Achievement: First to isolate, identify, and preserve highly virulent Vibrio vulnificus in eels in China
Achievement: Original contributions in the field of aquatic viruses such as iridovirus and herpesvirus
2005-present - Sun Yat-sen University - Associate Professor
2019: National Agricultural and Rural Ministry First Class New Veterinary Drug Certificate for inactivated vaccine against infectious spleen and kidney necrosis disease
Research
Pathobiology, vaccinology, and immunobiology of viral diseases in aquatic economic animals
The Inactivated ISKNV-I Vaccine Confers Highly Effective Cross-Protection against Epidemic RSIV-I and RSIV-II from Cultured Spotted Sea Bass Lateolabrax maculatus, Fu, W., Li, Y., Fu, Y., Zhang, W., Luo, P., Sun, Q., Yu F, Weng S, Li W He J & Dong, C*, 2023
A mandarinfish Siniperca chuatsi infection and vaccination model for SDDV and efficacy evaluation of the formalin-killed cell vaccine in yellowfin seabream Acanthopagrus latus, Fu, Y., Li, Y., Chen, J., Yu, F., Liu, X., Fu, W., Pan, H., Li, W., Weng S., He, J., Dong, C*, 2023
Production and characterization of monoclonal antibodies against mandarinfish ranavirus and first identification of pyloric caecum as the major target tissue, Zhang, W., Deng, H., Fu, Y., Fu, W., Weng, S., He, J., & Dong, C*, 2023
Effectively protecting Asian seabass Lates calcarifer from ISKNV-I, ISKNV-II, RSIV-II and SDDV by an inactivated ISKNV-I and SDDV bivalent vaccine, Fu, Y., Li, Y., Zhang W, Fu, W., Li W, Zhu Z, Weng, S., He, J., Dong, C*, 2023
Iron loss and hypoxia are involved in lethal Pseudomonas plecoglossicida infections in the orange-spotted grouper Epinephelus coioides, Sun Y, Weng S, Xu B, Dong C*., He J*, 2023
Development of two cell lines from yellowfin sea bream (Acanthopagrus latus) fin and brain suitable for propagating SDDV but not for ISKNV, MRV and GIV-R, Fu, Y., Li, Y., Liu, X., Fu, W., Weng, S., Yu, F., He, J., Dong, C*, 2022
Deleting ORF71L of infectious spleen and kidney necrosis virus (ISKNV) resulted in virulence attenuation in Mandarin fish, Zhang, H., Qi, H., Weng, S., He, J*., & Dong, C*, 2022
Cyclophilin A is incorporated into cyprinid herpesvirus 3 (CyHV-3) virion via interaction with envelope VP32 and facilitates CyHV-3 replication in in vitro, Liu, F., Weng, S., He, J., Dong, C*, 2022
Scale Drop Disease Virus Associated Yellowfin Seabream (Acanthopagrus latus) Ascites Diseases, Zhuhai, Guangdong, Southern China: The First Description, Fu Y, Li Y, Fu W, Su H, Zhang L, Huang C, Weng S, Yu F, He J*, Dong, C*, 2021
Pathogenicity and histopathology of infectious spleen and kidney necrosis virus genotype II (ISKNV-II) recovering from mass mortality of farmed Asian seabass, Lates calcarifer, in Southern China, Zhu Z, Duan C, Li Y, Huang C, Weng S, He J and Dong, C*, 2021
Characterization of a highly lethal barramundi (Lates calcarifer) model of Pseudomonas plecoglossicida infection, Sun Y, Zhu Z, Weng S, He J and Dong, C*, 2020
Epidemiological situation and phylogenetic relationship of Vibrio harveyi in marine-cultured fishes in China and Southeast Asia, Zhu Zhiming, Duan Chao, Dong, C*, Weng Shaoping and He Jianguo*, 2020
Widespread outbreaks of the emerging mandarinfish ranavirus (MRV) both in natural and ISKNV-FKC vaccinated mandarinfish Siniperca chuatsi in Guangdong, South China, 2017, Zhang W, Duan C, Weng S, He J and Dong, C*, 2020
Identification of outer membrane protein TolC as the major adhesin and potential vaccine candidate for Vibrio harveyi in hybrid grouper, Epinephelus fuscoguttatus (♀) × E. lanceolatus (♂), Zhu Z, Dong C*., Weng S., He J*, 2019
Genomic and biologic comparisons of cyprinid herpesvirus 3 strains, Gao Y, Suárez Nicolás M., Wilkie Gavin S., Dong C, Bergmann Sven, Lee Pei Yu Alison, Davison Andrew J., Vanderplasschen Alain F. C.* and Boutier Maxime, 2018
The high prevalence of pathogenic Vibrio harveyi with multiple antibiotic resistance in scale drop and muscle necrosis disease of the hybrid grouper, Epinephelus fuscoguttatus (♀) × E. lanceolatus (♂), in China, Zhu Z, Dong C*, Weng S and He J*, 2018
