Areas of Focus
- Pathological mechanisms, molecular diagnosis, and treatment of cardiopulmonary vascular diseases
Work Experience
- 2009-2012 - Postdoctoral Researcher: Harvard Medical School
- 2012-2013 - Lecturer: Harvard Medical School
- Current - Deputy Director and Deputy Secretary: Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
Academic Background & Achievements
- 2003 - Bachelor's Degree: Peking University Health Science Center
- 2009 - PhD in Pathology: University of Rochester
- 2014 - Selected for National Excellent Young Talent Project
- 2016 - Received National Natural Science Foundation 'Excellent Young Scientist Fund'
- 2020 - Appointed as Distinguished Professor in Major Talent Project by Ministry of Education
- 2022 - Received Mao Yisheng Youth Science and Technology Award
Publications
- Gefitinib and fostamatinib target EGFR and SYK to attenuate silicosis: a multi-omics study with drug exploration, Wang M, Zhang Z, Liu J, Song M, Zhang T, Chen Y, Hu H, Yang P, Li B, Song X, Pang J, Xing Y, Cao Z, Guo W, Yang H, Wang J, Yang J, Wang C, 2022
- Single-cell transcriptomics of mouse lung reveal inflammatory memory neutrophils in allergic asthma, Li Z, Feng Y, Liu H, Yang H, Li J, Zhou Y, Pang J, Yang P, Zhao H, Wang J, 2022
- The role of immunoglobulin E and mast cells in hypertension, Ge W, Guo X, Song X, Pang J, Zou X, Liu Y, Niu Y, Li Z, Gao R, Zhao H, Wang J, 2022
- Phosphodiesterase 4D promotes angiotensin II-induced hypertension in mice via smooth muscle cell contraction, Fan T, Hou Y, Ge W, Fan TH, Guo W, Song X, Gao R, Wang J, 2022
- Role of IgE-FcεR1 in Pathological Cardiac Remodeling and Dysfunction, Zhao H, Yang H, Geng C, Chen Y, Pang J, Shu T, Zhao M, Tang Y, Li B, Li Z, Hou C, Song X, Wu A, Guo X, Chen S, Liu B, Yan C, Wang J, 2021
- SARS-CoV-2 leads to myocardial injury in rhesus macaque, Feng Y, Song X, Huang Y, Deng W, Li M, Guo X, Qin C, Tong W, Liu J, Wang J, 2021
- Blocking FcγRIIB in smooth muscle cells reduces hypertension, Song X, Zou X, Ge W, Hou C, Cao Z, Zhao H, Zhang T, Jin L, Fu Y, Kong W, Yan C, Cai J, Wang J, 2021
- Elevated IgE promotes cardiac fibrosis by suppressing miR-486-5p, Zhao H, Yang H, Geng C, Chen Y, Tang Y, Li Z, Pang J, Shu T, Nie Y, Liu Y, Jia K, Wang J, 2021
- Inhibition of gasdermin D-dependent pyroptosis attenuates the progression of silica-induced pulmonary inflammation and fibrosis, Song M, Wang J, Sun Y, Pang J, Li X, Liu Y, Zhou Y, Yang P, Fan T, Liu Y, Li Z, Qi X, Li B, Zhang X, Wang J, Wang C, 2021
- Eosinophils improve cardiac function after myocardial infarction, Liu J, Yang C, Liu T, Deng Z, Fang W, Zhang X, Li J, Huang Q, Liu C, Wang Y, Yang D, Sukhova GK, Lindholt JS, Diederichsen A, Rasmussen LM, Li D, Newton G, Luscinskas FW, Liu L, Libby P, Wang J, Guo J, Shi GP, 2020
- Multi-omics study of silicosis reveals the potential therapeutic targets PGD2 and TXA2, Pang JL, Qi XM, Luo Y, Li XN, Shu T, Li BC, Song MY, Liu Y, Wei D, Wang J, Chen Jingyu, Chen Wang, 2021
Awards
- 2014: Selected for National Excellent Young Talent Project
- 2016: Received National Natural Science Foundation 'Excellent Young Scientist Fund'
- 2020: Appointed as Distinguished Professor in Major Talent Project by Ministry of Education
- 2022: Received Mao Yisheng Youth Science and Technology Award
