Professor | Yang Shengyong | Asia Growth Partners

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Name	Yang Shengyong
Contact Information	yangshengyong@cqmu.edu.cn
Language ability	English, Chinese
Province	Chongqing

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Name

Yang Shengyong

Contact Information

yangshengyong@cqmu.edu.cn

Language ability

English, Chinese

Province

Chongqing

University/Lab Affiliation and Title	Chongqing Medical University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1987-1992 Bachelor: Ningxia Medical University, Clinical Medicine 1998-2001 Master: Lanzhou University, Biochemistry and Molecular Biology 2004-2008 Doctorate: Peking University Health Science Center, Biochemistry and Molecular Biology Hosted a National Natural Science Foundation project and a provincial-level research project
Work Experience	2009-2011 - University of Pittsburgh School of Medicine - Postdoctoral Researcher 2012-2014 - University of Pittsburgh Medical Center - Postdoctoral Researcher 2014-present - Chongqing Medical University, School of Basic Medicine, Department of Biochemistry and Molecular Biology - Professor

University/Lab Affiliation and Title

Chongqing Medical University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1987-1992 Bachelor: Ningxia Medical University, Clinical Medicine
1998-2001 Master: Lanzhou University, Biochemistry and Molecular Biology
2004-2008 Doctorate: Peking University Health Science Center, Biochemistry and Molecular Biology
Hosted a National Natural Science Foundation project and a provincial-level research project

Work Experience

2009-2011 - University of Pittsburgh School of Medicine - Postdoctoral Researcher
2012-2014 - University of Pittsburgh Medical Center - Postdoctoral Researcher
2014-present - Chongqing Medical University, School of Basic Medicine, Department of Biochemistry and Molecular Biology - Professor

Areas of Focus	RNA editing and cancer Anticancer drugs
Publications	An integrative pan-cancer bioinformatics analysis of MSRB1 and its association with tumor immune microenvironment, prognosis, and immunotherapy., Jiang S, Yang S, Gao Z, Yin C, Zhang M, Wu Q, Li Y, 2024 RNA Editing Enzyme ADAR1 Regulates METTL3 in an Editing Dependent Manner to Promote Breast Cancer Progression via METTL3/ARHGAP5/YTHDF1 Axis., Li Y, Wang NX, Yin C, Jiang SS, Li JC, Yang SY, 2022 MsrB1 Promotes Proliferation and Invasion of Colorectal Cancer Cells via GSK-3β/β-catenin Signaling Axis., Chen XY, Yang SY, Ruan XJ, Ding HY, Wang NX, Liu F, Li JC, Li Y, 2021 8-Chloro-Adenosine Inhibits Proliferation of MDA-MB-231 and SK-BR-3 Breast Cancer Cells by Regulating ADAR1/p53 Signaling Pathway., Ding HY, Yang WY, Zhang LH, Li L, Xie F, Li HY, Chen XY, Tu Z, Li Y, Chen Y, Yang SY, 2020 DNA Damage-Response Pathway Heterogeneity of Human Lung Cancer A549 and H1299 Cells Determines Sensitivity to 8-Chloro-Adenosine., Yang S-Y, Li Y, An G-S, Ni J-H, Jia H-T, Li S-Y, 2018 Adenosine Deaminase Acting on RNA 1 Limits RIG-I RNA Detection and Suppresses IFN Production Responding to Viral and Endogenous RNAs., Yang S, Deng P, Zhu Z, Zhu J, Wang G, Zhang L, Chen AF, Wang T, Sarkar SN, Billiar TR, Wang Q, 2014 Foxo1 mediates insulin-like growth factor 1 (IGF1)/insulin regulation of osteocalcin expression by antagonizing Runx2 in osteoblasts., Yang S, Xu H, Yu S, Cao H, Fan J, Ge C, Fransceschi RT, Dong HH, Xiao G, 2011 Inhibition of CHK1 kinase by Gö6976 converts 8-chloro-adenosine-induced G2/M arrest into S arrest in human myelocytic leukemia K562 cells., Jia XZ, Yang SY, Zhou J, Li SY, Ni JH, An GS, Jia HT, 2009 Inhibition of topoisomerase II by 8-chloro-adenosine triphosphate induces DNA double-stranded breaks in 8-chloro-adenosine-exposed human myelocytic leukemia K562 cells., Yang SY, Jia XZ, Feng LY, Li SY, An GS, Ni JH, Jia HT, 2009

Areas of Focus

RNA editing and cancer
Anticancer drugs

Publications

An integrative pan-cancer bioinformatics analysis of MSRB1 and its association with tumor immune microenvironment, prognosis, and immunotherapy., Jiang S, Yang S, Gao Z, Yin C, Zhang M, Wu Q, Li Y, 2024
RNA Editing Enzyme ADAR1 Regulates METTL3 in an Editing Dependent Manner to Promote Breast Cancer Progression via METTL3/ARHGAP5/YTHDF1 Axis., Li Y, Wang NX, Yin C, Jiang SS, Li JC, Yang SY, 2022
MsrB1 Promotes Proliferation and Invasion of Colorectal Cancer Cells via GSK-3β/β-catenin Signaling Axis., Chen XY, Yang SY, Ruan XJ, Ding HY, Wang NX, Liu F, Li JC, Li Y, 2021
8-Chloro-Adenosine Inhibits Proliferation of MDA-MB-231 and SK-BR-3 Breast Cancer Cells by Regulating ADAR1/p53 Signaling Pathway., Ding HY, Yang WY, Zhang LH, Li L, Xie F, Li HY, Chen XY, Tu Z, Li Y, Chen Y, Yang SY, 2020
DNA Damage-Response Pathway Heterogeneity of Human Lung Cancer A549 and H1299 Cells Determines Sensitivity to 8-Chloro-Adenosine., Yang S-Y, Li Y, An G-S, Ni J-H, Jia H-T, Li S-Y, 2018
Adenosine Deaminase Acting on RNA 1 Limits RIG-I RNA Detection and Suppresses IFN Production Responding to Viral and Endogenous RNAs., Yang S, Deng P, Zhu Z, Zhu J, Wang G, Zhang L, Chen AF, Wang T, Sarkar SN, Billiar TR, Wang Q, 2014
Foxo1 mediates insulin-like growth factor 1 (IGF1)/insulin regulation of osteocalcin expression by antagonizing Runx2 in osteoblasts., Yang S, Xu H, Yu S, Cao H, Fan J, Ge C, Fransceschi RT, Dong HH, Xiao G, 2011
Inhibition of CHK1 kinase by Gö6976 converts 8-chloro-adenosine-induced G2/M arrest into S arrest in human myelocytic leukemia K562 cells., Jia XZ, Yang SY, Zhou J, Li SY, Ni JH, An GS, Jia HT, 2009
Inhibition of topoisomerase II by 8-chloro-adenosine triphosphate induces DNA double-stranded breaks in 8-chloro-adenosine-exposed human myelocytic leukemia K562 cells., Yang SY, Jia XZ, Feng LY, Li SY, An GS, Ni JH, Jia HT, 2009

Rna Editing Cancer Tumor Oncology Genetics Biochemistry Molecular Biology Drug Development Therapeutics Biomedical Research

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