Upload Avatar (500 x 500)
Zhang Zheng
Basic Medical Sciences
Chongqing Medical University
Chongqing
Language: Chinese, English
Kidney Injury
Molecular Mechanisms
Diabetic Nephropathy
Inflammation
Mesangial Cells
Nf-Kb Pathway
Lncrna
Cerna Network
Renal Fibrosis
Calcium Signaling
Areas of Focus
- Molecular mechanisms of kidney injury
Work Experience
- 2003-present - Chongqing Medical University, School of Basic Medicine, Department of Cell Biology and Genetics - Lecturer/Associate Professor/Professor
- 2014-2015 - Harvard Medical School - Visiting Scholar
Academic Background & Achievements
- 1995-2000 Bachelor in Clinical Medicine: Southwest Medical University
- 2000-2003 Master in Human Anatomy and Embryology: Chongqing Medical University
- 2006-2009 PhD in Biomedical Engineering: Chongqing Medical University
- Published over 70 academic articles, with 2 highly cited papers in the top 0.1% globally in clinical medicine
Publications
- LincRNA-Gm4419 knockdown ameliorates NF-κB/NLRP3 inflammasome-mediated inflammation in diabetic nephropathy., Yi H, Peng R, Zhang LY, Sun Y, Peng HM, Liu HD, Yu LJ, Li AL, Zhang YJ, Jiang WH, Zhang Z, 2017
- Long non-coding RNA Rpph1 promotes the inflammation and mesangial cell proliferation via interacting with Gal-3 in diabetic nephropathy., Zhang PY, Sun Y, Peng R, Chen WY, Fu X, Zhang LY, Peng HM, Zhang Z, 2019
- The topological key lncRNA H2k2 from ceRNA network promotes mesangial cell proliferation via miR-449a/b/Trim11/Mek signaling pathway in diabetic nephropathy., Chen WY, Peng R, Sun Y, Liu HD, Zhang LY, Peng HM, Zhang Z, 2019
- CircUBXN7 promotes macrophage infiltration and renal fibrosis associated with the IGF2BP2-dependent SP1 mRNA stability in diabetic kidney disease., Lin ZY, Lv D, Liao XH, Peng R, Liu HD, Wu TH, Wu KQ, Sun Y, Zhang Z, 2023
- Sfrp2 promotes renal dysfunction of diabetic kidney disease via modulating Fzd5-induced cytosolic calcium ion concentration and CaMKII/Mek/Erk pathway in mesangial cells., Lv D, Lin Z, Liao X, Peng R, Liu H, Wu T, Wu K, Sun Y, Zhang Z, 2024
Awards
- 2022: Chongqing Excellent Undergraduate Thesis Supervisor for research on Rack1-mediated NF-kB pathway in diabetic nephropathy
- 2023: Chongqing Medical University Excellent Master's Thesis Supervisor for research on LncMCS in diabetic nephropathy
