Professor | Qi Xu | Asia Growth Partners

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Name	Qi Xu
Contact Information	xuqi@pumc.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Qi Xu

Contact Information

xuqi@pumc.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking Union Medical College
Faculty	Basic Medical Sciences
Academic Background & Achievements	1996 - Bachelor of Medicine: Beijing Medical University 2004 - PhD in Biochemistry and Molecular Biology: Peking Union Medical College 2016 - National Science Fund for Distinguished Young Scholars
Work Experience	1996-present - Peking Union Medical College - Researcher, Distinguished Professor 2009-present - Peking Union Medical College - Researcher, Doctoral Supervisor
Awards	2005 - Beijing Science and Technology New Star Program 2006 - Young Scientist Award by the International Schizophrenia Research Society 2008 - Eleventh Higher Education Young Teacher Award by the Fok Ying Tung Education Foundation and Ministry of Education 2010 - Sixth Batch of Beijing Outstanding Young Intellectuals 2015 - National 'Ten Thousand Talents Program' 2016 - China Youth Science and Technology Award

University/Lab Affiliation and Title

Peking Union Medical College

Faculty

Basic Medical Sciences

Academic Background & Achievements

1996 - Bachelor of Medicine: Beijing Medical University
2004 - PhD in Biochemistry and Molecular Biology: Peking Union Medical College
2016 - National Science Fund for Distinguished Young Scholars

Work Experience

1996-present - Peking Union Medical College - Researcher, Distinguished Professor
2009-present - Peking Union Medical College - Researcher, Doctoral Supervisor

Awards

2005 - Beijing Science and Technology New Star Program
2006 - Young Scientist Award by the International Schizophrenia Research Society
2008 - Eleventh Higher Education Young Teacher Award by the Fok Ying Tung Education Foundation and Ministry of Education
2010 - Sixth Batch of Beijing Outstanding Young Intellectuals
2015 - National 'Ten Thousand Talents Program'
2016 - China Youth Science and Technology Award

Areas of Focus	Identification of susceptibility genes and biomarkers for major psychiatric and neurological disorders Molecular pathological mechanisms of disease onset Exploration of therapeutic targets for diseases
Publications	Sparse whole-genome sequencing identifies two loci for major depressive disorder., Na Cai, Tim B. Bigdeli, Warren Kretzschmar, Yihan Li, Qi Xu, Jun Wang, Kenneth S. Kendler, Jonathan Flint, 2015 Detection of circulating miRNA levels in schizophrenia., Wei H, Yuan Y, Liu S, Wang C, Yang F, Lu Z, Wang C, Deng H, Zhao J, Shen Y, Zhang C, Yu X, Xu Q, 2015 Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy., Sha L, Wang X, Li J, Shi X, Wu L, Shen Y, Xu Q, 2017 Deletion of mTOR in Reactive Astrocytes Suppresses Chronic Seizures in a Mouse Model of Temporal Lobe Epilepsy., Wang X, Sha L, Sun N, Shen Y, Xu Q, 2017 Notch signaling activation promotes seizure activity in temporal lobe epilepsy., Sha L, Wu X, Yao Y, Wen B, Feng J, Sha Z, Wang X, Xing X, Dou W, Jin L, Li W, Wang N, Shen Y, Wang J, Wu L, Xu Q, 2014 Common variants on 8p12 and 1q24.2 confer risk of schizophrenia., Shi Y, Li Z, Xu Q, Wang T, Li T, Shen J, Zhang F, Chen J, Zhou G, Ji W, Li B, Xu Y, Liu D, Wang P, Yang P, Liu B, Sun W, Wan C, Qin S, He G, Steinberg S, Cichon S, Werge T, Sigurdsson E, Tosato S, Palotie A, Nöthen MM, Rietschel M, Ophoff RA, Collier DA, Rujescu D, Clair DS, Stefansson H, Stefansson K, Ji J, Wang Q, Li W, Zheng L, Zhang H, Feng G, He L, 2011 An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity., Weirui Guo, Yanbo Chen, Xiaohong Zhou, Amar Kar, Payal Ray, Xiaoping Chen, Elizabeth J Rao, Mengxue Yang, Haihong Ye, Li Zhu, Jianghong Liu, Meng Xu, Yanlian Yang, Chen Wang, David Zhang, Eileen H Bigio, Marsel Mesulam, Yan Shen, Qi Xu, Kazuo Fushimi, Jane Y Wu, 2011 A cis-Phase Interaction Study of Genetic Variants Within the MAOA Gene in Major Depressive Disorder., Zhang J, Chen Y, Zhang K, Yang H, Sun Y, Fang Y, Shen Y, Xu Q, 2010 Evidence of epistasis between catechol-O-methyltransferase gene and aldehyde dehydrogenase 3B1 gene in paranoid schizophrenia., Yan Wang, Ying Hu, Yue Fang, Kerang Zhang, Hong Yang, Jitang Ma, Qi Xu, Yan Shen, 2009 Association study of an SNP combination pattern in the dopaminergic pathway in paranoid schizophrenia: a novel strategy for complex disorders., Xu Q, Jia YB, Zhang BY, Zou K, Tao YB, Wang YP, Qiang BQ, Wu GY, Shen Y, Ji HK, Huang Y, Sun XQ, Ji L, Li YD, Yuan YB, Shu L, Yu X, Shen Y, Yu YQ, Ju GZ, 2004

