Professor | Shipeng Shao | Asia Growth Partners

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Name	Shipeng Shao
Contact Information	ssp@cqmu.edu.cn
Language ability	Chinese, English
Province	Chongqing

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Name

Shipeng Shao

Contact Information

ssp@cqmu.edu.cn

Language ability

Chinese, English

Province

Chongqing

University/Lab Affiliation and Title	Chongqing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2009-2013 Bachelor's in Bioengineering: Sichuan University 2013-2018 Doctorate in Biophysics: Peking University Chongqing Young Talent
Work Experience	2018-2020 - Peking University Biomedical Frontier Innovation Center - Postdoctoral Researcher 2021-2022 - Beijing Anzhen Hospital Heart and Lung Research Institute - Assistant Researcher 2022-present - Chongqing Medical University, School of Basic Medicine, Department of Biochemistry and Molecular Biology - Professor
Awards	2013: Sichuan Province Outstanding Graduate 2018: Beijing Outstanding Graduate

University/Lab Affiliation and Title

Chongqing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2009-2013 Bachelor's in Bioengineering: Sichuan University
2013-2018 Doctorate in Biophysics: Peking University
Chongqing Young Talent

Work Experience

2018-2020 - Peking University Biomedical Frontier Innovation Center - Postdoctoral Researcher
2021-2022 - Beijing Anzhen Hospital Heart and Lung Research Institute - Assistant Researcher
2022-present - Chongqing Medical University, School of Basic Medicine, Department of Biochemistry and Molecular Biology - Professor

Awards

2013: Sichuan Province Outstanding Graduate
2018: Beijing Outstanding Graduate

Areas of Focus	Pathogenic Mechanisms of Developmental Disorders Protein Liquid-Liquid Phase Separation in Chromatin Structure and Gene Expression Regulation
Publications	Reversible phase separation of HSF1 is required for an acute transcriptional response during heat shock., Hongchen Zhang, Shipeng Shao, Yong Zeng, Xiaotian Wang, Yizhi Qin, Qiunan Ren, Shengqi Xiang, Yuxin Wang, Junyu Xiao, Yujie Sun, 2022 Long-term dual-color tracking of genomic loci by modified sgRNAs of the CRISPR/Cas9 system., Shipeng Shao, Weiwei Zhang, Huan Hu, Boxin Xue, Jinshan Qin, Chaoying Sun, Yuao Sun, Wensheng Wei, Yujie Sun, 2016 Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells., Lei Chang, Mengfan Li, Shipeng Shao, Boxin Xue, Yingping Hou, Ruifeng Li, Cheng Li, Yujie Sun, 2020 Multiplexed sgRNA expression allows versatile single nonrepetitive DNA labeling and endogenous gene regulation., Shipeng Shao, Lei Chang, Yuao Sun, Yingping Hou, Xiaoying Fan, Yujie Sun, 2017 TagBiFC technique allows long-term single-molecule tracking of protein-protein interactions in living cells., Shipeng Shao, Hongchen Zhang, Yong Zeng, Yongliang Li, Chaoying Sun, Yujie Sun, 2021 Intranucleus single-molecule imaging in living cells., Shipeng Shao, Boxin Xue, Yujie Sun, 2018 Illuminating the structure and dynamics of chromatin by fluorescence labeling., Shipeng Shao, Lei Chang, Yingping Hou, Yujie Sun, 2017 Characterization of liquid-liquid phase separation using super-resolution and single-molecule imaging., Hongchen Zhang, Shipeng Shao, Yujie Sun, 2022 LIMD1 phase separation contributes to cellular mechanics and durotaxis by regulating focal adhesion dynamics in response to force., Yuan Wang, Chunlei Zhang, Wenzhong Yang, Shipeng Shao, Xinmin Xu, Yujie Sun, Pilong Li, Ling Liang, Congying Wu, 2021 Nuclear actin regulates inducible transcription by enhancing RNA polymerase II clustering., Mian Wei, Xiaoying Fan, Miao Ding, Ruifeng Li, Shipeng Shao, Yingping Hou, Shaoshuai Meng, Fuchou Tang, Cheng Li, Yujie Sun, 2020 MapZ Forms a Stable Ring Structure That Acts as a Nanotrack for FtsZ Treadmilling in Streptococcus Mutans., Yongliang Li, Shipeng Shao, Xiao Xu, Xiaodong Su, Yujie Sun, Shicheng Wei, 2018 AgoFISH: cost-effective in situ labelling of genomic loci based on DNA-guided dTtAgo protein., Lei Chang, Gang Sheng, Yiwen Zhang, Shipeng Shao, Yanli Wang, Yujie Sun, 2020 PN-ImTLSM facilitates high-throughput low background single-molecule localization microscopy deep in the cell., Xue Boxin, Zhou Caiwei, Qin Yizhi, Li Yongzheng, Sun Yuao, Chang Lei, Shao Shipeng, Li Yongliang, Zhang Mengling, Sun Chaoying, He Renxi, Peter Su Qian, Sun Yujie, 2022

