Professor | Xiaoyu Zhu | Asia Growth Partners

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Name	Xiaoyu Zhu
Contact Information	xiaoyuz@ustc.edu.cn
Language ability	Chinese, English
Province	Anhui

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Name

Xiaoyu Zhu

Contact Information

xiaoyuz@ustc.edu.cn

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Mayo Clinic College of Medicine
Academic Background & Achievements	1999/09-2004/07 Bachelor's Degree in Clinical Medicine: Sun Yat-sen University 2004/08-2009/07 Doctorate in Internal Medicine Hematology: Sun Yat-sen University, Supervisor: Yunxian Chen Postdoctoral Supervisor, Deputy Director of the Institute of Hematology and Cell Therapy, USTC Reserve candidate for academic and technical leaders in Anhui Province Recipient of the Outstanding Young Talent Fund of Anhui Province
Work Experience	2009/08-2010/11 - Anhui Provincial Hospital - Resident Physician 2010/12-2013/11 - Anhui Provincial Hospital - Chief Resident, Attending Physician 2013/12-2018/11 - Anhui Provincial Hospital - Associate Chief Physician 2018/12-2019/11 - The First Affiliated Hospital of USTC - Chief Physician 2019/12-present - The First Affiliated Hospital of USTC - Director of Hematology 2020/04-2022/02 - National Natural Science Foundation of China - Project Director
Awards	Anhui Provincial Science and Technology Second Prize (2014): Awarded by Anhui Provincial Government

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Mayo Clinic College of Medicine

Academic Background & Achievements

1999/09-2004/07 Bachelor's Degree in Clinical Medicine: Sun Yat-sen University
2004/08-2009/07 Doctorate in Internal Medicine Hematology: Sun Yat-sen University, Supervisor: Yunxian Chen
Postdoctoral Supervisor, Deputy Director of the Institute of Hematology and Cell Therapy, USTC
Reserve candidate for academic and technical leaders in Anhui Province
Recipient of the Outstanding Young Talent Fund of Anhui Province

Work Experience

2009/08-2010/11 - Anhui Provincial Hospital - Resident Physician
2010/12-2013/11 - Anhui Provincial Hospital - Chief Resident, Attending Physician
2013/12-2018/11 - Anhui Provincial Hospital - Associate Chief Physician
2018/12-2019/11 - The First Affiliated Hospital of USTC - Chief Physician
2019/12-present - The First Affiliated Hospital of USTC - Director of Hematology
2020/04-2022/02 - National Natural Science Foundation of China - Project Director

Awards

Anhui Provincial Science and Technology Second Prize (2014): Awarded by Anhui Provincial Government

Areas of Focus	Biological characteristics and clinical translation of double-negative T (DNT) cells Ex vivo expansion of hematopoietic stem cells and differentiation of megakaryocytes Antitumor mechanisms and clinical applications of γδT cells Hematopoietic and immune reconstitution after hematopoietic stem cell transplantation Research on relapse after hematopoietic stem cell transplantation
Publications	Reconstitution of double-negative T cells after cord blood transplantation and its predictive value for acute graft-versus-host disease., Pan T, Ding P, Huang A, Tang B, Song K, Sun G, Wu Y, Yang S, Chen X, Wang D, Zhu X, 2023 A predictive model combining clinical characteristics and nutritional risk factors for overall survival after umbilical cord blood transplantation., Tu M, Huang A, Ning L, Tang B, Zhang C, Sun G, Wan X, Song K, Yao W, Qiang P, Wu Y, Zhu X, 2023 GARP-mediated active TGF-β1 induces bone marrow NK cell dysfunction in AML patients with early relapse post-allo-HSCT., Wang D, Sun Z, Zhu X, Zhu X, Zheng X, Zhou Y, Lu Y, Yan P, Wang R, Liu H, Jin J, Zhu H, Sun R, Wang Y, Fu B, Tian Z, Wei H, 2022 Injectable bone marrow microniches by co-culture of HSPCs with MSCs in 3D microscaffolds promote hematopoietic reconstitution from acute lethal radiation., Liang H, Ao Y, Li W, Liang K, Tang B, Li J, Wang J, Zhu X, Du Y, 2022 Unrelated cord blood transplantation vs. HLA-matched sibling transplantation for adults with B-cell acute lymphoblastic leukemia in complete remission: superior OS for patients with long-term survival., Sun G, Tang B, Song K, Wu Y, Tu M, Wan X, Yao W, Geng L, Qiang P, Zhu X, 2022 Allogeneic double-negative T cell therapy for relapsed acute myeloid leukemia patients post allogeneic hematopoietic stem cell transplantation: A first-in-human phase I study., Tang B, Lee J, Cheng S, Pan T, Yao W, Wang D, Tu M, Xiang Z, Chu X, Geng L, Qing P, Teng P, Sun G, Liu H, Wang J, D.Schimmer A, Yang L, Sun Z, Zhang L, Zhu X, 2022 Chimeric Antigen Receptor T Cell Therapy followed by Unrelated Cord Blood Transplantation for the Treatment of Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia in Children and Young Adults: Superior Survival but Relatively High Post-Transplantation Relapse., Sun G, Tang B, Wan X, Yao W, Song K, Tu M, Geng L, Qiang P, Wu Y, Zhu L, Wu Y, Liu H, Zhu X, Sun Z, 2022 Poor survival and prediction of prolonged isolated thrombocytopenia post umbilical cord blood transplantation in patients with hematological malignancies., Wu Y, Zhang Z, Tu M, Pan T, Ding P, Tang B, Wan X, Yao W, Song K, Sun G, Geng L, Qiang P, Liu H, Zhu X, Sun Z, 2022 The clinical influence of preformed nonspecific anti-HLA antibodies on single-unit umbilical cord blood transplantation in patients with haematological malignancies., Wu Y, Tang B, Song K, Sun G, Tu M, Wan X, Yao W, Qiang P, Pan T, Ding P, Zhu X, 2022 Recombinant human thrombopoietin promotes platelet engraftment after umbilical cord blood transplantation., Tang B, Huang L, Liu H, Cheng S, Song K, Zhang X, Yao W, Ning L, Wan X, Sun G, Wu Y, Cheng J, Long Q, Sun Z, Zhu X, 2020

