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Guang Shi
sg22845482@126.com
Chinese, English
Guangdong
Sun Yat-Sen University
Life Sciences
  • 2007-2012 Doctorate: East China Normal University
  • 2003-2007 Bachelor's: Jilin Normal University
  • Research on epigenetic mechanisms of cell fate regulation
  • Published 19 papers, 11 as first or corresponding author
  • 2022-present - Sun Yat-sen University - Associate Professor
  • 2013-2022 - Sun Yat-sen University - Lecturer
  • 2012-2013 - Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences - Assistant Researcher
  • National Natural Science Foundation Youth Project
  • Guangdong Natural Science Foundation Project
Epigenetic modifications and gene expression regulation
Epigenetic research on embryonic stem cell self-renewal and differentiation
  • Repetitive Sequence Stability in Embryonic Stem Cells, Guang Shi, Qianwen Pang, Zhancheng Lin, Xinyi Zhang, Kaimeng Huang, 2024
  • ILF3 safeguards telomeres from aberrant homologous recombination as a telomeric R-loop reader, Chuanle Wang, Yan Huang, Yue Yang, Ruofei Li, Yingying Li, Hongxin Qiu, Jiali Wu, Guang Shi, Wenbin Ma, Zhou Songyang, 2024
  • Crotonylation of GAPDH regulates human embryonic stem cell endodermal lineage differentiation and metabolic switch, Jingran Zhang, Guang Shi, Junjie Pang, Xing Zhu, Qingcai Feng, Jie Na, Wenbin Ma, Dan Liu, Zhou Songyang, 2023
  • Bend family proteins mark chromatin boundaries and synergistically promote early germ cell differentiation, Guang Shi, Yaofu Bai, Xiya Zhang, Junfeng Su, Junjie Pang, Quanyuan He, Pengguihang Zeng, Junjun Ding, Yuanyan Xiong, Jingran Zhang, Jingwen Wang, Dan Liu, Wenbin Ma, Junjiu Huang, Zhou Songyang, 2022
  • Global molecular features in transcription and chromatin accessibility in human extended pluripotent stem cells, Jingran Zhang, Junjie Pang, Yaofu Bai, Zhancheng Lin, Junjiu Huang, Zhou Songyang, Guang Shi, 2021
  • Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells, Junyu Wu, Chunyan Wu, Fan Xing, Liu Cao, Weijie Zeng, Liping Guo, Ping Li, Yongheng Zhong, Hualian Jiang, Manhui Luo, Guang Shi, Lang Bu, Yanxi Ji, Panpan Hou, Hong Peng, Junjiu Huang, Chunmei Li, Deyin Guo, 2021
  • Wharton's jelly mesenchymal stem cells embedded in PF-127 hydrogel plus sodium ascorbyl phosphate combination promotes diabetic wound healing in type 2 diabetic rat, Yiren Jiao, Xiaolin Chen, Yongxia Niu, Sunxing Huang, Jingwen Wang, Mingxun Luo, Guang Shi, Junjiu Huang, 2021
  • A critical role of telomere chromatin compaction in ALT tumor cell growth, Guang Shi, Yang Hu, Xing Zhu, Yuanling Jiang, Junjie Pang, Chuanle Wang, Wenjun Huang, Yong Zhao, Wenbin Ma, Dan Liu, Junjiu Huang, Zhou Songyang, 2020
  • Ddx56 maintains proliferation of mouse embryonic stem cells via ribosome assembly and interaction with the Oct4/Sox2 complex, Jingwen Wang, Jiahui Liu, Miaoman Ye, Feng Liu, Su Wu, Junjiu Huang, Guang Shi, 2020
