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Feng Li
Life Science
China Medical University
Liaoning
Language: English, Chinese
Pak Kinase
Signaling Pathways
Cancer
Small Molecule Inhibitors
Tumor Biology
Metastasis
Cell Signaling
Oncology
Biochemistry
Molecular Biology
Areas of Focus
- PAK kinase signaling pathways and cancer
- Screening of small molecule inhibitors
Work Experience
- Current - China Medical University - Director of the Department of Cell Biology
- Current - National Health Commission Key Laboratory of Cell Biology - Deputy Director
- Current - Ministry of Education Key Laboratory of Medical Cell Biology - Deputy Director
Academic Background & Achievements
- 2000.2-2002.12 Postdoctoral Research: MD Anderson Cancer Center
- Recipient of the State Council Special Allowance
Publications
- MORC2 regulates RBM39-mediated CDK5RAP2 alternative splicing to promote EMT and metastasis in colon cancer., He Y, Shao Y, Zhou Z, Li T, Gao Y, Liu X, Yuan G, Yang G, Zhang L, Li F, 2024
- PAK5 promotes RNA helicase DDX5 sumoylation and miRNA-10b processing in a kinase-dependent manner in breast cancer., Yang Li, Yao Xing, Xu Wang, Bingtao Hu, Xin Zhao, Hongyan Zhang, Fuyi Han, Nanxi Geng, Fei Wang, Yanshu Li, Jiabin Li, Feng Jin, Feng Li, 2021
- Mitochondrial PAK6 inhibits prostate cancer cell apoptosis via the PAK6-SIRT4-ANT2 complex., Li T, Li Y, Liu T, Hu B, Li J, Liu C, Liu T, Li F, 2020
- A mandatory role of nuclear PAK4-LIFR axis in breast-to-bone metastasis of ERα-positive breast cancer cells., Li Y, Zhang H, Zhao Y, Wang C, Cheng Z, Tang L, Gao Y, Liu F, Li J, Li Y, Li Y, Geng N, Rui X, Teng Y, Liu Y, Cao L, Kumar R, Jin F, Li F, 2019
- PAK5-mediated E47 phosphorylation promotes epithelial-mesenchymal transition and metastasis of colon cancer., Zhu G, Li X, Guo B, Ke Q, Dong M, Li F, 2016
- PAK4 kinase-mediated SCG10 phosphorylation involved in gastric cancer metastasis., Qiqiang Guo, Nan Su, Jian Zhang, Xiaodong Li, Zhifeng Miao, Guiling Wang, Maosheng Cheng, Huimian Xu, Liu Cao, Feng Li, 2014
- Oncogenic PAK4 regulates Smad2/3 axis involving gastric tumorigenesis., Chunyu Wang, Yanshu Li, Hongyan Zhang, Funan Liu, Zhenguo Cheng, Di Wang, Guiling Wang, Huimian Xu, Yue Zhao, Liu Cao, Feng Li, 2014
Awards
- 2014: Second Prize of Liaoning Province Science and Technology Progress Award
- 2015: First Prize of the Chinese Anti-Cancer Association Science and Technology Award
