Professor | Juan Chen | Asia Growth Partners

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Name	Juan Chen
Contact Information	chenjuan@cau.edu.cn
Language ability	Chinese, English
Province	Beijing

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Name

Juan Chen

Contact Information

chenjuan@cau.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	China Agricultural University
Faculty	department of nutrition and health
Academic Background & Achievements	2009.09-2015.01 PhD in Animal Physiology: China Agricultural University 2005.09-2009.06 Bachelor in Biological Sciences: Hebei Normal University
Work Experience	2022.10-present - China Agricultural University - Associate Professor 2019.01-2022.09 - Institute of Biophysics, Chinese Academy of Sciences - Associate Researcher 2015.05-2018.12 - Institute of Biophysics, Chinese Academy of Sciences - Assistant Researcher

University/Lab Affiliation and Title

China Agricultural University

Faculty

department of nutrition and health

Academic Background & Achievements

2009.09-2015.01 PhD in Animal Physiology: China Agricultural University
2005.09-2009.06 Bachelor in Biological Sciences: Hebei Normal University

Work Experience

2022.10-present - China Agricultural University - Associate Professor
2019.01-2022.09 - Institute of Biophysics, Chinese Academy of Sciences - Associate Researcher
2015.05-2018.12 - Institute of Biophysics, Chinese Academy of Sciences - Assistant Researcher

Areas of Focus	Pathogenic mechanisms, therapeutic targets, and intervention strategies for immunodeficiency diseases
Publications	PARN maintains RNA stability to regulate insulin maturation and GSIS in pancreatic b cells., Xie XM, Chen XX, Wang CF, Sun LJ, Yu WR, Lv Z, Tian S, Yao XH, Wang FC, Ding DQ, Chen J, Liu JL., 2024 Programmable Chemical Evolution with Natural/non-natural Building Blocks., Liu P#, Jannatul Refeya#, Chen J#, Hou LH#, Gao MJ, Wang PJ, Jin DK, Chen H, Liu R, Wang R, Jia LR, Li YX, Fang B, Sun YN, Zhang YX, Ren FZ, Lin WL., 2024 Temporal-specific single-cell atlas of human type A aortic dissection reveals immune cell dynamics and therapeutic targets., Zhao WT#, Chen J#, Xia Y#, Wei ZX, Wan ST, Guo HY, Hao YL, Jiang WJ, Zhang HJ, Ren FZ, An P, Luo YT, Luo JJ., 2024 Emerging roles of RNA ac4C modification and NAT10 in mammalian development and human diseases., Zhang YG, Lei YM, Dong YB, Chen SW, Sun SY, Zhou FE, Zhao ZW, Chen BN, Wei L, Chen J, Meng ZJ., 2024 The Future landscape and framework of precision nutrition., Han TS, Wei W, Jiang WB, Geng YD, Liu ZJ, Yang RM, Jin CR, Lei YT, Sun XY, Xu JX, Zhou N, Chen J, Sun CH., 2024 Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice., Sun LJ, Lv Z, Chen XX, Ye R, Tian S, Wang CF, Xie XM, Yan L, Yao XH, Shao YJ, Cui S, Chen J, Liu JL., 2024 TSPAN4 influences glioblastoma progression through regulating EGFR stability., Dong YB, Tang XL, Zhao WH, Liu P, Yu WR, Ren JL, Chen Y, Cui YF, Chen J, Liu YS., 2024 ERV: a promising new target for lung adenocarcinoma treatment., Sun SY, Fang B, Wang R, Ren FZ, Chen J., 2023 SRSF1 is crucial for male meiosis through alternative splicing during homologous pairing and synapsis in mice., Sun LJ#, Chen J#, Ye R, Lv Z, Chen XX, Xie XM, Li YH, Wang CF, Lv PB, Yan L, Tian S, Yao XH, Chen C, Cui S, Liu JL., 2023 The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes., Chen J, Cai ZK, Bai MZ, Yu XH, Zhang C, Cao CC, Hu XH, Wang L, Su RB, Wang D, Wang L, Yao YP, Ye R, Hou BD, Yu Y, Yu SY, Li JS, Xue YC., 2018 Emerging roles of non-coding RNAs in epigenetic regulation., Chen J, Xue YC., 2016 LIM-homeodomain transcription factor Isl-1 mediates kisspeptin’s effect on insulin secretion in mice., Chen J, Fu R, Cui Y, Pan JR, Li YS, Zhang XX, Evans Sylvia M, Cui S, Liu JL., 2014 LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice., Chen J, Fu R, Cui Y, Li YS, Pan JR, Liu JL, Luo HS, Yin JD, Li DF, Cui S., 2013 SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis., Zhao HL, Cai ZK, Rao J, Wu D, Ji L, Ye R, Wang D, Chen J, Cao CC, Hu NJ, Shu T, Zhu P, Wang JW, Zhou X, Xue YC., 2024 Complementary Alu sequences mediate enhancer-promoter selectivity., Liang L, Cao CC, Ji L, Cai ZK, Wang D, Ye R, Chen J, Yu XH, Zhou J, Bai ZB, Wang RY, Yang XG, Zhu P, Xue YC., 2023 RIC-seq for global in situ profiling of RNA - RNA spatial interactions., Cai ZK, Cao CC, Ji L, Ye R, Wang D, Xia C, Wang S, Du ZC, Hu NJ, Yu XH, Chen J, Wang L,Yang XG, He SM, Xue YC., 2020 The architecture of the SARS-CoV-2 RNA genome inside virion., Cao CC, Cai ZK, Xiao X, Rao J, Chen J, Hu NJ, Yang MN, Xing XR, Wang YL, Li MM, Zhou B, Wang XX, Wang JW, Xue YC*., 2021

