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Chen Zhu
Mayo Clinic College of Medicine
University of Science and Technology of China
Anhui
Language: Chinese, English
Immunoregulation
Antibacterial Coatings
Orthopedic Implants
Infections
Clinical Applications
Osteotomy
Joint Replacement
Reconstruction
Osteoarthritis
3D Printing
Areas of Focus
- Immunoregulation and Antibacterial Coatings in Orthopedic Implant Infections
- Adult Bone Joint Osteotomy Correction, Joint Replacement and Reconstruction
- Pathogenesis of Osteoarthritis
- Application of 3D Printing and Modern Communication Big Data Technology in Orthopedics
Work Experience
- 2019-12 to Present: Chief Physician, First Affiliated Hospital, University of Science and Technology of China
- 2017-12 to 2019-11: Associate Chief Physician, First Affiliated Hospital, University of Science and Technology of China
- 2018-12 to 2018-12: Visiting Scholar, Hospital for Special Surgery, USA
- 2014-10 to 2017-11: Associate Chief Physician, Anhui Medical University, Affiliated Provincial Hospital
- 2017-06 to 2017-08: Visiting Scholar, University of Cologne, Germany
- 2008-07 to 2014-09: Attending Physician, Anhui Medical University, Affiliated Provincial Hospital
- 2002-07 to 2008-06: Physician, Anhui Medical University, Affiliated Provincial Hospital
Academic Background & Achievements
- 2011-09 to 2014-06: PhD in Surgery, Shanghai Jiao Tong University
- 2005-09 to 2008-06: Master's in Surgery, Anhui Medical University
- 1997-09 to 2002-06: Bachelor's in Clinical Medicine, Wannan Medical College
Publications
- Bioresponsive nano-antibacterials for H2S-sensitized hyperthermia and immunomodulation against refractory implant-related infections, Su Z, Kong L, Dai Y, Tang J, Mei J, Qian Z, Ma Y, Li Q, Ju S, Wang J, Fan W, Zhu C, 2022
- Biofilm heterogeneity-adaptive photoredox catalysis enables red light-triggered nitric oxide release for combating drug-resistant infections, Cheng J, Gan G, Zheng S, Zhang G, Zhu C, Liu S, Hu J, 2023
- Biofilm Microenvironment-Responsive Self-Assembly Nanoreactors for All-Stage Biofilm Associated Infection through Bacterial Cuproptosis-like Death and Macrophage Re-Rousing, Mei J, Xu D, Wang L, Kong L, Liu Q, Li Q, Zhang X, Su Z, Hu X, Zhu W, Ye M, Wang J, Zhu C, 2023
- Photothermal Nanozyme-Based Microneedle Patch against Refractory Bacterial Biofilm Infection via Iron-Actuated Janus Ion Therapy, Zhu W, Mei J, Zhang X, Zhou J, Xu D, Su Z, Fang S, Wang J, Zhang X, Zhu C, 2022
- Enzymatic bionanocatalysts for combating peri-implant biofilm infections by specific heat-amplified chemodynamic therapy and innate immunomodulation, Su Z, Kong L, Mei J, Li Q, Qian Z, Ma Y, Chen Y, Ju S, Wang J, Jia W, Zhu C, Fan W, 2023
- Biomimetic Metal–Organic Framework Combats Biofilm‐Associated Infections via Hyperthermia‐Enhanced Bacterial Metabolic Interference and Autophagy‐Promoted Adaptive Immunity, Hu X, Ma R, Zhang P, Dong J, Sun J, Wang W, Liu Q, Zhang X, Wang Z, Mei J, Shang X, Zhu W, Su Z, Zhu C, 2024
- Electron Orbital Hybridization‐Enhanced Copper‐Nanocatalysis for Anti‐Infection, Luo Y, Ruan Z, Guo Z, Chen Y, Lin H, Ge M, Zhu C, 2024
- Spatiotemporal On–Off Immunomodulatory Hydrogel Targeting NLRP3 Inflammasome for the Treatment of Biofilm-Infected Diabetic Wounds, Zhou J, Mei J, Liu Q, Xu D, Wang X, Zhang X, Zhu W, Zhu C, Wang J, 2023
