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Chen She
Biological sciences
National Institute of Biological Sciences，Beijing
Beijing
Language: English, Chinese
Protein
Mass Spectrometry
Biotechnology
Pathogen
Host Interaction
Cell Death
Epigenetics
Circadian Rhythm
Biochemistry
Molecular Biology
Areas of Focus
- Development and application of protein mass spectrometry technology
Work Experience
- 2001-2004 - Protein Mass Spectrometry Technology: University of Texas Southwestern Medical Center at Dallas and MDS Proteomics Inc.
- 2004-present - Established and working at the Proteomics Center, National Institute of Biological Sciences, Beijing
Academic Background & Achievements
- 1995 - Bachelor's in Biochemistry: Wuhan University
- 1998 - Master's in Biophysics: Institute of Biophysics, Chinese Academy of Sciences
- 2000 - Master's in Food Science: Iowa State University
- 2009 - PhD in Biochemistry and Molecular Biology: Beijing Normal University
- 2015 - Selected for the National Hundred, Thousand, and Ten Thousand Talent Project
Publications
- Temporal Proteomic and Phosphoproteomic Analysis of EV-A71-Infected Human Cells, Zhao, Y., Lin, L., Wang, X., He, S., Shi, W., Chen, S., 2022
- A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2alpha-induced corpus luteum regression, Li, D., Chen, J., Guo, J., Li, L., Cai, G., Chen, S., Huang, J., Yang, H., Zhuang, Y., Wang, F., and Wang, X., 2021
- Adaptation of codon usage to tRNA I34 modification controls translation kinetics and proteome landscape, Lyu, X., Yang, Q., Li, L., Dang, Y., Zhou, Z., Chen, S., and Liu, Y., 2020
- Calcium-activated 14-3-3 proteins as a molecular switch in salt stress tolerance, Yang, Z., Wang, C., Xue, Y., Liu, X., Chen, S., Song, C., Yang, Y., and Guo, Y., 2019
- Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation, Liu, J., Li, M., Li, L., Chen, S., and Wang, X., 2018
- N(epsilon)-Fatty acylation of Rho GTPases by a MARTX toxin effector, Zhou, Y., Huang, C., Yin, L., Wan, M., Wang, X., Li, L., Liu, Y., Wang, Z., Fu, P., Zhang, N., Chen, S., Liu, X., Shao, F., and Zhu, Y., 2017
- Stepwise and dynamic assembly of the earliest precursors of small ribosomal subunits in yeast, Zhang, L., Wu, C., Cai, G., Chen, S., and Ye, K., 2016
- A cytosolic heat shock protein 90 and cochaperone CDC37 complex is required for RIP3 activation during necroptosis, Li, D., Xu, T., Cao, Y., Wang, H., Li, L., Chen, S., Wang, X., and Shen, Z., 2015
- O-GlcNAc-modification of SNAP-29 regulates autophagosome maturation, Guo, B., Liang, Q., Li, L., Hu, Z., Wu, F., Zhang, P., Ma, Y., Zhao, B., Kovacs, A.L., Zhang, Z., Feng, D., Chen, S., and Zhang, H., 2014
- Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains, Li, S., Zhang, L., Yao, Q., Li, L., Dong, N., Rong, J., Gao, W., Ding, X., Sun, L., Chen, X., Chen, S., and Shao, F., 2013
- Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase, Sun, L., Wang, H., Wang, Z., He, S., Chen, S., Liao, D., Wang, L., Yan, J., Liu, W., Lei, X., and Wang, X., 2012
- A model for mitotic inheritance of histone lysine methylation, Xu, M., Wang, W., Chen, S., and Zhu, B., 2012
- Cysteine methylation disrupts ubiquitin-chain sensing in NF-kappaB activation, Zhang, L., Ding, X., Cui, J., Xu, H., Chen, J., Gong, Y. N., Hu, L., Zhou, Y., Ge, J., Lu, Q., Liu, L., Chen, S., and Shao, F., 2011
- Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK, Shang, L., Chen, S., Du, F., Li, S., Zhao, L., and Wang, X., 2011
- Partitioning of histone H3-H4 tetramers during DNA replication-dependent chromatin assembly, Xu, M., Long, C., Chen, X., Huang, C., Chen, S., and Zhu, B., 2010
- Glutamine deamidation and dysfunction of ubiquitin/NEDD8 induced by a bacterial effector family, Cui, J., Yao, Q., Li, S., Ding, X., Lu, Q., Mao, H., Liu, L., Zheng, N., Chen, S., and Shao, F., 2010
- Setting the pace of the Neurospora circadian clock by multiple independent FRQ phosphorylation events, Tang, C. T., Li, S., Long, C., Cha, J., Huang, G., Li, L., Chen, S., and Liu, Y., 2009
- Protein kinase A and casein kinases mediate sequential phosphorylation events in the circadian negative feedback loop, Huang, G., Chen, S., Li, S., Cha, J., Long, C., Li, L., He, Q., and Liu, Y., 2007
Awards
- 2015: National Young and Middle-aged Expert with Outstanding Contributions