Areas of Focus

Identification of susceptibility genes and biomarkers for major psychiatric and neurological disorders
Molecular pathological mechanisms of disease onset
Exploration of therapeutic targets for diseases

Publications

Sparse whole-genome sequencing identifies two loci for major depressive disorder., Na Cai, Tim B. Bigdeli, Warren Kretzschmar, Yihan Li, Qi Xu, Jun Wang, Kenneth S. Kendler, Jonathan Flint, 2015
Detection of circulating miRNA levels in schizophrenia., Wei H, Yuan Y, Liu S, Wang C, Yang F, Lu Z, Wang C, Deng H, Zhao J, Shen Y, Zhang C, Yu X, Xu Q, 2015
Pharmacologic inhibition of Hsp90 to prevent GLT-1 degradation as an effective therapy for epilepsy., Sha L, Wang X, Li J, Shi X, Wu L, Shen Y, Xu Q, 2017
Deletion of mTOR in Reactive Astrocytes Suppresses Chronic Seizures in a Mouse Model of Temporal Lobe Epilepsy., Wang X, Sha L, Sun N, Shen Y, Xu Q, 2017
Notch signaling activation promotes seizure activity in temporal lobe epilepsy., Sha L, Wu X, Yao Y, Wen B, Feng J, Sha Z, Wang X, Xing X, Dou W, Jin L, Li W, Wang N, Shen Y, Wang J, Wu L, Xu Q, 2014
Common variants on 8p12 and 1q24.2 confer risk of schizophrenia., Shi Y, Li Z, Xu Q, Wang T, Li T, Shen J, Zhang F, Chen J, Zhou G, Ji W, Li B, Xu Y, Liu D, Wang P, Yang P, Liu B, Sun W, Wan C, Qin S, He G, Steinberg S, Cichon S, Werge T, Sigurdsson E, Tosato S, Palotie A, Nöthen MM, Rietschel M, Ophoff RA, Collier DA, Rujescu D, Clair DS, Stefansson H, Stefansson K, Ji J, Wang Q, Li W, Zheng L, Zhang H, Feng G, He L, 2011
An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity., Weirui Guo, Yanbo Chen, Xiaohong Zhou, Amar Kar, Payal Ray, Xiaoping Chen, Elizabeth J Rao, Mengxue Yang, Haihong Ye, Li Zhu, Jianghong Liu, Meng Xu, Yanlian Yang, Chen Wang, David Zhang, Eileen H Bigio, Marsel Mesulam, Yan Shen, Qi Xu, Kazuo Fushimi, Jane Y Wu, 2011
A cis-Phase Interaction Study of Genetic Variants Within the MAOA Gene in Major Depressive Disorder., Zhang J, Chen Y, Zhang K, Yang H, Sun Y, Fang Y, Shen Y, Xu Q, 2010
Evidence of epistasis between catechol-O-methyltransferase gene and aldehyde dehydrogenase 3B1 gene in paranoid schizophrenia., Yan Wang, Ying Hu, Yue Fang, Kerang Zhang, Hong Yang, Jitang Ma, Qi Xu, Yan Shen, 2009
Association study of an SNP combination pattern in the dopaminergic pathway in paranoid schizophrenia: a novel strategy for complex disorders., Xu Q, Jia YB, Zhang BY, Zou K, Tao YB, Wang YP, Qiang BQ, Wu GY, Shen Y, Ji HK, Huang Y, Sun XQ, Ji L, Li YD, Yuan YB, Shu L, Yu X, Shen Y, Yu YQ, Ju GZ, 2004

Susceptibility Genes Biomarkers Psychiatric Disorders Neurological Disorders Molecular Pathology Disease Onset Therapeutic Targets Gene-Environment Interaction Neurobiology Genetic Research

Ai-Ling Li - Fudan University

Weimin Qu - Fudan University

Qiuzhen Liu - Southern Medical University

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