Professor | Li-Min Zheng | Asia Growth Partners

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Name	Li-Min Zheng
Contact Information	zhenglm@mail.sysu.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Li-Min Zheng

Contact Information

zhenglm@mail.sysu.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Sun Yat-Sen University
Faculty	Life Sciences
Academic Background & Achievements	1979-1984: Bachelor in Medicine, Shanghai Medical University 1990-1994: PhD in Immunology, Leiden University, Netherlands Published over 90 papers in international journals with a total impact factor of approximately 800 Recipient of National Science Foundation key projects and Ministry of Health major projects
Work Experience	1984-1990: Doctor at Huashan Hospital, Shanghai Medical University 1994-1996: Postdoctoral Researcher, Department of Cell Biology, Linkoping University, Sweden 1996-1998: Postdoctoral Researcher, Malmo General Hospital, Lund University, Sweden 1999-2002: Assistant Professor, Department of Medical Microbiology, Linkoping University, Sweden 2002-2016: Professor and Doctoral Supervisor, School of Life Sciences, Sun Yat-sen University 2016-present: Dean, School of Life Sciences, Sun Yat-sen University
Awards	2004: National Outstanding Youth 2014: Selected as one of Guangdong's 'Top 100 Talents' 2016: 13th Guangdong Ding Ying Science and Technology Award

University/Lab Affiliation and Title

Sun Yat-Sen University

Faculty

Life Sciences

Academic Background & Achievements

1979-1984: Bachelor in Medicine, Shanghai Medical University
1990-1994: PhD in Immunology, Leiden University, Netherlands
Published over 90 papers in international journals with a total impact factor of approximately 800
Recipient of National Science Foundation key projects and Ministry of Health major projects

Work Experience

1984-1990: Doctor at Huashan Hospital, Shanghai Medical University
1994-1996: Postdoctoral Researcher, Department of Cell Biology, Linkoping University, Sweden
1996-1998: Postdoctoral Researcher, Malmo General Hospital, Lund University, Sweden
1999-2002: Assistant Professor, Department of Medical Microbiology, Linkoping University, Sweden
2002-2016: Professor and Doctoral Supervisor, School of Life Sciences, Sun Yat-sen University
2016-present: Dean, School of Life Sciences, Sun Yat-sen University

Awards

2004: National Outstanding Youth
2014: Selected as one of Guangdong's 'Top 100 Talents'
2016: 13th Guangdong Ding Ying Science and Technology Award

Areas of Focus	Tumor Immunology Immunocellular Biology
Publications	Peritumoral monocytes induce cancer cell autophagy to facilitate the progression of human hepatocellular carcinoma, DP Chen, WR Ning, XF Li, Y Wei, XM Lao, JC Wang, Y Wu and L Zheng, 2018 Monocytes /Macrophages promote vascular CXCR4 expression via the ERK pathway in hepatocellular carcinoma, YM Meng, J Liang, C Wu, J Xu, DN Zeng, XJ Yu, H Ning, L Xu, and L Zheng, 2018 Vascular CXCR4 expression promotes vessel sprouting and sensitivity to Sorafenib treatment in hepatocellular carcinoma, J Xu, J Liang, YM Meng, J Yan, XJ Yu, CQ Liu, L Xu, SM Zhuang and L Zheng, 2017 CD169 identifies an activated CD8 T cell subset in regional lymph nodes that predicts favorable prognosis in colorectal cancer patients, J Zhang, J Xu, RX Zhang, Y Zhang, QJ Ou, JQ Li, ZZ Jiang, XJ Wu, YJ Fang, and L Zheng, 2016 CD169 identifies an anti-tumour macrophage subpopulation in human hepatocellular carcinoma, Y Zhang, JQ Li, ZZ Jiang, L Li, Y Wu, and L Zheng, 2016 c-Met identifies a population of matrix metalloproteinase 9-producing monocytes in peritumoral stroma of Hepatocellular carcinoma, L Zhao, Y Wu, XD Xie, YF Chu, JQ Li, and L Zheng, 2015 Increased autophagy sustains the survival and protumorigenic effects of neutrophils in human cancers, XF Li, DP Chen, FZ Ouyang, MM Chen, Y Wu, DM Kuang, and L Zheng, 2015 B7-H1-expressing antigen-presenting cells mediate polarization of pro-tumorigenic Th22 subset, DM Kuang, X Xiao, Q Zhao, MM Chen, XF Li, RX Liu, Y Wei, FZ Ouyang, DP Chen, Y Wu, XM Lao, H Deng, and L Zheng, 2014 Circulating hematopoietic stem and progenitor cells are myeloid-biased in cancer patients, WC Wu, HW Sun, HT Chen, J Liang, XJ Yu, C Wu, Z Wang, and L Zheng, 2014 Monocyte /Macrophage-elicited NK cell dysfunction in Hepatocellular carcinoma is mediated by CD48/2B4 interactions, Y Wu, DM Kuang, WD Pan, YL Wan, XM Lao, D Wang, XF Li, L Zheng, 2013 In Situ molecular signature predict early recurrence in Hepatitis B virus-related hepatocellular carcinoma, J Xu, T Ding, Q He, X Yu, W Wu, W Jia, J Yun, Y Zhang, M Shi, C Shao, WD Pan, X Yin, J Min, SM Zhuang, L Zheng, 2012 Activated CD69+ T cells foster immune privilege by regulating IDO expression in tumor-associated macrophages, Q Zhao, DM Kuang, Y Wu, X Xiao, X Li, T Li, L Zheng, 2012 Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma, DM Kuang, Q Zhao, Y Wu, C Peng, J Wang, Z Xu, X Yin, L Zheng, 2011 Tumor activated monocytes promote expansion of IL-17-producing CD8+ T cells in hepatocellular carcinoma patients, DM Kuang, C Peng, Q Zhao, Y Wu, MS Chen, L Zheng, 2010 Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory Th17 cells, DM Kuang, C Peng, Q Zhao, Y Wu, MS Chen, L Zheng, 2010 Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients, JP Zhang, J Yan, J Xu, XH Pang, MS Chen, L Li, C Wu, SP Li, L Zheng, 2009 Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients, J Zhou, T Ding, LY Zhu, W Pan, L Li, L Zheng, 2009 Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1, DM Kuang, QY Zhao, C Peng, J Xu, JP Zhang, L Zheng, 2009

