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You Shang
Mayo Clinic College of Medicine
University of Science and Technology of China
Anhui
Language: Chinese, English
Sepsis
Immune Pathology
Molecular Mechanisms
Intervention Strategies
Acute Respiratory Distress Syndrome
Inflammation
Immunity
Organ Damage
Clinical Research
Multicenter Studies
Areas of Focus
- Molecular mechanisms and intervention strategies of immune pathology in sepsis
- Molecular immune mechanisms and interventions in acute respiratory distress syndrome
Work Experience
- 2001/09-2006/07 - Huazhong University of Science and Technology - Doctoral Student
Academic Background & Achievements
- 2001/09-2006/07 Doctorate: Huazhong University of Science and Technology
- Published over 100 academic papers in journals like Lancet Respiratory Medicine, Critical Care, Immunity
- H-index of 35, highest single paper impact factor of 102, cited over 4700 times
- Selected as Elsevier's Highly Cited Chinese Researcher in 2020, 2021, and 2022
- Organized 6 clinical diagnosis and treatment expert consensus
- Led 5 multicenter clinical studies
Publications
- Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study, Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, Wu Y, Zhang L, Yu Z, Fang M, Yu T, Wang Y, Pan S, Zou X, Yuan S, Shang Y, 2020
- NLRC3 expression in macrophage impairs glycolysis and host immune defense by modulating the NF-κB-NFAT5 complex during septic immunosuppression, Xu J, Gao C, He Y, Fang X, Sun D, Peng Z, Xiao H, Sun M, Zhang P, Zhou T, Yang X, Yu Y, Li R, Zou X, Shu H, Qiu Y, Zhou X, Yuan S, Yao S, Shang Y, 2023
- Mechanical activation of the ion channel Piezo1 mediates mechanical ventilation-exacerbated ARDS-associated pulmonary fibrosis, Fang X, Li M, Wang Y, Zhang P, Sun M, Xu JX, Yang Y, He YJ, Yu Y, Li R, Zhou T, Reng L, Sun D, Shu H, Yuan S, Xu J, Shang Y, 2022
- Plasma Proteomics Identify Biomarkers and Pathogenesis of COVID-19, Shu T, Ning W, Wu D, Xu J, Han Q, Huang M, Zou X, Yang Q, Yuan Y, Bie Y, Pan S, Mu J, Han Y, Yang X, Zhou H, Li R, Ren Y, Chen X, Yao S, Qiu Y, Zhang DY, Xue Y, Shang Y, Zhou X, 2020
- Plasma metabolome and cytokine profile reveal glycylproline modulating antibody fading in convalescent COVID-19 patients, Yang Z, Wu D, Lu S, Qiu Y, Hua Z, Tan F, Zhang C, Zhang L, Zhang DY, Zhou X, Cai Z, Shang Y, Lin SH, 2022
- MDSCs in sepsis-induced immunosuppression and its potential therapeutic targets, Zhang W, Fang X, Gao C, Song C, He Y, Zhou T, Yang X, Shang Y, Xu J, 2022
- Effects of airway pressure release ventilation on lung physiology assessed by electrical impedance tomography in patients with early moderate-to-severe ARDS, Li R, Wu Y, Zhang H, Wang A, Zhao X, Yuan S, Yang L, Zou X, Shang Y, Zhao Z, 2023
- Remimazolam besylate versus propofol for long-term sedation during invasive mechanical ventilation: a pilot study, Tang Y, Yang X, Yu Y, Shu H, Yuan Y, Liu H, Zou X, Yuan S, Shang Y, 2022
Awards
- National Advanced Individual in Fighting COVID-19
