Areas of Focus
- Epigenetic regulation mechanisms in brain homeostasis and disease progression
Work Experience
- Current - China Medical University - Associate Professor and Deputy Director of the Developmental Cell Biology Department
Academic Background & Achievements
- PhD in Biochemistry and Molecular Biology: Tsinghua University-Peking Union Medical College
- Supported by the China Scholarship Council for study in the USA
- Awarded by the Liaoning Provincial Government as an outstanding PhD graduate from a top 200 global university
Publications
- An oxygen-adaptive interaction between SNHG12 and occludin maintains blood-brain barrier integrity, Yuan Li; Jia-Yi Wei; Hui Liu; Kang-Ji Wang; Sheng-Nan Jin; Zheng-Kang Su; Hui-Jie Wang; Jun-Xiu Shi; Bo Li; De-Shu Shang; Wen-Gang Fang; Xiao-Xue Qin; Wei-Dong Zhao; Yu-Hua Chen, 2022
- Endothelial lincRNA-p21 alleviates cerebral ischemia/reperfusion injury by maintaining blood-brain barrier integrity, Yun-Hua Zhao, Yu Liang, Kang-Ji Wang, Sheng-Nan Jin, Xiao-Meng Yu, Qian Zhang, Jia-Yi Wei, Hui Liu, Wen-Gang Fang, Wei-Dong Zhao, Yuan Li, Yu-Hua Chen, 2024
- Endothelial depletion of Atg7 triggers astrocyte-microvascular disassociation at blood-brain barrier, Hui Liu; Jia-yi Wei; Yuan Li; Meng Ban; Qi Sun; Hui-Jie Wang; Dan Zhao; Pai-Ge Tong; Li Wang; Kang-Ji Wang; Jin-Li Yue; Hong-Yan Zhang; Wen-Gang Fang; Dong-Xin Liu; De-Shu Shang; Bo Li; Ya-Ping Jin; Liu Cao; Wei-Dong Zhao; Yu-Hua Chen, 2023
- Caspr1 Facilitates sAPPα Production by Regulating α-Secretase ADAM9 in Brain Endothelial Cells, Shi-Yu Tang; Dong-Xin Liu; Yuan Li; Kang-Ji Wang; Xia-Fei Wang; Zheng-Kang Su; Wen-Gang Fang; Xiao-Xue Qin; Jia-Yi Wei; Wei-Dong Zhao; Yu-Hua Chen, 2020
- Long non-coding RNA growth arrest specific transcript 5 acts as a tumour suppressor in colorectal cancer by inhibiting interleukin-10 and vascular endothelial growth factor expression, Li, Yuan; Li, Yan; Huang, Shengkai; He, Kun; Zhao, Mei; Lin, Hong; Li, Dongdong; Qian, Jiaming; Zhou, Caihong; Chen, Yuhua; Huang, Changzhi, 2017
- Decreased expression of LncRNA SLC25A25-AS1 promotes proliferation, chemoresistance, and EMT in colorectal cancer cells, Li, Yuan; Huang, Shengkai; Li, Yan; Zhang, Weilong; He, Kun; Zhao, Mei; Lin, Hong; Li, Dongdong; Zhang, Honggang; Zheng, Zhaoxu; Huang, Changzhi, 2016
- Circulating miRNAs Increasing the Risk of Cancer, Li Yuan; Li Yan; Huang Changzhi, 2017
Awards
- Liaoning Provincial Government Award: Outstanding PhD Graduate