Occurrence of a lethal ranavirus in hybrid mandarin (Siniperca scherzeri × Siniperca chuatsi) in Guangdong, South China, Dong C*, Wang Z, Weng S and He J, 2017
Identification and expression analysis of cellular and viral microRNAs in CyHV3-infected KCF-1 cells, Lee X, Weng S, Zhang H, Zeng J, He J* and Dong C*, 2016
Differential autophagic effects triggered by five different vertebrate iridoviruses in a common, highly permissive mandarinfish fry (MFF-1) cell model, Qi H, Yi Y, Weng S, Zou W, He J* and Dong C*, 2016
Transcriptomic analysis of koi (Cyprinus carpio) spleen tissue upon cyprinid herpesvirus 3 (CyHV3) infection using next generation sequencing, Lee X, Yi Y, Weng S, Zeng J, Zhang H, He J* and Dong C*, 2016
Functional characterization of viral tumor necrosis factor receptors encoded by cyprinid herpesvirus 3 (CyHV3) genome, Yi, Y., Qi, H., Yuan, J., Wang, R., Weng, S., He, J., Dong, C*, 2015
Whole-genome sequence of a novel Chinese cyprinid herpesvirus 3 isolate reveals the existence of a distinct European genotype in East Asia, Li, W., Lee, X., Weng, S., He, J*., Dong, C*, 2015
Cloning of a new fibroblast cell line from an early primary culture from mandarin fish(Siniperca chuatsi) fry for efficient proliferation of megalocytiviruses, Dong C*, Shuang F, Weng S and He J, 2014
Extracellular virion proteins of two Chinese CyHV-3/KHV isolates, and identification of two novel envelope proteins, Yi Y, Zhang H, Lee X, Weng S, He J and Dong C*, 2014
Identification and characterization of a novel FstK-like protein from spotted knifejaw iridovirus (genus Megalocytivirus), Xiang Z, Weng S, Qi H, He J and Dong C*, 2014
Virion-associated viral proteins of a Chinese giant salamander (Andrias davidianus) iridovirus (genus Ranavirus) and functional study of the major capsid protein (MCP), Li, W., Zhang, X., Weng, S., Zhao, G., He, J., Dong, C*, 2014
Emergence of fatal European genotype CyHV-3/KHV in mainland China, Dong C*, Li X, Weng S, Xie S and He J*, 2013
Virion proteins of an RSIV type megalocytivirus from spotted knifejaw Oplegnathus punctatus (SKIV-ZJ07), Shuang F, Luo Y, Xiong X, Weng S, Li Y, He J*, and Dong C**, 2013
Efficacy of a formalin-killed cell vaccine against infectious spleen and kidney necrosis virus (ISKNV) and immunoproteomic analysis of its major immunogenic proteins, Dong C, Xiong X, Luo Y, Weng S, Wang Q and He J*, 2013
Field trial tests of FKC vaccines against RSIV genotype Megalocytivirus in cage-cultured mandarin fish (Siniperca chuatsi) in an inland reservoir, Dong, Y., Weng, S., He, J., Dong, C*, 2013
Characterization of a new cell line from caudal fin of koi, Cyprinus carpio koi, and first isolation of cyprinid herpesvirus 3 in China, Dong C, Weng S, Li W, Li X, Yi Y, Liang Q, He J*, 2011
Global landscape of structural proteins of infectious spleen and kidney necrosis virus, Dong C, Xiong X, Shuang F, Weng S, Zhang J, Zhang Y, Luo Y, He J*, 2011
Characteristics of the interferon regulatory factor pairs zfIRF5/7 and their stimulation expression by ISKNV Infection in zebrafish (Danio rerio), Xiang Z, Dong C (Co-first authors), Qi L, Chen W, Huang L, Li Z, Xia Q, Liu D, Huang M, Weng S, He J*, 2010
Antigenic identification of virion structural proteins from infectious spleen and kidney necrosis virus, Xiong X, Dong C, Weng S, Zhang J, Zhang Y, He J*, 2011
Proteomic analysis of zebrafish (Danio rerio) infected with infectious spleen and kidney necrosis virus, Xiong X, Dong C, Xu X, Weng S, Liu Z, He J*, 2011
A new marine megalocytivirus from spotted knifejaw, Oplegnathus punctatus, and its pathogenicity to freshwater mandarinfish, Siniperca chuatsi, Dong C, Weng S, Luo Y, Huang M, Ai H, Yin Z, He J*, 2010
Development of a mandarin fish Siniperca chuatsi fry cell line suitable for the study of infectious spleen and kidney necrosis virus (ISKNV), Dong C, Weng S, Shi X, Xu X, Shi N, He J*, 2008
