Areas of Focus
- Antibody Engineering and B Cell Function
Work Experience
- 2019-present - Chongqing Medical University - Associate Researcher in Immunology
Academic Background & Achievements
- 2010-2014 Bachelor: Harbin Medical University, Basic Medicine
- 2014-2015 Master: Harbin Medical University, Basic Medicine
- 2015-2018 Doctorate: Harbin Medical University, Pharmacology
- 2019-2021 Postdoctoral: Chongqing Medical University, Basic Medicine
Publications
- Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants, Li T., Han X., Gu C., Guo H., Zhang H., Wang Y., Hu C., Wang K., Liu F., Luo F., Zhang Y., Hu J., Wang W., Li S., Hao Y., Shen M., Huang J., Long Y., Song S., Wu R., Mu S., Chen Q., Gao F., Wang J., Long S., Li L., Wu Y., Gao Y., Xu W., Cai X., Qu D., Zhang Z., Zhang H., Li N., Gao Q., Zhang G., He C., Wang W., Ji X., Tang N., Yuan Z., Xie Y., Yang H., Zhang B., Huang A., Jin A., 2021
- A potent neutralizing antibody provides protection against SARS-CoV-2 Omicron and Delta variants via nasal delivery, Zhang X., Zhang H., Li T., Chen S., Luo F., Zhou J., Zheng P., Song S., Wu Y., Jin T., Tang N., Jin A., Yang C., Cheng G., Gong R., Chiu S., Huang A., 2022
- Structures of Omicron spike complexes and implications for neutralizing antibody development, Guo H., Gao Y., Li T., Li T., Lu Y., Zheng L., Liu Y., Yang T., Luo F., Song S., Wang W., Yang X., Nguyen H.C., Zhang H., Huang A., Jin A., Yang H., Rao Z., Ji X., 2022
- A non-RBM targeted RBD specific antibody neutralizes SARS-CoV-2 inducing S1 shedding, Long Y., Song S., Luo F., Han X., Hu C., Wang Y., Li S., Wang W., Zhang H., Zhang B., Li T., Jin A., 2021
- Silencing of METTL3 attenuates cardiac fibrosis induced by myocardial infarction via inhibiting the activation of cardiac fibroblasts, Li, T., Y. Zhuang, W. Yang, Y. Xie, W. Shang, S. Su, X. Dong, J. Wu, W. Jiang, Y. Zhou, Y. Li, X. Zhou, M. Zhang, Y. Lu, Z. Pan, 2021
- Involvement of lncR-30245 in Myocardial Infarction–Induced Cardiac Fibrosis Through Peroxisome Proliferator-Activated Receptor-γ–Mediated Connective Tissue Growth Factor Signalling Pathway, Zhuang, Y., T. Li, Y. Zhuang, Z. Li, W. Yang, Q. Huang, D. Li, H. Wu, G. Zhang, T. Yang, L. Zhan, Z. Pan, Y. Lu, 2019
- LncRNA-H19 Drives Cardiomyocyte Senescence by Targeting miR-19a/socs1/p53 Axis, Zhuang, Y., T. Li, H. Xiao, J. Wu, S. Su, X. Dong, X. Hu, Q. Hua, J. Liu, W. Shang, J. Ju, F. Sun, Z. Pan, Y. Lu, M. Zhang, 2021
- Ablation of interleukin-17 alleviated cardiac interstitial fibrosis and improved cardiac function via inhibiting long non-coding RNA-AK081284 in diabetic mice, Zhang, Y., Y.-Y. Zhang, T.-T. Li, J. Wang, Y. Jiang, Y. Zhao, X.-X. Jin, G.-L. Xue, Y. Yang, X.-F. Zhang, Y.-Y. Sun, Z.-R. Zhang, X. Gao, Z.-M. Du, Y.-J. Lu, B.-F. Yang, Z.-W. Pan, 2018
Awards
- 2021: Chongqing Public Institution Staff Award
- 2022: Chongqing Public Institution Staff Award
