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Manran Liu
Laboratory Medicine
Chongqing Medical University
Chongqing
Language: Chinese, English
Breast Cancer
Metastasis
Drug Resistance
Biomarkers
Tumor Microenvironment
Cancer Stem Cells
Tumor Metabolism
Signal Transduction
Hypoxia
Lncrna
Areas of Focus
- Breast tumor metastasis, drug resistance, and biomarkers
- Tumor microenvironment and cancer cell interaction
Work Experience
- 1991.06-1999.08 Assistant Researcher, Lecturer: Institute of Oceanology, Chinese Academy of Sciences, Qingdao University Medical College
- 2003.02-2008.11 Postdoctoral Researcher, Assistant Researcher: Georgetown University, Thomas Jefferson University
- 2009.06-present Professor: Chongqing Medical University, School of Laboratory Medicine
Academic Background & Achievements
- 1984.09-1988.06 Bachelor in Biology: Hunan Normal University
- 1988.09-1991.06 Master in Ecology: Shandong University
- 1999.09-2002.06 PhD in Tumor Molecular Biology: Peking University
Publications
- Cancer-associated fibroblasts facilitate premetastatic niche formation through lncRNA SNHG5-mediated vascular permeability and angiogenesis in breast cancer., Huan Zeng, Yixuan Hou, Haojun Luo, Yan Sun, Xueying Wan, Taixian Yuan, Yongcan Liu, Rui Wang, Rui Tang, Shaojie Cheng, Xinyue Zhou, Ming Xu, and Manran Liu, 2022
- A novel long noncoding RNA lncROPM-mediated phospholipid metabolism governs breast cancer stem cell properties., Shuiqing Liu, Yan Sun, Yixuan Hou, Liping Yang, Xueying Wan, Yilu Qin, Yongcan Liu, Rui Wang, Pengpeng Zhu, Yong Teng, Manran Liu, 2021
- Hypoxia-stimulated ATM Activation Regulates Autophagy-associated Exosomes Release from Cancer-Associated Fibroblasts to Promote Cancer Cell Invasion., Lei Xi, Meixi Peng, Shuiqing Liu, Yongcan Liu, Xueying Wan, Yixuan Hou, Yilu Qin, Liping Yang, Shanchun Chen, Huan Zeng, Yong Teng, Xiaojiang Cui, Manran Liu, 2021
- A novel long non-coding RNA lnc030 maintains breast cancer stem cell stemness by stabilizing SQLE mRNA and increasing cholesterol synthesis., Yilu Qin, Yixuan Hou, Shuiqing Liu, Pengpeng Zhu, Xueying Wan, Maojia Zhao, Meixi Peng, Huan Zeng, Qiao Li, Ting Jin, Xiaojiang Cui, Manran Liu, 2021
- Mirtronic miR-4646-5p promotes gastric cancer metastasis by regulating ABHD16A and metabolite lysophosphatidylserines., Liping Yang, Yixuan Hou, Yan-e Du, Qiao Li, Fanlin Zhou, Yu Li, Huan Zeng, Ting Jin, Xueying Wan, Shengdong Guan, Rui Wang, Manran Liu, 2021
- SLC6A8-mediated intracellular creatine accumulation enhances hypoxic breast cancer cell survival via ameliorating oxidative stress., Qiao Li, Manran Liu, Yan Sun, Ting Jin, Pengpeng Zhu, Xueying Wan, Yixuan Hou, Gang Tu, 2021
- FOSL2 promotes VEGF-independent angiogenesis by regulating Wnt5a in breast cancer-associated fibroblasts., Xueying Wan, Shengdong Guan, Yixuan Hou, Yilu Qin, Huan Zeng, Liping Yang, Yina Qiao, Shuiqing Liu, Qiao Li, Ting Jin, Yuxiang Qiu, Manran Liu, 2021
- Effects of differential distributed-JUP on the malignancy of gastric cancer., Yanlin Chen, Liping Yang, Yilu Qin, Shuiqing Liu, Yina Qiao, Xueying Wan, Huan Zeng, Xiaoli Tang, Manran Liu, Yixuan Hou, 2021
- MiR-205/YAP1 in Activated Fibroblasts of Breast Tumor Promotes VEGF-independent Angiogenesis through STAT3 Signaling., Yan-e Du, Gang Tu, Guanglun Yang, Genyou Li, Dan Yang, Lei Lang, Lei Xi, Kexin Sun, Yanlin Chen, Kunxian Shu, Huadong Liao, Manran Liu, Yixuan Hou, 2017
- Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodeling., Xi Tang, Yixuan Hou, Guanglun Yang, Xing Wang, Shifu Tang, Yan-e Du, Li Yang, Tenghua Yu, Hailong Zhang, Mingli Zhou, Siyang Wen, Liyun Xu, Manran Liu, 2016
Awards
- 2019: Chongqing Science and Technology Award, Natural Science Award, Second Prize
- 2018: Chongqing Association for Science and Technology 'Outstanding Academic Paper in Natural Science' Award
- 2014-2020: Chongqing Medical University Outstanding Graduate Supervisor
- 2015-2022: Chongqing Medical University Outstanding Scientific Paper Award
