Professor | Wei Xu | Asia Growth Partners

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Name	Wei Xu
Contact Information	wxu29@cqmu.edu.cn
Language ability	English, Chinese
Province	Chongqing

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Name

Wei Xu

Contact Information

wxu29@cqmu.edu.cn

Language ability

English, Chinese

Province

Chongqing

University/Lab Affiliation and Title	Chongqing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2009.09-2013.07 Bachelor of Science in Pharmacy: Peking University 2010.09-2013.07 Bachelor of Economics (Double Degree): Peking University 2013.09-2015.07 Master of Science in Chemical Biology: Peking University 2015.08-2021.04 PhD in Pharmacology and Molecular Sciences: Johns Hopkins University Published as first author in Nature, Acta Pharmaceutica Sinica B, Cell Reports
Work Experience	2015.08-2021.04 - Johns Hopkins University - PhD Research 2021.04-2022.01 - Johns Hopkins University - Postdoctoral Research 2022.03-2024.02 - TianKeYa Biotechnology Co., Ltd. - Research and Development Staff 2024.02-present - Chongqing Medical University - Distinguished Professor

University/Lab Affiliation and Title

Chongqing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2009.09-2013.07 Bachelor of Science in Pharmacy: Peking University
2010.09-2013.07 Bachelor of Economics (Double Degree): Peking University
2013.09-2015.07 Master of Science in Chemical Biology: Peking University
2015.08-2021.04 PhD in Pharmacology and Molecular Sciences: Johns Hopkins University
Published as first author in Nature, Acta Pharmaceutica Sinica B, Cell Reports

Work Experience

2015.08-2021.04 - Johns Hopkins University - PhD Research
2021.04-2022.01 - Johns Hopkins University - Postdoctoral Research
2022.03-2024.02 - TianKeYa Biotechnology Co., Ltd. - Research and Development Staff
2024.02-present - Chongqing Medical University - Distinguished Professor

Areas of Focus	Molecular mechanisms of metabolic regulation of immune cell function and differentiation
Publications	GOT1 constrains TH17 cell and promotes Treg cell differentiation., Wei Xu, Chirag H. Patel, Jesse Alt, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Richard L. Blosser, Ada J. Tam, Jonathan D. Powell, 2023 GOT1 regulates CD8+ effector and memory T cell generation., Wei Xu, Chirag H. Patel, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Rachel Helms, Jiayu Wen, Jonathan D. Powell, 2023 Peeking under the hood of naive T cells., Wei Xu, Jonathan D. Powell, 2018 Factors to consider in developing individual pharmaceutical product quality risk profiles useful to government procurement agencies., Wei Xu, Boehm Garth, Qiang Zheng, 2016 Synergism between thioredoxin reductase inhibitor ethaselen and sodium selenite in inhibiting proliferation and inducing death of human non-small cell lung cancer cells., Xiaoqing Zheng, Wei Xu, Ruoxuan Sun, Hanwei Yin, Chaoran Dong, Huihui Zeng, 2017 A tunable brake for HECT ubiquitin ligases., Zan Chen, Hanjie Jiang, Wei Xu, Xiaoguang Li, Daniel R. Dempsey, Xiangbin Zhang, Peter Devreotes, Cynthia Wolberger, L. Mario Amzel, Sandra B. Gabelli, Philip A. Cole, 2017 mTORC2 regulates CD8+ effector and memory T cell differentiation through serum and glucocorticoid kinase 1., Chirag H. Patel, Emily B. Heikamp, Wei Xu, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Ada J. Tam, Richard L. Blosser, Jonathan D. Powell, 2022 Modulation of p300/CBP acetylation of nucleosomes by bromodomain ligand I-CBP112., Beth E Zucconi, Birgit Luef, Wei Xu, Ryan A. Henry, Ilana M. Nodelman, Gregory D. Bowman, Andrew J. Andrews, Philip A. Cole, 2016 Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells., Min-Hee Oh, Im-Hong Sun, Liang Zhao, Robert D. Leone, Im-Meng Sun, Wei Xu, Samuel L. Collins, Ada J. Tam, Richard L. Blosser, Chirag H. Patel, Judson M. Englert, Matthew L. Arwood, Jiayu Wen, Yee Chan-Li, Lukáš Tenora, Pavel Majer, Rana Rais, Barbara S. Slusher, Maureen R. Horton, Jonathan D. Powell, 2020 mTOR complex 1 signaling regulates the generation and function of central and effector Foxp3+ regulatory T cells., Im-Hong Sun, Min-Hee Oh, Liang Zhao, Chirag H. Patel, Matthew L. Arwood, Wei Xu, Ada J. Tam, Richard L. Blosser, Jiayu Wen, Jonathan D. Powell, 2018

Areas of Focus

Molecular mechanisms of metabolic regulation of immune cell function and differentiation

Publications

GOT1 constrains TH17 cell and promotes Treg cell differentiation., Wei Xu, Chirag H. Patel, Jesse Alt, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Richard L. Blosser, Ada J. Tam, Jonathan D. Powell, 2023
GOT1 regulates CD8+ effector and memory T cell generation., Wei Xu, Chirag H. Patel, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Rachel Helms, Jiayu Wen, Jonathan D. Powell, 2023
Peeking under the hood of naive T cells., Wei Xu, Jonathan D. Powell, 2018
Factors to consider in developing individual pharmaceutical product quality risk profiles useful to government procurement agencies., Wei Xu, Boehm Garth, Qiang Zheng, 2016
Synergism between thioredoxin reductase inhibitor ethaselen and sodium selenite in inhibiting proliferation and inducing death of human non-small cell lung cancer cells., Xiaoqing Zheng, Wei Xu, Ruoxuan Sun, Hanwei Yin, Chaoran Dong, Huihui Zeng, 2017
A tunable brake for HECT ubiquitin ligases., Zan Chen, Hanjie Jiang, Wei Xu, Xiaoguang Li, Daniel R. Dempsey, Xiangbin Zhang, Peter Devreotes, Cynthia Wolberger, L. Mario Amzel, Sandra B. Gabelli, Philip A. Cole, 2017
mTORC2 regulates CD8+ effector and memory T cell differentiation through serum and glucocorticoid kinase 1., Chirag H. Patel, Emily B. Heikamp, Wei Xu, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Ada J. Tam, Richard L. Blosser, Jonathan D. Powell, 2022
Modulation of p300/CBP acetylation of nucleosomes by bromodomain ligand I-CBP112., Beth E Zucconi, Birgit Luef, Wei Xu, Ryan A. Henry, Ilana M. Nodelman, Gregory D. Bowman, Andrew J. Andrews, Philip A. Cole, 2016
Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells., Min-Hee Oh, Im-Hong Sun, Liang Zhao, Robert D. Leone, Im-Meng Sun, Wei Xu, Samuel L. Collins, Ada J. Tam, Richard L. Blosser, Chirag H. Patel, Judson M. Englert, Matthew L. Arwood, Jiayu Wen, Yee Chan-Li, Lukáš Tenora, Pavel Majer, Rana Rais, Barbara S. Slusher, Maureen R. Horton, Jonathan D. Powell, 2020
mTOR complex 1 signaling regulates the generation and function of central and effector Foxp3+ regulatory T cells., Im-Hong Sun, Min-Hee Oh, Liang Zhao, Chirag H. Patel, Matthew L. Arwood, Wei Xu, Ada J. Tam, Richard L. Blosser, Jiayu Wen, Jonathan D. Powell, 2018

Metabolism Immune Cells Function Differentiation Molecular Mechanisms Regulation T Cells Metabolic Pathways Immune Response Cellular Processes

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