Professor | You Shang | Asia Growth Partners

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Name	You Shang
Contact Information	you_shanghust@163.com
Language ability	Chinese, English
Province	Anhui

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Name

You Shang

Contact Information

you_shanghust@163.com

Language ability

Chinese, English

Province

Anhui

University/Lab Affiliation and Title	University of Science and Technology of China
Faculty	Mayo Clinic College of Medicine
Academic Background & Achievements	2001/09-2006/07 Doctorate: Huazhong University of Science and Technology Published over 100 academic papers in journals like Lancet Respiratory Medicine, Critical Care, Immunity H-index of 35, highest single paper impact factor of 102, cited over 4700 times Selected as Elsevier's Highly Cited Chinese Researcher in 2020, 2021, and 2022 Organized 6 clinical diagnosis and treatment expert consensus Led 5 multicenter clinical studies
Work Experience	2001/09-2006/07 - Huazhong University of Science and Technology - Doctoral Student
Awards	National Advanced Individual in Fighting COVID-19

University/Lab Affiliation and Title

University of Science and Technology of China

Faculty

Mayo Clinic College of Medicine

Academic Background & Achievements

2001/09-2006/07 Doctorate: Huazhong University of Science and Technology
Published over 100 academic papers in journals like Lancet Respiratory Medicine, Critical Care, Immunity
H-index of 35, highest single paper impact factor of 102, cited over 4700 times
Selected as Elsevier's Highly Cited Chinese Researcher in 2020, 2021, and 2022
Organized 6 clinical diagnosis and treatment expert consensus
Led 5 multicenter clinical studies

Work Experience

2001/09-2006/07 - Huazhong University of Science and Technology - Doctoral Student

Awards

National Advanced Individual in Fighting COVID-19

Areas of Focus	Molecular mechanisms and intervention strategies of immune pathology in sepsis Molecular immune mechanisms and interventions in acute respiratory distress syndrome
Publications	Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study, Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, Wu Y, Zhang L, Yu Z, Fang M, Yu T, Wang Y, Pan S, Zou X, Yuan S, Shang Y, 2020 NLRC3 expression in macrophage impairs glycolysis and host immune defense by modulating the NF-κB-NFAT5 complex during septic immunosuppression, Xu J, Gao C, He Y, Fang X, Sun D, Peng Z, Xiao H, Sun M, Zhang P, Zhou T, Yang X, Yu Y, Li R, Zou X, Shu H, Qiu Y, Zhou X, Yuan S, Yao S, Shang Y, 2023 Mechanical activation of the ion channel Piezo1 mediates mechanical ventilation-exacerbated ARDS-associated pulmonary fibrosis, Fang X, Li M, Wang Y, Zhang P, Sun M, Xu JX, Yang Y, He YJ, Yu Y, Li R, Zhou T, Reng L, Sun D, Shu H, Yuan S, Xu J, Shang Y, 2022 Plasma Proteomics Identify Biomarkers and Pathogenesis of COVID-19, Shu T, Ning W, Wu D, Xu J, Han Q, Huang M, Zou X, Yang Q, Yuan Y, Bie Y, Pan S, Mu J, Han Y, Yang X, Zhou H, Li R, Ren Y, Chen X, Yao S, Qiu Y, Zhang DY, Xue Y, Shang Y, Zhou X, 2020 Plasma metabolome and cytokine profile reveal glycylproline modulating antibody fading in convalescent COVID-19 patients, Yang Z, Wu D, Lu S, Qiu Y, Hua Z, Tan F, Zhang C, Zhang L, Zhang DY, Zhou X, Cai Z, Shang Y, Lin SH, 2022 MDSCs in sepsis-induced immunosuppression and its potential therapeutic targets, Zhang W, Fang X, Gao C, Song C, He Y, Zhou T, Yang X, Shang Y, Xu J, 2022 Effects of airway pressure release ventilation on lung physiology assessed by electrical impedance tomography in patients with early moderate-to-severe ARDS, Li R, Wu Y, Zhang H, Wang A, Zhao X, Yuan S, Yang L, Zou X, Shang Y, Zhao Z, 2023 Remimazolam besylate versus propofol for long-term sedation during invasive mechanical ventilation: a pilot study, Tang Y, Yang X, Yu Y, Shu H, Yuan Y, Liu H, Zou X, Yuan S, Shang Y, 2022

Areas of Focus

Molecular mechanisms and intervention strategies of immune pathology in sepsis
Molecular immune mechanisms and interventions in acute respiratory distress syndrome

Publications

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study, Yang X, Yu Y, Xu J, Shu H, Xia J, Liu H, Wu Y, Zhang L, Yu Z, Fang M, Yu T, Wang Y, Pan S, Zou X, Yuan S, Shang Y, 2020
NLRC3 expression in macrophage impairs glycolysis and host immune defense by modulating the NF-κB-NFAT5 complex during septic immunosuppression, Xu J, Gao C, He Y, Fang X, Sun D, Peng Z, Xiao H, Sun M, Zhang P, Zhou T, Yang X, Yu Y, Li R, Zou X, Shu H, Qiu Y, Zhou X, Yuan S, Yao S, Shang Y, 2023
Mechanical activation of the ion channel Piezo1 mediates mechanical ventilation-exacerbated ARDS-associated pulmonary fibrosis, Fang X, Li M, Wang Y, Zhang P, Sun M, Xu JX, Yang Y, He YJ, Yu Y, Li R, Zhou T, Reng L, Sun D, Shu H, Yuan S, Xu J, Shang Y, 2022
Plasma Proteomics Identify Biomarkers and Pathogenesis of COVID-19, Shu T, Ning W, Wu D, Xu J, Han Q, Huang M, Zou X, Yang Q, Yuan Y, Bie Y, Pan S, Mu J, Han Y, Yang X, Zhou H, Li R, Ren Y, Chen X, Yao S, Qiu Y, Zhang DY, Xue Y, Shang Y, Zhou X, 2020
Plasma metabolome and cytokine profile reveal glycylproline modulating antibody fading in convalescent COVID-19 patients, Yang Z, Wu D, Lu S, Qiu Y, Hua Z, Tan F, Zhang C, Zhang L, Zhang DY, Zhou X, Cai Z, Shang Y, Lin SH, 2022
MDSCs in sepsis-induced immunosuppression and its potential therapeutic targets, Zhang W, Fang X, Gao C, Song C, He Y, Zhou T, Yang X, Shang Y, Xu J, 2022
Effects of airway pressure release ventilation on lung physiology assessed by electrical impedance tomography in patients with early moderate-to-severe ARDS, Li R, Wu Y, Zhang H, Wang A, Zhao X, Yuan S, Yang L, Zou X, Shang Y, Zhao Z, 2023
Remimazolam besylate versus propofol for long-term sedation during invasive mechanical ventilation: a pilot study, Tang Y, Yang X, Yu Y, Shu H, Yuan Y, Liu H, Zou X, Yuan S, Shang Y, 2022

Sepsis Immune Pathology Molecular Mechanisms Intervention Strategies Acute Respiratory Distress Syndrome Inflammation Immunity Organ Damage Clinical Research Multicenter Studies

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