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Li Wen
Basic Medical Sciences
Chongqing Medical University
Chongqing
Language: English, Chinese
Genomic Stability
Tumorigenesis
Nuclear Skeleton
Protein Identification
Tumor Function
Molecular Targets
Gene Regulation
Lipid Metabolism
Cytoskeleton Remodeling
Tumor Invasion
Areas of Focus
- Mechanisms of genomic stability maintenance in tumorigenesis
- Identification and function of nuclear skeleton proteins in tumors
Work Experience
- 2019-2022 - Shenzhen University - Postdoctoral Researcher
- 2022-present - Chongqing Medical University - Associate Professor
Academic Background & Achievements
- 2009-2013 Bachelor: Huazhong University of Science and Technology
- 2013-2019 Doctorate: Peking University
- Published over 10 SCI papers
- Led multiple national, provincial, and university-level research projects
Publications
- Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment., Li Wen, Li Feifei, Zhang Xia, Lin Hui-Kuan, Xu Chuan, 2021
- The nucleoskeleton protein IFFO1 immobilizes broken DNA and suppresses chromosome translocation during tumorigenesis., Li Wen, Bai Xiuzhen, Li Jun, Zhao Yichao, Liu Jingyan, Zhao Huayu, Liu Lan, Ding Miao, Wang Qingsong, Shi Fang-Yuan, Hou Mei, Ji Jianguo, Gao Ge, Guo Rong, Sun Yujie, Liu Yingfang, Xu Dongyi, 2019
- Revealing potential lipid biomarkers in clear cell renal cell carcinoma using targeted quantitative lipidomics., Li Wen, Wang Xiaobin, Zhang Xianbin, Gong Peng, Ding Degang, Wang Ning, Wang Zhifeng, 2021
- Topoisomerase 3β is the major topoisomerase for mRNAs and linked to neurodevelopment and mental dysfunction., Ahmad Muzammil, Shen Weiping, Li Wen, Xue Yutong, Zou Sige, Xu Dongyi, Wang Weidong, 2017
- A dual-activity topoisomerase complex regulates mRNA translation and turnover., Su Shuaikun, Xue Yutong, Sharov Alexei, Zhang Yongqing, Lee Seung Kyu, Martindale Jennifer L, Li Wen, Ku Wai Lim, Zhao Keji, De Supriyo, Shen Weiping, Sen Payel, Gorospe Myriam, Xu Dongyi, Wang Weidong, 2022
Awards
- 2021: Winner of the First National Postdoctoral Innovation and Entrepreneurship Competition
