Areas of Focus
- Immune mechanisms of pathogen-host cell interactions
- Tumor immune mechanisms and signaling pathways
- Molecular mechanisms of bacterial pathogenicity and molecular diagnostics development
Work Experience
- 1997-present - Faculty Member: Chongqing Medical University
- 2011-present - Research and Graduate Management: Key Laboratory of Clinical Laboratory Diagnostics, Ministry of Education
Academic Background & Achievements
- 1997 - Bachelor's degree in Clinical Laboratory Science: Chongqing Medical University
- 2006 - Master's degree in Clinical Laboratory Diagnostics: Chongqing Medical University
- 2012 - Doctorate in Clinical Laboratory Diagnostics: Chongqing Medical University
- 2011-2012 - Visiting Scholar: Texas A&M University Health Science Center, Houston
Publications
- Protective Regulatory T Cell Immune Response Induced by Intranasal Immunization With the Live-Attenuated Pneumococcal Vaccine SPY1 via the Transforming Growth Factor-beta1-Smad2/3 Pathway, Liao H, Peng X, Gan L, Feng J, Gao Y, Yang S, Hu X, Zhang L, Yin Y, Wang H, Xu X, 2018
- spd1672, a novel in vivo-induced gene, affects inflammatory response in a murine model of Streptococcus pneumoniae infection, Gan L, Zhang X, Xu X, Xu W, Lu C, Cui J, Wang H, 2018
- Nontypeable Haemophilus influenzae DNA stimulates type I interferon expression via STING signaling pathway, ChangLu, XuemeiZhang, ChenyuMa, WenchunXu, LinglingGan, JinCui, YibingYin, HongWang, 2018
- DnaJ (hsp40) of Streptococcus pneumoniae is involved in bacterial virulence and elicits a strong natural immune reaction via PI3K/JNK, Jin Cui, Chenyu Ma, Guo Ye, Yong Shi, Wenchun Xu, Liang Zhong, Jian Wang, Yibing Yin, Xuemei Zhang, Hong Wang, 2017
- GHIP in Streptococcus pneumoniae is involved in antibacterial resistance and elicits a strong innate immune response through TLR2 and JNK/p38MAPK, Dong J, Wang J, He Y, Li C, Zhou A, Cui J, Xu W, Zhong L, Yin Y, Zhang X, Wang H, 2014
- Mucosal immunization with recombinant fusion protein DnaJ-ΔA146Ply enhances cross-protective immunity against Streptococcus pneumoniae infection in mice via IL-17A, Liu Y, Wang H, Zhang S, Zeng L, Xu X, Wu K, Wang W, Yin N, Song Z, Zhang X, Yin Y, 2014
- 肺炎链球菌dnaJ基因缺陷菌株的构建及毒力变化的初步研究, 崔瑾,张群,董杰,尹一兵,王虹, 2011
- Apoptosis induced by pneumolysin in human endothelial cells involves mitogen-activated protein kinase phosphorylation, Aie Zhou, Hong Wang, Kai Lan, Xuemei Zhang, Wenchun Xu, Yibing Yin, Dairong Li, Jun Yuan, Yujuan He, 2012
- SP0454, a putative threonine dehydratase, is required for pneumococcal virulence in mice, Yan W, Wang H, Xu W, Wu K, Yao R, Xu X, Dong J, Zhang Y, Zhong W, Zhang X, 2012
Awards
- 2008: Excellent Instructor, 6th 'Challenge Cup' China University Student Entrepreneurship Competition, Chongqing
- 2011: Third Prize, Education Award Fund, Chongqing Municipal Committee of the China Democratic League
- 2012: Second Prize, Chongqing Science and Technology Award (Natural Science), 'Pathogenic Mechanism and Prevention of Streptococcus pneumoniae'
- 2016: Guided student to win 'Roche Diagnostics China Medical and Life Education Research Fund'
- 2017: Guided student to win Third Prize, '13th National Clinical Microbiology Academic Conference Excellent Paper'
- 2018: Guided student to win First Prize, '14th National Laboratory Medicine Academic Conference Excellent Paper'
- 2019: Guided student to win 'Advanced Individual of Young Volunteers' at Chongqing Medical University