Areas of Focus

Pathogenic Mechanisms of Developmental Disorders
Protein Liquid-Liquid Phase Separation in Chromatin Structure and Gene Expression Regulation

Publications

Reversible phase separation of HSF1 is required for an acute transcriptional response during heat shock., Hongchen Zhang, Shipeng Shao, Yong Zeng, Xiaotian Wang, Yizhi Qin, Qiunan Ren, Shengqi Xiang, Yuxin Wang, Junyu Xiao, Yujie Sun, 2022
Long-term dual-color tracking of genomic loci by modified sgRNAs of the CRISPR/Cas9 system., Shipeng Shao, Weiwei Zhang, Huan Hu, Boxin Xue, Jinshan Qin, Chaoying Sun, Yuao Sun, Wensheng Wei, Yujie Sun, 2016
Nuclear peripheral chromatin-lamin B1 interaction is required for global integrity of chromatin architecture and dynamics in human cells., Lei Chang, Mengfan Li, Shipeng Shao, Boxin Xue, Yingping Hou, Ruifeng Li, Cheng Li, Yujie Sun, 2020
Multiplexed sgRNA expression allows versatile single nonrepetitive DNA labeling and endogenous gene regulation., Shipeng Shao, Lei Chang, Yuao Sun, Yingping Hou, Xiaoying Fan, Yujie Sun, 2017
TagBiFC technique allows long-term single-molecule tracking of protein-protein interactions in living cells., Shipeng Shao, Hongchen Zhang, Yong Zeng, Yongliang Li, Chaoying Sun, Yujie Sun, 2021
Intranucleus single-molecule imaging in living cells., Shipeng Shao, Boxin Xue, Yujie Sun, 2018
Illuminating the structure and dynamics of chromatin by fluorescence labeling., Shipeng Shao, Lei Chang, Yingping Hou, Yujie Sun, 2017
Characterization of liquid-liquid phase separation using super-resolution and single-molecule imaging., Hongchen Zhang, Shipeng Shao, Yujie Sun, 2022
LIMD1 phase separation contributes to cellular mechanics and durotaxis by regulating focal adhesion dynamics in response to force., Yuan Wang, Chunlei Zhang, Wenzhong Yang, Shipeng Shao, Xinmin Xu, Yujie Sun, Pilong Li, Ling Liang, Congying Wu, 2021
Nuclear actin regulates inducible transcription by enhancing RNA polymerase II clustering., Mian Wei, Xiaoying Fan, Miao Ding, Ruifeng Li, Shipeng Shao, Yingping Hou, Shaoshuai Meng, Fuchou Tang, Cheng Li, Yujie Sun, 2020
MapZ Forms a Stable Ring Structure That Acts as a Nanotrack for FtsZ Treadmilling in Streptococcus Mutans., Yongliang Li, Shipeng Shao, Xiao Xu, Xiaodong Su, Yujie Sun, Shicheng Wei, 2018
AgoFISH: cost-effective in situ labelling of genomic loci based on DNA-guided dTtAgo protein., Lei Chang, Gang Sheng, Yiwen Zhang, Shipeng Shao, Yanli Wang, Yujie Sun, 2020
PN-ImTLSM facilitates high-throughput low background single-molecule localization microscopy deep in the cell., Xue Boxin, Zhou Caiwei, Qin Yizhi, Li Yongzheng, Sun Yuao, Chang Lei, Shao Shipeng, Li Yongliang, Zhang Mengling, Sun Chaoying, He Renxi, Peter Su Qian, Sun Yujie, 2022

Developmental Disorders Pathogenic Mechanisms Protein Phase Separation Chromatin Structure Gene Expression Transcription Factors Chromatin Binding Proteins Molecular Mechanisms Biochemistry Molecular Biology

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