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Haoyang Li
lihy88@mail.sysu.edu.cn
Chinese, English
Guangdong
Sun Yat-Sen University
Life Sciences
  • 2008.08-2012.06 Bachelor: Sun Yat-sen University, School of Life Sciences, Biological Sciences
  • 2012.09-2017.06 Doctorate: Sun Yat-sen University, School of Life Sciences, Aquatic Biology
  • Research on antiviral and antibacterial immunity in shrimp, achieving original research results
  • 2017.07-2019.06 - Sun Yat-sen University, School of Marine Sciences - Postdoctoral Researcher
  • 2019.08-2022.07 - Sun Yat-sen University, School of Marine Sciences - Specially Appointed Researcher
  • 2023.02-present - Sun Yat-sen University, School of Life Sciences - Associate Professor
Innate immunity and pathogen infection in aquatic invertebrates
Environmental stress and aquatic animal diseases
  • Genome assembly of redclaw crayfish (Cherax quadricarinatus) provides insights into its immune adaptation and hypoxia tolerance., Z Liu, J Zheng, H Li, K Fang, S Wang, J He, D Zhou, S Weng, M Chi, Z Gu, 2024
  • Nucleic Acid Sensing by STING Induces an IFN-like Antiviral Response in a Marine Invertebrate., H Li, X Di, S Wang, Q Li, S Weng, J He, C Li, 2024
  • Ammonia nitrogen stress increases susceptibility to bacterial infection via blocking IL-1R–Relish axis mediated antimicrobial peptides expression in shrimp., H Li, Q Li, S Wang, J He, C Li, 2023
  • The MIP-T3 from shrimp Litopenaeus vannamei restricts white spot syndrome virus infection via regulating NF-κB activation., H Li, Q Li, S Wang, J He, C Li, 2022
  • Stimulator of interferon genes (STING) defends against bacterial infection via IKKβ-mediated Relish activation in shrimp., H Li, Q Li, S Wang, J He, C Li, 2022
  • TNF-Receptor-Associated Factor 3 in Litopenaeus vannamei Restricts White Spot Syndrome Virus Infection Through the IRF-Vago Antiviral Pathway., H Li, Q Fu, S Wang, R Chen, X Jiang, P Zhu, J He, C Li, 2020
  • RNAi screening identifies a new Toll from shrimp Litopenaeus vannamei that restricts WSSV infection through activating Dorsal to induce antimicrobial peptides., H Li, B Yin, S Wang, Q Fu, B Xiao, K Lǚ, J He, C Li, 2018
  • An invertebrate STING from shrimp activates an innate immune defense against bacterial infection., H Li, S Wang, K Lǚ, B Yin, B Xiao, S Li, J He, C Li, 2017
  • Identification of two p53 isoforms from Litopenaeus vannamei and their interaction with NF-κB to induce distinct immune response., H Li, S Wang, Y Chen, K Lǚ, B Yin, S Li, J He, C Li, 2017
  • MKK6 from pacific white shrimp Litopenaeus vannamei is responsive to bacterial and WSSV infection., H Li, S Wang, Z Qian, Z Wu, K Lǚ, S Weng, J He, C Li, 2016
  • A C-type lectin (LvCTL4) from Litopenaeus vannamei is a downstream molecule of the NF-κB signaling pathway and participates in antibacterial immune response., H Li, Y Chen, M Li, S Wang, H Zuo, X Xu, S Weng, J He, C Li, 2015
  • Intestine bacterial community affects the growth of the Pacific white shrimp (Litopenaeus vannamei)., D Hou, B Yin, S Wang, H Li, S Weng, X Jiang, H Li, C Li, J He, Z Huang, 2024
  • Nitrite nitrogen stress disrupts the intestine bacterial community by altering host-community interactions in shrimp., D Hou, H Li, S Wang, S Weng, J He, 2024
  • Signaling events induced by lipopolysaccharide-activated Toll in response to bacterial infection in shrimp., S Wang, H Li, Q Li, B Yin, S Li, J He, C Li, 2023
  • An AhR–Caspase Axis Mediated Antiviral Apoptosis in an Arthropod., Q Fu, H Li, S Wang, X Liao, S Chen, B Xiao, R Chen, X Jiang, J He, C Li, 2022
  • Rap2a is negatively regulated by NF-κB and contributes to growth via wnt pathway in shrimp., S Wang, M He, Q Li, H Li, B Yin, J He, C Li, 2022
  • Interferon-Induced Protein 6-16 (IFI6-16) from Litopenaeus vannamei Regulate Antiviral Immunity via Apoptosis-Related Genes., K Lǚ, H Li, S Wang, A Li, S Weng, J He, C Li, 2022
  • TAK1 confers antibacterial protection through mediating the activation of MAPK and NF-κB pathways in shrimp., S Wang, H Li, R Chen, X Jiang, J He, C Li, 2022