- Nanoadjuvant-triggered STING activation evokes systemic immunotherapy for repetitive implant-related infections, Xu D, Hu J, Mei J, Zhou J, Wang Z, Zhang X, Liu Q, Su Z, Zhu W, Liu H, Zhu C, 2024
- Targeted modulation and enhancement of macrophages via sonodynamic therapy-driven cupferroptosis-like stress for implant-associated biofilm infections, Zhang X, Wang Z, Liu Q, Hu X, Mei J, Xu D, Zhou J, Zhang X, Li Q, Chen H, Su Z, Zhu W, Zhu C, 2024
- Honeycomb-inspired ZIF-sealed interface enhances osseointegration via anti-infection and osteoimmunomodulation, Dong J, Zhou W, Hu X, Bai J, Zhang S, Zhang X, Yu L, Yang P, Kong L, Liu M, Shang X, Su Z, Geng D, Zhu C, 2024
- Epigenetic regulatory axis MIR22-TET3-MTRNR2L2 represses fibroblast-like synoviocyte-mediated inflammation in Rheumatoid Arthritis, Fang Y, Huang W, Zhu X, Wang X, Wu X, Wang H, Hong W, Yan S, Zhang L, Deng Y, Wei W, Tu J, Zhu C, 2024
- Biofilm Homeostasis Interference Therapy via 1O2 -Sensitized Hyperthermia and Immune Microenvironment Re-Rousing for Biofilm-Associated Infections Elimination, Li Q, Liu Q, Wang Z, Zhang X, Ma R, Hu X, Mei J, Su Z, Zhu W, Zhu C, 2023
- Acidity-Activatable Nanoparticles with Glucose Oxidase-Enhanced Photoacoustic Imaging and Photothermal Effect, and Macrophage-Related Immunomodulation for Synergistic Treatment of Biofilm Infection, Dai Y, Mei J, Li Z, Kong L, Zhu W, Li Q, Wu K, Huang Y, Shang X, Zhu C, 2022
- Bacteria-based multiplex system eradicates recurrent infections with drug-resistant bacteria via photothermal killing and protective immunity elicitation, Xu Y, Wu Y, Hu Y, Xu M, Liu Y, Ding Y, Chen J, Huang X, Wen L, Li J, Zhu C, 2023
- An injectable photo-cross-linking silk hydrogel system augments diabetic wound healing in orthopaedic surgery through spatiotemporal immunomodulation, Mei J, Zhou J, Kong L, Dai Y, Zhang X, Song W, Zhu C, 2022
Awards
- 2023: First Prize, Anhui Provincial Science and Technology Award, Key Techniques and Applications of Hip Replacement via Direct Anterior Approach in Lateral Position
- 2017: Second Prize, Anhui Provincial Science and Technology Award, Clinical Grading Diagnosis and Treatment of Adult Hip Dysplasia
- 2023: Second Place, National Young Scholar Competition in Orthopedics, Chinese Orthopedic Association
- 2023: First Prize, First Anhui Province Orthopedic Young and Middle-aged Physician Surgical Skills Video Competition (Joint Division)
- 2023: Third Prize, 8th China Innovation Challenge Yangtze River Delta Regional Integration Development Special Competition
- 2022/2023: Nomination Award, Top Ten Scientific and Technological Progress, School of Life Sciences and Medicine, University of Science and Technology of China
- 2022: Nomination Award, Future Technology Innovation Competition, Wuhan Zhongke Advanced Technology Research Institute Co., Ltd.
- 2018: Second Prize, National Orthopedic Physician Annual Meeting and Third Orthopedic Standardized Surgery Video Competition (Joint Group)
- 2017: Second Prize, Young and Middle-aged Excellent Paper, 19th Chinese Orthopedic Academic Conference
- 2017: Advanced Individual in Medical Ethics, Anhui Provincial Education, Science, Culture, Health and Sports Union
- 2015: First Prize, Anhui Province Orthopedic Young and Middle-aged Physician Surgery Standardization Competition
- 2014: First Prize, National Young and Middle-aged Orthopedic Physician Surgery Standardization Competition
