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Mingming Zhao
Basic Medical Sciences
Chongqing Medical University
Chongqing
Language: English, Chinese, Japanese
Stem Cells
Differentiation
Regenerative Medicine
Ipscs
Clinical Application
Biotechnology
Organ Regeneration
Disease Modeling
Cell Fate
Tissue Repair
Areas of Focus
- Stem cell differentiation and regenerative medicine
Work Experience
- 2014-2022 - Kyoto University iPS Cell Research Institute - Researcher
Academic Background & Achievements
- Ph.D. in Medicine: Kyoto University
- Led 3 national research projects in Japan
- Published multiple papers in renowned journals
Publications
- Establishing stable and highly osteogenic hiPSC-derived MSCs for 3D-printed bone graft through microenvironment modulation by CHIR99021-treated osteocytes, Guo Q, Chen J, Bu Q, Zhang J, Ruan M, Chen X, Zhao M, Tu X, Zhao C, 2024
- Heparan sulfate chain-conjugated laminin-E8 fragments advance paraxial mesodermal differentiation followed by high myogenic induction from hiPSCs, Zhao M, Taniguchi Y, Shimono C, Jonouchi T, Cheng Y, Shimizu Y, Nalbandian M, Yamamoto T, Nakagawa M, Sekiguchi K, Sakurai H, 2024
- Single-cell RNA-seq reveals heterogeneity in hiPSC-derived muscle progenitors and E2F family as a key regulator of proliferation, Nalbandian M, Zhao M, Kato H, Jonouchi T, Nakajima-Koyama M, Yamamoto T, Sakurai H, 2022
- Collagen-VI supplementation by cell transplantation improves muscle regeneration in Ullrich congenital muscular dystrophy model mice, Takenaka-Ninagawa N, Kima J, Zhao M, Sato M, Jonouchi T, Goto M, Yoshioka C, Ikeda R, Harada A, Sato T, Ikeya M, Uezumi A, Nakatani M, Noguchi S, Sakurai H, 2021
- Characterization of hiPSC-Derived Muscle Progenitors Reveals Distinctive Markers for Myogenic Cell Purification Toward Cell Therapy, Nalbandian M, Zhao M, Sasaki-Honda M, Jonouchi T, Lucena-Cacace A, Mizusawa T, Yasuda M, Yoshida Y, Hotta A, Sakurai H, 2021
- Induced Fetal Human Muscle Stem Cells with High Therapeutic Potential in a Mouse Muscular Dystrophy Model, Zhao M, Tazumi A, Takayama S, Takenaka-Ninagawa M, Nalbandian M, Nagai M, Nakamura Y, Nakasa M, Watanabe A, Ikeya M, Hotta A, Ito Y, Sato T, Sakurai H, 2020
- In Vitro Evaluation of Exon Skipping in Disease-Specific iPSC-Derived Myocytes, Zhao M, Shoji E, Sakurai H, 2018
- Fat Mass Reduction with Adipocyte Hypertrophy and Insulin Resistance in Heterozygous PPARγ Mutant Rats, Gumbilai V, Ebihara K, Aizawa-Abe M, Ebihara C, Zhao M, Yamamoto Y, Mashimo T, Hosoda K, Serikawa T, Nakao K, 2016
- Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice, Cai X, Fang C, Hayashi S, Hao S, Zhao M, Tsutsui H, Nishiguchi S, Sheng J, 2016
- Seipin is necessary for normal brain development and spermatogenesis in addition to adipogenesis, Ebihara C, Ebihara K, Aizawa-Abe M, Mashimo T, Tomita T, Zhao M, Gumbilai V, Kusakabe T, Yamamoto Y, Aotani D, Yamamoto-Kataoka S, Sakai T, Hosoda K, Serikawa T, Nakao K, 2015
- Azilsartan treatment improves insulin sensitivity in obese spontaneously hypertensive Koletsky rats, Zhao M, Li Y, Wang J, Ebihara K, Rong X, Hosoda K, Tomita T, Nakao K, 2011
- Angiotensin II type 1 receptor-independent beneficial effects of telmisartan on dietary-induced obesity, insulin resistance and fatty liver in mice, Rong X, Li Y, Ebihara K, Zhao M, Naowaboot J, Kusakabe T, Kuwahara K, Murray M, Nakao K, 2010
Awards
- 2016: Excellent Poster Award, The 39th MBSJ
- 2017: Best Oral Presentation Award, CiRA Retreat
- 2019: Best Oral Presentation Award, CiRA Retreat
- 2021: CiRA Encouragement Award