Areas of Focus

Pathogenic mechanisms, therapeutic targets, and intervention strategies for immunodeficiency diseases

Publications

PARN maintains RNA stability to regulate insulin maturation and GSIS in pancreatic b cells., Xie XM, Chen XX, Wang CF, Sun LJ, Yu WR, Lv Z, Tian S, Yao XH, Wang FC, Ding DQ*, Chen J*, Liu JL*., 2024
Programmable Chemical Evolution with Natural/non-natural Building Blocks., Liu P#, Jannatul Refeya#, Chen J#, Hou LH#, Gao MJ, Wang PJ, Jin DK, Chen H, Liu R, Wang R, Jia LR, Li YX, Fang B, Sun YN, Zhang YX, Ren FZ, Lin WL., 2024
Temporal-specific single-cell atlas of human type A aortic dissection reveals immune cell dynamics and therapeutic targets., Zhao WT#, Chen J#, Xia Y#, Wei ZX, Wan ST, Guo HY, Hao YL, Jiang WJ, Zhang HJ, Ren FZ*, An P*, Luo YT*, Luo JJ*., 2024
Emerging roles of RNA ac4C modification and NAT10 in mammalian development and human diseases., Zhang YG, Lei YM, Dong YB, Chen SW, Sun SY, Zhou FE, Zhao ZW, Chen BN, Wei L*, Chen J*, Meng ZJ*., 2024
The Future landscape and framework of precision nutrition., Han TS, Wei W, Jiang WB, Geng YD, Liu ZJ, Yang RM, Jin CR, Lei YT, Sun XY, Xu JX, Zhou N, Chen J*, Sun CH*., 2024
Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice., Sun LJ, Lv Z, Chen XX, Ye R, Tian S, Wang CF, Xie XM, Yan L, Yao XH, Shao YJ, Cui S, Chen J*, Liu JL*., 2024
TSPAN4 influences glioblastoma progression through regulating EGFR stability., Dong YB, Tang XL, Zhao WH, Liu P, Yu WR, Ren JL, Chen Y, Cui YF, Chen J*, Liu YS*., 2024
ERV: a promising new target for lung adenocarcinoma treatment., Sun SY, Fang B, Wang R, Ren FZ, Chen J*., 2023
SRSF1 is crucial for male meiosis through alternative splicing during homologous pairing and synapsis in mice., Sun LJ#, Chen J#, Ye R, Lv Z, Chen XX, Xie XM, Li YH, Wang CF, Lv PB, Yan L, Tian S, Yao XH, Chen C, Cui S, Liu JL*., 2023
The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes., Chen J, Cai ZK, Bai MZ, Yu XH, Zhang C, Cao CC, Hu XH, Wang L, Su RB, Wang D, Wang L, Yao YP, Ye R, Hou BD, Yu Y, Yu SY, Li JS, Xue YC*., 2018
Emerging roles of non-coding RNAs in epigenetic regulation., Chen J, Xue YC*., 2016
LIM-homeodomain transcription factor Isl-1 mediates kisspeptin’s effect on insulin secretion in mice., Chen J, Fu R, Cui Y, Pan JR, Li YS, Zhang XX, Evans Sylvia M, Cui S, Liu JL*., 2014
LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice., Chen J, Fu R, Cui Y, Li YS, Pan JR, Liu JL, Luo HS, Yin JD, Li DF*, Cui S*., 2013
SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis., Zhao HL, Cai ZK, Rao J, Wu D, Ji L, Ye R, Wang D, Chen J, Cao CC, Hu NJ, Shu T, Zhu P, Wang JW, Zhou X, Xue YC., 2024
Complementary Alu sequences mediate enhancer-promoter selectivity., Liang L, Cao CC, Ji L, Cai ZK, Wang D, Ye R, Chen J, Yu XH, Zhou J, Bai ZB, Wang RY, Yang XG, Zhu P, Xue YC*., 2023
RIC-seq for global in situ profiling of RNA - RNA spatial interactions., Cai ZK, Cao CC, Ji L, Ye R, Wang D, Xia C, Wang S, Du ZC, Hu NJ, Yu XH, Chen J, Wang L,Yang XG, He SM, Xue YC*., 2020
The architecture of the SARS-CoV-2 RNA genome inside virion., Cao CC, Cai ZK, Xiao X, Rao J, Chen J, Hu NJ, Yang MN, Xing XR, Wang YL, Li MM, Zhou B, Wang XX, Wang JW*, Xue YC*., 2021

Immunodeficiency Pathogenic Mechanisms Therapeutic Targets Intervention Strategies Disease Immune System Treatment Health Biomedical Research Clinical Applications

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