  • PF-127 hydrogel plus sodium ascorbyl phosphate improves Wharton’s jelly mesenchymal stem cell-mediated skin wound healing in mice, Qingzha Deng, Sunxing Huang, Jinkun Wen, Yiren Jiao, Xiaohu Su, Guang Shi, Junjiu Huang, 2020
  • Retrotransposons in pluripotent stem cells, Jingwen Wang, Junjiu Huang, Guang Shi, 2020
  • A novel undifferentiated spermatogonia-specific surface protein 1 (USSP1) in neonatal mice, Zhuoheng Lin, Puping Liang, Zhaokai Yao, Yuxi Chen, Xiya Zhang, Rui Huang, Zhen Zhang, Minyan Li, Wenbin Ma, Haiyan Zheng, Shanbo Cao, Guang Shi, Xiaoyang Zhao, Zhou Songyang, Junjiu Huang, 2019
  • Interaction Between Sympk and Oct4 Promotes Mouse Embryonic Stem Cell Proliferation, Jianping Yu, Weisi Lu, Tianyu Ge, Rui Huang, Bohong Chen, Miaoman Ye, Yaofu Bai, Guang Shi, Zhou Songyang, Wenbin Ma, Junjiu Huang, 2019
  • TOE1 acts as a 3’ exonuclease for telomerase RNA and regulates telomere maintenance, Tingting Deng, Yan Huang, Kai Weng, Song Lin, Yujing Li, Guang Shi, Yali Chen, Junjiu Huang, Dan Liu, Wenbin Ma, Zhou Songyang, 2019
  • PCGF5 is required for neural differentiation of embryonic stem cells, Mingze Yao, Xueke Zhou, Jiajian Zhou, Shixin Gong, Gongcheng Hu, Jiao Li, Kaimeng Huang, Ping Lai, Guang Shi, Andrew P. Hutchins, Hao Sun, Huating Wang, Hongjie Yao, 2018
  • SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation, Fang Yu, Guang Shi, Shimeng Cheng, Jiwei Chen, Shwu-Yuan Wu, Zhiqiang Wang, Nansong Xia, Yunhao Zhai, Zhenxing Wang, Yu Peng, Dong Wang, James X. Du, Lujian Liao, Sheng-Zhong Duan, Tieliu Shi, Jinke Cheng, Cheng-Ming Chiang, Jiwen Li, Jiemin Wong, 2018
  • Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX, Yang Hu, Guang Shi, Laichen Zhang, Feng Li, Yuanling Jiang, Shuai Jiang, Wenbin Ma, Yong Zhao, Zhou Songyang, Junjiu Huang, 2016
  • Dynamically reorganized chromatin is the key for the reprogramming of somatic cells to pluripotent cells, Kaimeng Huang, Xiaobai Zhang, Jiejun Shi, Mingze Yao, Jiannan Lin, Jiao Li, He Liu, Huanhuan Li, Guang Shi, Zhibin Wang, Biliang Zhang, Jiekai Chen, Guangjin Pan, Cizhong, Jiang, Duanqing Pei, Hongjie Yao, 2015
  • PHD finger protein 2 (PHF2) represses ribosomal RNA gene transcription by antagonizing PHF finger protein 8 (PHF8) and recruiting methyltransferase SUV39H1, Guang Shi, Meng Wu, Lan Fang, Fang Yu, Shimeng Cheng, Jiwen Li, James X. Du, Jiemin Wong, 2014
  • TPP1 as a versatile player at the ends of chromosomes, Sijie Zhang, Zhenhua Luo, Guang Shi, Dan Liu, Zhou Songyang, Junjiu Huang, 2014
  • The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation, Jihui Qiu, Guang Shi, Yuanhui Jia, Jing Li, Meng Wu, Jiwen Li, Shuo Dong, Jiemin Wong, 2010
  • Deleted in breast cancer 1, a novel androgen receptor (AR) coactivator that promotes AR DNA-binding activity, Junjiang Fu, Jun Jiang, Jiwen Li, Shanshan Wang, Guang Shi, Qin Feng, Eileen White, Jun Qin, Jiemin Wong, 2009
Epigenetics Gene Expression Stem Cells Self-Renewal Differentiation Chromatin Modifications Regulation Embryonic Mechanisms

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