Upload Avatar (500 x 500)
Ling Zhang
Laboratory Medicine
Chongqing Medical University
Chongqing
Language: Chinese, English
Aml
Molecular Mechanisms
Npm1 Mutation
Precision Medicine
Leukemia
Diagnosis
Treatment
Research
Oncology
Hematology
Areas of Focus
- Molecular mechanisms of acute myeloid leukemia (AML)
- Precision diagnosis and treatment strategies for NPM1-mutated AML
Work Experience
- 1993.07-1998.10 Assistant Lecturer, Department of Medical Laboratory Science, Chongqing Medical University
- 1998.11-2003.10 Lecturer, Department of Medical Laboratory Science, Chongqing Medical University
- 2003.11-2010.10 Associate Professor, Department of Medical Laboratory Science, Chongqing Medical University
- 2010.11-present Professor, School of Laboratory Medicine, Chongqing Medical University
- 2011.09-2012.09 Visiting Scholar, Department of Molecular & Cellular Oncology, MD Anderson Cancer Center, USA
Academic Background & Achievements
- 1988.09-1993.07 Bachelor of Medical Laboratory Science: Chongqing Medical University
- 1995.09-1998.07 Master of Clinical Laboratory Diagnostics: Chongqing Medical University
- 2001.09-2004.07 Doctorate in Clinical Laboratory Diagnostics: Chongqing Medical University
- Visiting Scholar at MD Anderson Cancer Center, USA
Publications
- Targeted activation of GPER enhances the efficacy of venetoclax by boosting leukemic pyroptosis and CD8+ T cell immune function in acute myeloid leukemia., Jun Ren, Yonghong Tao, Meixi Peng, Qiaoling Xiao, Yipei Jing, Junpeng Huang, Jing Yang, Can Lin, Minghui Sun, Li Lei, Zesong Yang, Zailin Yang, Ling Zhang, 2022
- Tumour-derived small extracellular vesicles suppress CD8+ T cell immune function by inhibiting SLC6A8-mediated creatine import in NPM1-mutated acute myeloid leukaemia., Meixi Peng, Jun Ren, Yipei Jing, Xueke Jiang, Qiaoling Xiao, Junpeng Huang, Yonghong Tao, Li Lei, Xin Wang, Zailin Yang, Zesong Yang, Qian Zhan, Can Lin, Guoxiang Jin, Xian Zhang, Ling Zhang, 2021
- Mutant NPM1-regulated lncRNA HOTAIRM1 promotes leukemia cell autophagy and proliferation by targeting EGR1 and ULK3., Yipei Jing, Xueke Jiang, Li Lei, Meixi Peng, Jun Ren, Qiaoling Xiao, Yao Tao, Yonghong Tao, Junpeng Huang, Lu Wang, Yuting Tang, Zailin Yang, Zesong Yang, Ling Zhang, 2021
- NPM1 mutant mediated PML delocalization and stabilization enhances autophagy and cell survival in leukemic cells., Zou Q, Tan S, Yang Z, Zhan Q, Jin H, Xian J, Zhang S, Yang L, Wang L, Zhang L, 2017
- INPP4B promotes cell survival via SGK3 activation in NPM1-mutated leukemia., Jin H, Yang L, Wang L, Yang Z, Zhan Q, Tao Y, Zou Q, Tang Y, Xian J, Zhang S, Jing Y, Zhang L, 2018
Awards
- Qian De Teaching Excellence Award
