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Chao Wang
Institute of Neuroscience and Brain Disease Research
Chongqing Medical University
Chongqing
Language: English, Chinese
Alzheimer'S Disease
Pathogenesis
Prevention
Lipid Metabolism
Apoe4
Genetic Factors
Disease Progression
Neurodegeneration
Synaptic Phagocytosis
Cerebrovascular Protection
Areas of Focus
- Research on the pathogenesis and prevention of Alzheimer's disease
Work Experience
- 2024-03 to present - Chongqing Medical University - Executive Deputy Director of the Key Laboratory of Major Brain Diseases and Aging
- 2024-01 to present - Chongqing Key Laboratory of Brain Development and Cognition - Deputy Director
- 2023-11 to present - Chongqing Medical University - Vice Dean of the Institute of Brain Science and Brain Diseases
- 2022-03 to present - Chongqing Medical University - Professor at the Institute of Brain Science and Brain Diseases
- 2017-01 to 2022-01 - Washington University in St. Louis - Postdoctoral Researcher in the Department of Neurology
Academic Background & Achievements
- 2012-10 to 2016-09 PhD in Medical Biochemistry and Biophysics: Umeå University
- 2010-09 to 2012-06 Master's in Molecular Biology: Umeå University
- 2004-09 to 2008-06 Bachelor's in Bioengineering: Hubei University
Publications
- Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia., Wang, Chao; Xiong, Monica; Gratuze, Maud; et al., 2021
- Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy., Xiong, Monica*; Wang, Chao*; Gratuze, Maud*; et al., 2023
- Selective reduction of astrocyte apoE3 and apoE4 strongly reduces Aβ accumulation and plaque-related pathology in a mouse model of amyloidosis., Mahan, Thomas E*; Wang, Chao*; Bao, Xin; et al., 2022
- Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model., Huynh, Tien-Phat V*; Wang, Chao*; Tran, Ainsley C; et al., 2019
- S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer's Disease., Wang, Chao*; Iashchishyn, Igor A*; Pansieri, Jonathan; et al., 2018
- The role of pro-inflammatory S100A9 in Alzheimer's disease amyloid-neuroinflammatory cascade., Wang, Chao*; Klechikov, Alexey G*; Gharibyan, Anna L*; et al., 2014
- Proinflammatory and amyloidogenic S100A9 induced by traumatic brain injury in mouse model., Wang, Chao*; Iashchishyn, Igor A*; Kara, John; et al., 2019
Awards
- 2023: Chongqing Bayu Scholar - Young Scholar
