2008.08-2012.06 Bachelor: Sun Yat-sen University, School of Life Sciences, Biological Sciences
2012.09-2017.06 Doctorate: Sun Yat-sen University, School of Life Sciences, Aquatic Biology
Research on antiviral and antibacterial immunity in shrimp, achieving original research results
2017.07-2019.06 - Sun Yat-sen University, School of Marine Sciences - Postdoctoral Researcher
2019.08-2022.07 - Sun Yat-sen University, School of Marine Sciences - Specially Appointed Researcher
2023.02-present - Sun Yat-sen University, School of Life Sciences - Associate Professor
Research
Innate immunity and pathogen infection in aquatic invertebrates Environmental stress and aquatic animal diseases
Genome assembly of redclaw crayfish (Cherax quadricarinatus) provides insights into its immune adaptation and hypoxia tolerance., Z Liu, J Zheng, H Li, K Fang, S Wang, J He, D Zhou, S Weng, M Chi, Z Gu, 2024
Nucleic Acid Sensing by STING Induces an IFN-like Antiviral Response in a Marine Invertebrate., H Li, X Di, S Wang, Q Li, S Weng, J He, C Li, 2024
Ammonia nitrogen stress increases susceptibility to bacterial infection via blocking IL-1R–Relish axis mediated antimicrobial peptides expression in shrimp., H Li, Q Li, S Wang, J He, C Li, 2023
The MIP-T3 from shrimp Litopenaeus vannamei restricts white spot syndrome virus infection via regulating NF-κB activation., H Li, Q Li, S Wang, J He, C Li, 2022
Stimulator of interferon genes (STING) defends against bacterial infection via IKKβ-mediated Relish activation in shrimp., H Li, Q Li, S Wang, J He, C Li, 2022
TNF-Receptor-Associated Factor 3 in Litopenaeus vannamei Restricts White Spot Syndrome Virus Infection Through the IRF-Vago Antiviral Pathway., H Li, Q Fu, S Wang, R Chen, X Jiang, P Zhu, J He, C Li, 2020
RNAi screening identifies a new Toll from shrimp Litopenaeus vannamei that restricts WSSV infection through activating Dorsal to induce antimicrobial peptides., H Li, B Yin, S Wang, Q Fu, B Xiao, K Lǚ, J He, C Li, 2018
An invertebrate STING from shrimp activates an innate immune defense against bacterial infection., H Li, S Wang, K Lǚ, B Yin, B Xiao, S Li, J He, C Li, 2017
Identification of two p53 isoforms from Litopenaeus vannamei and their interaction with NF-κB to induce distinct immune response., H Li, S Wang, Y Chen, K Lǚ, B Yin, S Li, J He, C Li, 2017
MKK6 from pacific white shrimp Litopenaeus vannamei is responsive to bacterial and WSSV infection., H Li, S Wang, Z Qian, Z Wu, K Lǚ, S Weng, J He, C Li, 2016
A C-type lectin (LvCTL4) from Litopenaeus vannamei is a downstream molecule of the NF-κB signaling pathway and participates in antibacterial immune response., H Li, Y Chen, M Li, S Wang, H Zuo, X Xu, S Weng, J He, C Li, 2015
Intestine bacterial community affects the growth of the Pacific white shrimp (Litopenaeus vannamei)., D Hou, B Yin, S Wang, H Li, S Weng, X Jiang, H Li, C Li, J He, Z Huang, 2024
Nitrite nitrogen stress disrupts the intestine bacterial community by altering host-community interactions in shrimp., D Hou, H Li, S Wang, S Weng, J He, 2024
Signaling events induced by lipopolysaccharide-activated Toll in response to bacterial infection in shrimp., S Wang, H Li, Q Li, B Yin, S Li, J He, C Li, 2023
An AhR–Caspase Axis Mediated Antiviral Apoptosis in an Arthropod., Q Fu, H Li, S Wang, X Liao, S Chen, B Xiao, R Chen, X Jiang, J He, C Li, 2022
Rap2a is negatively regulated by NF-κB and contributes to growth via wnt pathway in shrimp., S Wang, M He, Q Li, H Li, B Yin, J He, C Li, 2022
Interferon-Induced Protein 6-16 (IFI6-16) from Litopenaeus vannamei Regulate Antiviral Immunity via Apoptosis-Related Genes., K Lǚ, H Li, S Wang, A Li, S Weng, J He, C Li, 2022
TAK1 confers antibacterial protection through mediating the activation of MAPK and NF-κB pathways in shrimp., S Wang, H Li, R Chen, X Jiang, J He, C Li, 2022