  • Phenylalanine hydroxylase (PAH) plays a positive role during WSSV and Vibrio parahaemolyticus infection in Litopenaeus vannamei., Y Yao, L Shi, W Xiao, S Guo, S Liu, H Li, S Zhang, 2022
  • MAPKKK15 gene from shrimp litopenaeus vannamei is transcribed in larva development stages and contributes to WSSV pathogenesis., S Wang, H Li, P Zhu, Q Fu, B Yin, Q Li, R Chen, X Jiang, S Weng, J He, 2021
  • White spot syndrome virus establishes a novel IE1/JNK/c-Jun positive feedback loop to drive replication., S Wang, H Li, S Weng, C Li, J He, 2020
  • Molecular cloning, expression, promoter analysis and functional characterization of a new Crustin from Litopenaeus vannamei., M Li, C Ma, H Li, J Peng, D Zeng, X Chen, C Li, 2018
  • MKK4 from Litopenaeus vannamei is a regulator of p38 MAPK kinase and involved in anti-bacterial response., S Wang, B Yin, H Li, B Xiao, K Lǚ, C Feng, J He, C Li, 2018
  • Shrimp TAB1 interacts with TAK1 and p38 and activates the host innate immune response to bacterial infection., S Wang, M Li, B Yin, H Li, B Xiao, K Lǚ, Z Huang, S Li, J He, C Li, 2017
  • Identification and functional analysis of a TEP gene from a crustacean reveals its transcriptional regulation mediated by NF-κB and JNK pathways and its broad protective roles., C Li, H Li, B Xiao, Y Chen, S Wang, K Lǚ, B Yin, S Li, J He, 2017
  • Shrimp with knockdown of LvSOCS2, a negative feedback loop regulator of JAK/STAT pathway in Litopenaeus vannamei, exhibit enhanced resistance against WSSV., S Wang, X Song, Z Zhang, H Li, K Lǚ, B Yin, J He, C Li, 2016
  • Cloning, identification and functional analysis of a β-catenin homologue from Pacific white shrimp, Litopenaeus vannamei., S Zhang, L Shi, K Lǚ, H Li, S Wang, J He, C Li, 2016
  • Identification and characterization of transforming growth factor β-activated kinase 1 from Litopenaeus vannamei involved in anti-bacterial host defense., S Wang, H Li, K Lǚ, Z Qian, S Weng, J He, C Li, 2016
  • Identification and characterization of MKK7 as an upstream activator of JNK in Litopenaeus vannamei., S Wang, Z Qian, H Li, K Lǚ, X Xu, S Weng, J He, C Li, 2016
  • Activation of Vago by interferon regulatory factor (IRF) suggests an interferon system-like antiviral mechanism in shrimp., C Li, H Li, Y Chen, Y Chen, S Wang, SP Weng, X Xu, J He, 2015
  • Identification and functional characterization of the TAB2 gene from Litopenaeus vannamei., S Wang, H Li, Z Qian, X Song, Z Zhang, H Zuo, X Xu, S Weng, J He, C Li, 2015
  • The c-Fos and c-Jun from Litopenaeus vannamei play opposite roles in Vibrio parahaemolyticus and white spot syndrome virus infection., C Li, H Li, S Wang, X Song, Z Zhang, Z Qian, H Zuo, X Xu, S Weng, J He, 2015
  • Daxx from Pacific white shrimp Litopenaeus vannamei is involved in activation of NF-κB pathway., M Yan, J Tang, Q Liang, G Zhu, H Li, C Li, S Weng, J He, X Xu, 2015
  • A Janus Kinase in the JAK/STAT signaling pathway from Litopenaeus vannamei is involved in antiviral immune response., X Song, Z Zhang, S Wang, H Li, H Zuo, X Xu, S Weng, J He, C Li, 2015
  • Identification of a JAK/STAT pathway receptor domeless from Pacific white shrimp Litopenaeus vannamei., M Yan, C Li, Z Su, Q Liang, H Li, S Liang, S Weng, J He, X Xu, 2015
  • Identification and functional analysis of a Hemolin like protein from Litopenaeus vannamei., H Zuo, H Li, E Wei, Z Su, J Zheng, C Li, Y Chen, S Weng, J He, X Xu, 2015
  • Identification of a C-type lectin with antiviral and antibacterial activity from pacific white shrimp Litopenaeus vannamei., M Li, C Li, C Ma, H Li, H Zuo, S Weng, X Chen, D Zeng, J He, X Xu, 2014
  • Pellino protein from pacific white shrimp Litopenaeus vannamei positively regulates NF-κB activation., C Li, J Chai, H Li, H Zuo, S Wang, W Qiu, S Weng, J He, X Xu, 2014
  • Presence of Tube isoforms in Litopenaeus vannamei suggests various regulatory patterns of signal transduction in invertebrate NF-κB pathway., C Li, Y Chen, S Weng, S Li, H Zuo, X Yu, H Li, J He, X Xu, 2014
Innate Immunity Pathogen Infection Aquatic Invertebrates Environmental Stress Aquatic Diseases Shrimp Viral Immunity Bacterial Immunity Immune Pathways Molecular Mechanisms

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