Areas of Focus

Biological characteristics and clinical translation of double-negative T (DNT) cells
Ex vivo expansion of hematopoietic stem cells and differentiation of megakaryocytes
Antitumor mechanisms and clinical applications of γδT cells
Hematopoietic and immune reconstitution after hematopoietic stem cell transplantation
Research on relapse after hematopoietic stem cell transplantation

Publications

Reconstitution of double-negative T cells after cord blood transplantation and its predictive value for acute graft-versus-host disease., Pan T, Ding P, Huang A, Tang B, Song K, Sun G, Wu Y, Yang S, Chen X, Wang D, Zhu X, 2023
A predictive model combining clinical characteristics and nutritional risk factors for overall survival after umbilical cord blood transplantation., Tu M, Huang A, Ning L, Tang B, Zhang C, Sun G, Wan X, Song K, Yao W, Qiang P, Wu Y, Zhu X, 2023
GARP-mediated active TGF-β1 induces bone marrow NK cell dysfunction in AML patients with early relapse post-allo-HSCT., Wang D, Sun Z, Zhu X, Zhu X, Zheng X, Zhou Y, Lu Y, Yan P, Wang R, Liu H, Jin J, Zhu H, Sun R, Wang Y, Fu B, Tian Z, Wei H, 2022
Injectable bone marrow microniches by co-culture of HSPCs with MSCs in 3D microscaffolds promote hematopoietic reconstitution from acute lethal radiation., Liang H, Ao Y, Li W, Liang K, Tang B, Li J, Wang J, Zhu X, Du Y, 2022
Unrelated cord blood transplantation vs. HLA-matched sibling transplantation for adults with B-cell acute lymphoblastic leukemia in complete remission: superior OS for patients with long-term survival., Sun G, Tang B, Song K, Wu Y, Tu M, Wan X, Yao W, Geng L, Qiang P, Zhu X, 2022
Allogeneic double-negative T cell therapy for relapsed acute myeloid leukemia patients post allogeneic hematopoietic stem cell transplantation: A first-in-human phase I study., Tang B, Lee J, Cheng S, Pan T, Yao W, Wang D, Tu M, Xiang Z, Chu X, Geng L, Qing P, Teng P, Sun G, Liu H, Wang J, D.Schimmer A, Yang L, Sun Z, Zhang L, Zhu X, 2022
Chimeric Antigen Receptor T Cell Therapy followed by Unrelated Cord Blood Transplantation for the Treatment of Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia in Children and Young Adults: Superior Survival but Relatively High Post-Transplantation Relapse., Sun G, Tang B, Wan X, Yao W, Song K, Tu M, Geng L, Qiang P, Wu Y, Zhu L, Wu Y, Liu H, Zhu X, Sun Z, 2022
Poor survival and prediction of prolonged isolated thrombocytopenia post umbilical cord blood transplantation in patients with hematological malignancies., Wu Y, Zhang Z, Tu M, Pan T, Ding P, Tang B, Wan X, Yao W, Song K, Sun G, Geng L, Qiang P, Liu H, Zhu X, Sun Z, 2022
The clinical influence of preformed nonspecific anti-HLA antibodies on single-unit umbilical cord blood transplantation in patients with haematological malignancies., Wu Y, Tang B, Song K, Sun G, Tu M, Wan X, Yao W, Qiang P, Pan T, Ding P, Zhu X, 2022
Recombinant human thrombopoietin promotes platelet engraftment after umbilical cord blood transplantation., Tang B, Huang L, Liu H, Cheng S, Song K, Zhang X, Yao W, Ning L, Wan X, Sun G, Wu Y, Cheng J, Long Q, Sun Z, Zhu X, 2020

Dnt Cells Clinical Translation Hematopoietic Stem Cells Megakaryocytes Γδt Cells Antitumor Immune Reconstitution Stem Cell Transplantation Relapse Biological Characteristics

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