Phenylalanine hydroxylase (PAH) plays a positive role during WSSV and Vibrio parahaemolyticus infection in Litopenaeus vannamei., Y Yao, L Shi, W Xiao, S Guo, S Liu, H Li, S Zhang, 2022
MAPKKK15 gene from shrimp litopenaeus vannamei is transcribed in larva development stages and contributes to WSSV pathogenesis., S Wang, H Li, P Zhu, Q Fu, B Yin, Q Li, R Chen, X Jiang, S Weng, J He, 2021
White spot syndrome virus establishes a novel IE1/JNK/c-Jun positive feedback loop to drive replication., S Wang, H Li, S Weng, C Li, J He, 2020
Molecular cloning, expression, promoter analysis and functional characterization of a new Crustin from Litopenaeus vannamei., M Li, C Ma, H Li, J Peng, D Zeng, X Chen, C Li, 2018
MKK4 from Litopenaeus vannamei is a regulator of p38 MAPK kinase and involved in anti-bacterial response., S Wang, B Yin, H Li, B Xiao, K Lǚ, C Feng, J He, C Li, 2018
Shrimp TAB1 interacts with TAK1 and p38 and activates the host innate immune response to bacterial infection., S Wang, M Li, B Yin, H Li, B Xiao, K Lǚ, Z Huang, S Li, J He, C Li, 2017
Identification and functional analysis of a TEP gene from a crustacean reveals its transcriptional regulation mediated by NF-κB and JNK pathways and its broad protective roles., C Li, H Li, B Xiao, Y Chen, S Wang, K Lǚ, B Yin, S Li, J He, 2017
Shrimp with knockdown of LvSOCS2, a negative feedback loop regulator of JAK/STAT pathway in Litopenaeus vannamei, exhibit enhanced resistance against WSSV., S Wang, X Song, Z Zhang, H Li, K Lǚ, B Yin, J He, C Li, 2016
Cloning, identification and functional analysis of a β-catenin homologue from Pacific white shrimp, Litopenaeus vannamei., S Zhang, L Shi, K Lǚ, H Li, S Wang, J He, C Li, 2016
Identification and characterization of transforming growth factor β-activated kinase 1 from Litopenaeus vannamei involved in anti-bacterial host defense., S Wang, H Li, K Lǚ, Z Qian, S Weng, J He, C Li, 2016
Identification and characterization of MKK7 as an upstream activator of JNK in Litopenaeus vannamei., S Wang, Z Qian, H Li, K Lǚ, X Xu, S Weng, J He, C Li, 2016
Activation of Vago by interferon regulatory factor (IRF) suggests an interferon system-like antiviral mechanism in shrimp., C Li, H Li, Y Chen, Y Chen, S Wang, SP Weng, X Xu, J He, 2015
Identification and functional characterization of the TAB2 gene from Litopenaeus vannamei., S Wang, H Li, Z Qian, X Song, Z Zhang, H Zuo, X Xu, S Weng, J He, C Li, 2015
The c-Fos and c-Jun from Litopenaeus vannamei play opposite roles in Vibrio parahaemolyticus and white spot syndrome virus infection., C Li, H Li, S Wang, X Song, Z Zhang, Z Qian, H Zuo, X Xu, S Weng, J He, 2015
Daxx from Pacific white shrimp Litopenaeus vannamei is involved in activation of NF-κB pathway., M Yan, J Tang, Q Liang, G Zhu, H Li, C Li, S Weng, J He, X Xu, 2015
A Janus Kinase in the JAK/STAT signaling pathway from Litopenaeus vannamei is involved in antiviral immune response., X Song, Z Zhang, S Wang, H Li, H Zuo, X Xu, S Weng, J He, C Li, 2015
Identification of a JAK/STAT pathway receptor domeless from Pacific white shrimp Litopenaeus vannamei., M Yan, C Li, Z Su, Q Liang, H Li, S Liang, S Weng, J He, X Xu, 2015
Identification and functional analysis of a Hemolin like protein from Litopenaeus vannamei., H Zuo, H Li, E Wei, Z Su, J Zheng, C Li, Y Chen, S Weng, J He, X Xu, 2015
Identification of a C-type lectin with antiviral and antibacterial activity from pacific white shrimp Litopenaeus vannamei., M Li, C Li, C Ma, H Li, H Zuo, S Weng, X Chen, D Zeng, J He, X Xu, 2014
Pellino protein from pacific white shrimp Litopenaeus vannamei positively regulates NF-κB activation., C Li, J Chai, H Li, H Zuo, S Wang, W Qiu, S Weng, J He, X Xu, 2014
Presence of Tube isoforms in Litopenaeus vannamei suggests various regulatory patterns of signal transduction in invertebrate NF-κB pathway., C Li, Y Chen, S Weng, S Li, H Zuo, X Yu, H Li, J He, X Xu, 2014