focus
  • Bacterial resistance and metabolic regulation
Academic Background & Achievements
  • Achievement: Long-term research on bacterial resistance and metabolic regulation.
  • Achievement: Discovery of the pyruvate cycle providing energy in bacteria.
Publications
  • Exogenous alanine and or/glucose plus kanamycin kills antibiotic-resistant bacteria, Peng B, Su YB, Li H, Han Y, Guo C, Tian YM, Peng XX, 2015
  • Pyruvate cycle increases aminoglycoside efficacy and provides respiratory energy in bacteria, Su YB, Peng B, Li H, Cheng ZX, Zhang TT, Zhu JX, Li D, Li MY, Ye JZ, Du CC, Zhang S, Zhao XL, Yang MJ, Peng XX, 2018
  • Alanine enhances aminoglycosides-induced ROS production as revealed by proteomic analysis, Ye JZ, Su YB, Lin XM, Lai SS, Li WX, Ali F, Zheng J, Peng B, 2018
  • Analysis of global prevalence of antibiotic resistance in Acinetobacter baumannii infections disclosed a faster increase in OECD countries, Xie RQ, Zhang XH, Zhao Q, Peng B, Zheng J, 2018
  • Identification and efficacy of glycine serine and threonine metabolism in potentiating kanamycin-mediated killing of Edwardsiella piscicida, Ye JZ, Lin XM, Cheng ZX, Su YB, Li WX, Ali F, Zheng J, Peng B, 2018
  • Edwardsiella tarda tunes tricarboxylic acid cycle to evade complement-mediated killing, Cheng ZX, Gong QY, Wang Z, Chen ZG, Ye JZ, Li J, Wang J, Yang MJ, Ling XP, Peng B, 2017
  • Interactome of E.piscicida and grouper liver proteins reveals strategies of bacterial infection and host immune response, Li H, Zhu QF, Peng XX, Peng B, 2017
  • Glucose enhances tilapia against Edwardsiella tarda infection through metabolome reprogramming, Zeng ZH, Du CC, Liu SR, Li H, Peng XX, Peng B, 2017
  • Outer membrane proteins form specific patterns in antibiotic-resistant Edwardsiella tarda, Peng B, Wang C, Li H, Su YB, Ye JZ, Yang MJ, Jiang M, Peng XX, 2017
  • C-terminal domain of hemocyanin, a major antimicrobial protein from Litopenaeus vannamei: structural homology with immunoglobulins and molecular diversity, Zhang YL, Peng B, Li H, Yan F, Wu HK, Zhao XL, Lin XM, Min SY, Gao YY, Wang SY, Li YY, Peng XX, 2017
  • Exogenous L-valine promotes phagocytosis to kill multidrug-resistant bacterial pathogens, Chen XH, Liu SR, Peng B, Li D, Cheng ZX, Zhu JX, Zhang S, Peng YM, Li H, Zhang TT, Peng XX, 2017
  • Metabolic mechanism for L-Leucine-induced metabolome to eliminate Streptococcus iniae, Du CC, Yang MJ, Li MY, Yang J, Peng B, Li H, Peng XX, 2017
  • DNA shuffling approach for recombinant polyvalent OmpAs against V. alginolyticus and E.tarda infections, Li H, Chu X, Peng B, Peng XX, 2016
  • Fructose promotes growth and antifungal activity of Penicillium citrinum, Wu CW, Wu X, Wen C, Peng B, Peng XX, Chen XH, Li H, 2016
  • GC-MS-based metabolome and metabolite regulation in serum-resistant Streptococcus agalactiae, Wang Z, Li MY, Peng B, Cheng ZX, Li H, Peng XX, 2016
  • Identification of polyvalent protective immunogens from outer membrane proteins in Vibrio paraheamolyticus to protect fish against bacterial infection, Peng B, Ye JZ, Han Y, Zeng L, Zhang JY, Li H, 2016
  • Identification of the interactome between fish plasma proteins and Edwardsiella tarda reveals tissue-specific strategies against bacterial infection, Li H, Huang X, Zeng Z, Peng XX, Peng B, 2016
  • TolC plays a crucial role in immune protection conferred by Edwardsiella tarda whole-cell vaccines, Wang C, Peng B, Li H, Peng XX, 2016
  • Dyanmic metabolic change is indicative of inflammation-induced transformation of hepatic cells, Peng B, Liu F, Han R, Luo G, Cathopoulis T, Lu K, Li X, Yang L, Liu GY, Cai JC, Shi SL, 2015
  • Functional metabolomics: from biomarker discovery to metabolome reprogramming, Peng B, Li H, Peng XX, 2015
  • Metabolome strategy against Edwardesiella tarda infection through glucose-enhanced metabolic modulation in talapias, Peng B, Ma YM, Zhang JY, Li H, 2015
  • Fructose restores susceptibility of multidrug-resistant Edwardesilla tarda to kanamycin, Su YB, Peng B, Han Y, Li H, Peng XX, 2015
  • Live Edwardsiella tarda vaccine enhances innate immunity by metabolic modulation in Zebrafish, Guo C, Peng B, Song M, Wu CW, Yang MJ, Zhang JY, Li H, 2015
Awards
  • Excellent Youth Science Fund (2019)
  • General Projects (2016, 2018)
  • Key R&D Sub-project (2016)
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