Areas of Focus

Tumor Immunology
Immunocellular Biology

Publications

Peritumoral monocytes induce cancer cell autophagy to facilitate the progression of human hepatocellular carcinoma, DP Chen, WR Ning, XF Li, Y Wei, XM Lao, JC Wang, Y Wu and L Zheng, 2018
Monocytes /Macrophages promote vascular CXCR4 expression via the ERK pathway in hepatocellular carcinoma, YM Meng, J Liang, C Wu, J Xu, DN Zeng, XJ Yu, H Ning, L Xu, and L Zheng, 2018
Vascular CXCR4 expression promotes vessel sprouting and sensitivity to Sorafenib treatment in hepatocellular carcinoma, J Xu, J Liang, YM Meng, J Yan, XJ Yu, CQ Liu, L Xu, SM Zhuang and L Zheng, 2017
CD169 identifies an activated CD8 T cell subset in regional lymph nodes that predicts favorable prognosis in colorectal cancer patients, J Zhang, J Xu, RX Zhang, Y Zhang, QJ Ou, JQ Li, ZZ Jiang, XJ Wu, YJ Fang, and L Zheng, 2016
CD169 identifies an anti-tumour macrophage subpopulation in human hepatocellular carcinoma, Y Zhang, JQ Li, ZZ Jiang, L Li, Y Wu, and L Zheng, 2016
c-Met identifies a population of matrix metalloproteinase 9-producing monocytes in peritumoral stroma of Hepatocellular carcinoma, L Zhao, Y Wu, XD Xie, YF Chu, JQ Li, and L Zheng, 2015
Increased autophagy sustains the survival and protumorigenic effects of neutrophils in human cancers, XF Li, DP Chen, FZ Ouyang, MM Chen, Y Wu, DM Kuang, and L Zheng, 2015
B7-H1-expressing antigen-presenting cells mediate polarization of pro-tumorigenic Th22 subset, DM Kuang, X Xiao, Q Zhao, MM Chen, XF Li, RX Liu, Y Wei, FZ Ouyang, DP Chen, Y Wu, XM Lao, H Deng, and L Zheng, 2014
Circulating hematopoietic stem and progenitor cells are myeloid-biased in cancer patients, WC Wu, HW Sun, HT Chen, J Liang, XJ Yu, C Wu, Z Wang, and L Zheng, 2014
Monocyte /Macrophage-elicited NK cell dysfunction in Hepatocellular carcinoma is mediated by CD48/2B4 interactions, Y Wu, DM Kuang, WD Pan, YL Wan, XM Lao, D Wang, XF Li, L Zheng, 2013
In Situ molecular signature predict early recurrence in Hepatitis B virus-related hepatocellular carcinoma, J Xu, T Ding, Q He, X Yu, W Wu, W Jia, J Yun, Y Zhang, M Shi, C Shao, WD Pan, X Yin, J Min, SM Zhuang, L Zheng, 2012
Activated CD69+ T cells foster immune privilege by regulating IDO expression in tumor-associated macrophages, Q Zhao, DM Kuang, Y Wu, X Xiao, X Li, T Li, L Zheng, 2012
Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma, DM Kuang, Q Zhao, Y Wu, C Peng, J Wang, Z Xu, X Yin, L Zheng, 2011
Tumor activated monocytes promote expansion of IL-17-producing CD8+ T cells in hepatocellular carcinoma patients, DM Kuang, C Peng, Q Zhao, Y Wu, MS Chen, L Zheng, 2010
Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory Th17 cells, DM Kuang, C Peng, Q Zhao, Y Wu, MS Chen, L Zheng, 2010
Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients, JP Zhang, J Yan, J Xu, XH Pang, MS Chen, L Li, C Wu, SP Li, L Zheng, 2009
Increased intratumoral regulatory T cells are related to intratumoral macrophages and poor prognosis in hepatocellular carcinoma patients, J Zhou, T Ding, LY Zhu, W Pan, L Li, L Zheng, 2009
Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1, DM Kuang, QY Zhao, C Peng, J Xu, JP Zhang, L Zheng, 2009

Cancer Immunology Tumor Immune Cells Biochemistry Molecular Biology Cell Interaction Clinical Significance Liver Cancer Immune Regulation

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